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Entry version 128 (29 Sep 2021)
Sequence version 2 (31 Oct 2006)
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Protein

FERM and PDZ domain-containing protein 3

Gene

FRMPD3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q5JV73

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-6798695, Neutrophil degranulation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
FERM and PDZ domain-containing protein 3
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:FRMPD3
Synonyms:KIAA1817
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:29382, FRMPD3

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
301005, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q5JV73

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000147234

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA143485474

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q5JV73, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
FRMPD3

Domain mapping of disease mutations (DMDM)

More...
DMDMi
118582027

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002546501 – 1810FERM and PDZ domain-containing protein 3Add BLAST1810

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q5JV73

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q5JV73

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q5JV73

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q5JV73

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q5JV73

PeptideAtlas

More...
PeptideAtlasi
Q5JV73

PRoteomics IDEntifications database

More...
PRIDEi
Q5JV73

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
63310

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q5JV73

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q5JV73

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000147234, Expressed in left lobe of thyroid gland and 98 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q5JV73, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q5JV73, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000147234, Tissue enhanced (brain, ovary, thyroid gland)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
124081, 1 interactor

Protein interaction database and analysis system

More...
IntActi
Q5JV73, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000276185

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q5JV73, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q5JV73

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini54 – 131PDZPROSITE-ProRule annotationAdd BLAST78
Domaini180 – 494FERMPROSITE-ProRule annotationAdd BLAST315

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni524 – 553DisorderedSequence analysisAdd BLAST30
Regioni588 – 607DisorderedSequence analysisAdd BLAST20
Regioni655 – 730DisorderedSequence analysisAdd BLAST76
Regioni865 – 904DisorderedSequence analysisAdd BLAST40
Regioni1047 – 1249DisorderedSequence analysisAdd BLAST203
Regioni1342 – 1379DisorderedSequence analysisAdd BLAST38
Regioni1765 – 1798DisorderedSequence analysisAdd BLAST34

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi535 – 549Polar residuesSequence analysisAdd BLAST15
Compositional biasi708 – 725Basic and acidic residuesSequence analysisAdd BLAST18
Compositional biasi1047 – 1108Polar residuesSequence analysisAdd BLAST62
Compositional biasi1127 – 1142Polar residuesSequence analysisAdd BLAST16
Compositional biasi1165 – 1239Polar residuesSequence analysisAdd BLAST75
Compositional biasi1765 – 1780Polar residuesSequence analysisAdd BLAST16

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3552, Eukaryota

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q5JV73

Identification of Orthologs from Complete Genome Data

More...
OMAi
CTSQTDC

Database of Orthologous Groups

More...
OrthoDBi
24326at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q5JV73

TreeFam database of animal gene trees

More...
TreeFami
TF316497

Family and domain databases

Conserved Domains Database

More...
CDDi
cd14473, FERM_B-lobe, 1 hit
cd13183, FERM_C_FRMPD1_FRMPD3_FRMPD4, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.80.10, 1 hit
2.30.29.30, 1 hit
2.30.42.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR019749, Band_41_domain
IPR014352, FERM/acyl-CoA-bd_prot_sf
IPR035963, FERM_2
IPR019748, FERM_central
IPR000299, FERM_domain
IPR041779, FRMPD1/3/4_FERM_C
IPR001478, PDZ
IPR036034, PDZ_sf
IPR011993, PH-like_dom_sf
IPR029071, Ubiquitin-like_domsf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00373, FERM_M, 1 hit
PF00595, PDZ, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00295, B41, 1 hit
SM00228, PDZ, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47031, SSF47031, 1 hit
SSF50156, SSF50156, 1 hit
SSF54236, SSF54236, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50057, FERM_3, 1 hit
PS50106, PDZ, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

Q5JV73-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
METLDSQRVQ DRLLAAPGCS SPSGQQELFS SHVMQEESAN DMECEQLPAE
60 70 80 90 100
ILRQVTVHRD PIYGFGFVAG SERPVVVRSV RPGGPSENKL LAGDQIVAIN
110 120 130 140 150
EEDVSEAPRE RLIELIRSAK EFIVLTVLHT HQSPKSAFIS AAKKAKLRSN
160 170 180 190 200
PVKVRFSEQV AVGETDAKMM KKEALLLIPN VLKVFLENGQ IKSFTFDGRT
210 220 230 240 250
TVKDVMLTLQ DRLSLRFIEH FALVLEYAGP EQNHKFLLLQ DKQPLAYVVQ
260 270 280 290 300
RTHYHGMKCL FRISFFPKDP VELLRRDPAA FEYLYIQSRN DVIRERFGMD
310 320 330 340 350
PKPEMLLGLA ALHIYITVSA TRPSQKISLK NVEKEWGLEP FLPPSLLQVI
360 370 380 390 400
KEKNLRKSLS QQLKAHQTHP SCGTKGSAIQ AKLQYLRILN ELPTFTGVLF
410 420 430 440 450
NTVGLDEKQS ATTLLVGPRH GISHVIDLKT NLTTVLSEFS KISKIQLFRE
460 470 480 490 500
NQGVARVETS IMDAKPLVLL MEWPEATNFA CLIAGYCRLL LDSRKMVFSR
510 520 530 540 550
PASQPLPPPM IKADYMHSAH RPVTGGHLGK KESSYVGSVG TSPRKSSRCT
560 570 580 590 600
PPPADSELVS FCYLHMREQR KEQESRTDVN ENLIFFEETR PRTKSDPTSK
610 620 630 640 650
SSGQGYEVVP DDFDAASLDH EPCASRARSY TLDNSLGAEA LNFYCDSCKA
660 670 680 690 700
KLQEQLGPRK GGKPGSSRDN IVDLMSLPPP GSEEEEEEED ETTSLLPAIA
710 720 730 740 750
APPPGFRDNS SDEDDPKRRA VQSQEQGRHL RGLLYDEIPV TLIDSVQTRT
760 770 780 790 800
VRDHAQELDD ALVSTLQALE ALAASEDGPH PPPPQTAGLI VLATITPESS
810 820 830 840 850
LDSGHETNSS ELTDMSEMMS AMKQHQNTTY FLAQHLNKDS LLARKDLPFR
860 870 880 890 900
IQSCAAQAVL TAPYSLGRPD PNPSLQPIAT GQSPGPPGAR RKLPQSEGQV
910 920 930 940 950
QGERTYSLAV HPALSPQLSE QKNLSLLSPV PEDKGPGHTR AGLEMSLRAA
960 970 980 990 1000
TSSLSEEQVS ELRDNLPKEV RLSPKLILDP KSSVTPAIIS AALQQVVHNK
1010 1020 1030 1040 1050
SLVTAGGALG NPPSRGERRL EASMGRPEVS MMSSSASKNL KFKISPSAPE
1060 1070 1080 1090 1100
TSWNSQHQLG AEVSSSPRAP TGSRADSLHL SQQEDSLPVQ NFPPKSYLLR
1110 1120 1130 1140 1150
TSRESVGKQA TGEVAGKGGP VGGKPTLQKQ GTISSQGEKA QLESTPKRSK
1160 1170 1180 1190 1200
LEETSLVPRA TYPMALQSPS CQSRSHSPSC QPHGHSPSSQ SRGQSPSCQP
1210 1220 1230 1240 1250
RGQSPLRSQA ASRQVSTMPS RKLETTLNGA HSTSEGPAKP KSSRGPFRLR
1260 1270 1280 1290 1300
NLFSATFPTR QKKETDERQA QLQKVKQYEL EFLEELLKPP SQGELPGTEY
1310 1320 1330 1340 1350
LQPPAPGRCS CQLRSSPVQQ GPGMSREQRR SCDCKRICRG GRPQATQTPV
1360 1370 1380 1390 1400
PSLRGRERDR VLPSQRQPEA GPGVSLSSPI NVQRIRSTSL ESRECRSDPE
1410 1420 1430 1440 1450
SGVSCLTTCA SGGECLGAPN YRKLMRRYSI SELDQGDRAS LTSDVYPHPP
1460 1470 1480 1490 1500
LGMLPREAKE VEASLPIALG PKSRSLESPT LGDPSYVQVA PETKGPRQMA
1510 1520 1530 1540 1550
VFSLPEEVYR KPAELDEDSE SSKCCSIRYC FYYRKCDMAD DASDGKDELS
1560 1570 1580 1590 1600
YSIPMKILPG MKLDEQVVPV VSRTLQVLDA ATCSSSSPEA SRTQEIDLRV
1610 1620 1630 1640 1650
STFEGSLAKI NALRAHAYGL PDGFLAARLD TNELLTVLRQ CVASPEARAP
1660 1670 1680 1690 1700
KPYVSQISEY KLELALKFKE LRASCRRVAN VDKSPTHMLA AITGSFQVLS
1710 1720 1730 1740 1750
SLIETFVRLV FIVRSEAQRQ ELLAKVEEVV RNYTFLLRAA EESTARNLNQ
1760 1770 1780 1790 1800
QQQQQQQQQQ QQQQQQQQQQ QQQQQQVAAA AGAATEHPPG SPTSATVMST
1810
FTHSLKTLIK
Length:1,810
Mass (Da):199,209
Last modified:October 31, 2006 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9FC42A38E6B682BB
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0A0MSP7A0A0A0MSP7_HUMAN
FERM and PDZ domain-containing prot...
FRMPD3
1,758Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A804HJA6A0A804HJA6_HUMAN
FERM and PDZ domain-containing prot...
FRMPD3
1,642Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A804HKI5A0A804HKI5_HUMAN
FERM and PDZ domain-containing prot...
FRMPD3
1,777Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A804HKR2A0A804HKR2_HUMAN
FERM and PDZ domain-containing prot...
FRMPD3
314Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti814 – 822DMSEMMSAM → ALKSWFHDL in BAB47446 (PubMed:11347906).Curated9

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL035088 Genomic DNA No translation available.
AL137787 Genomic DNA No translation available.
AB058720 mRNA Translation: BAB47446.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS76006.1

NCBI Reference Sequences

More...
RefSeqi
NP_115804.1, NM_032428.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000276185; ENSP00000276185; ENSG00000147234

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
84443

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:84443

UCSC genome browser

More...
UCSCi
uc033eqj.1, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL035088 Genomic DNA No translation available.
AL137787 Genomic DNA No translation available.
AB058720 mRNA Translation: BAB47446.1
CCDSiCCDS76006.1
RefSeqiNP_115804.1, NM_032428.1

3D structure databases

SMRiQ5JV73
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi124081, 1 interactor
IntActiQ5JV73, 1 interactor
STRINGi9606.ENSP00000276185

PTM databases

iPTMnetiQ5JV73
PhosphoSitePlusiQ5JV73

Genetic variation databases

BioMutaiFRMPD3
DMDMi118582027

Proteomic databases

EPDiQ5JV73
jPOSTiQ5JV73
MassIVEiQ5JV73
MaxQBiQ5JV73
PaxDbiQ5JV73
PeptideAtlasiQ5JV73
PRIDEiQ5JV73
ProteomicsDBi63310

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
572, 47 antibodies

The DNASU plasmid repository

More...
DNASUi
84443

Genome annotation databases

EnsembliENST00000276185; ENSP00000276185; ENSG00000147234
GeneIDi84443
KEGGihsa:84443
UCSCiuc033eqj.1, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
84443

GeneCards: human genes, protein and diseases

More...
GeneCardsi
FRMPD3
HGNCiHGNC:29382, FRMPD3
HPAiENSG00000147234, Tissue enhanced (brain, ovary, thyroid gland)
MIMi301005, gene
neXtProtiNX_Q5JV73
PharmGKBiPA143485474
VEuPathDBiHostDB:ENSG00000147234

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3552, Eukaryota
InParanoidiQ5JV73
OMAiCTSQTDC
OrthoDBi24326at2759
PhylomeDBiQ5JV73
TreeFamiTF316497

Enzyme and pathway databases

PathwayCommonsiQ5JV73
ReactomeiR-HSA-6798695, Neutrophil degranulation

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
84443, 1 hit in 163 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
FRMPD3, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
84443
PharosiQ5JV73, Tdark

Protein Ontology

More...
PROi
PR:Q5JV73
RNActiQ5JV73, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000147234, Expressed in left lobe of thyroid gland and 98 other tissues
ExpressionAtlasiQ5JV73, baseline and differential
GenevisibleiQ5JV73, HS

Family and domain databases

CDDicd14473, FERM_B-lobe, 1 hit
cd13183, FERM_C_FRMPD1_FRMPD3_FRMPD4, 1 hit
Gene3Di1.20.80.10, 1 hit
2.30.29.30, 1 hit
2.30.42.10, 1 hit
InterProiView protein in InterPro
IPR019749, Band_41_domain
IPR014352, FERM/acyl-CoA-bd_prot_sf
IPR035963, FERM_2
IPR019748, FERM_central
IPR000299, FERM_domain
IPR041779, FRMPD1/3/4_FERM_C
IPR001478, PDZ
IPR036034, PDZ_sf
IPR011993, PH-like_dom_sf
IPR029071, Ubiquitin-like_domsf
PfamiView protein in Pfam
PF00373, FERM_M, 1 hit
PF00595, PDZ, 1 hit
SMARTiView protein in SMART
SM00295, B41, 1 hit
SM00228, PDZ, 1 hit
SUPFAMiSSF47031, SSF47031, 1 hit
SSF50156, SSF50156, 1 hit
SSF54236, SSF54236, 1 hit
PROSITEiView protein in PROSITE
PS50057, FERM_3, 1 hit
PS50106, PDZ, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiFRPD3_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5JV73
Secondary accession number(s): Q96JK8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: October 31, 2006
Last modified: September 29, 2021
This is version 128 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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