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Protein

Testis-expressed protein 30

Gene

TEX30

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Protein family/group databases

ESTHERihuman-TEX30 NLS3-Tex30

Names & Taxonomyi

Protein namesi
Recommended name:
Testis-expressed protein 30
Gene namesi
Name:TEX30
Synonyms:C13orf27
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 13

Organism-specific databases

EuPathDBiHostDB:ENSG00000151287.16
HGNCiHGNC:25188 TEX30
neXtProtiNX_Q5JUR7

Pathology & Biotechi

Organism-specific databases

DisGeNETi93081
OpenTargetsiENSG00000151287
PharmGKBiPA147358470

Chemistry databases

ChEMBLiCHEMBL2189125

Polymorphism and mutation databases

DMDMi74742331

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002743121 – 227Testis-expressed protein 30Add BLAST227

Proteomic databases

EPDiQ5JUR7
MaxQBiQ5JUR7
PaxDbiQ5JUR7
PeptideAtlasiQ5JUR7
PRIDEiQ5JUR7
ProteomicsDBi63288

PTM databases

iPTMnetiQ5JUR7
PhosphoSitePlusiQ5JUR7

Expressioni

Gene expression databases

BgeeiENSG00000151287
CleanExiHS_C13orf27
ExpressionAtlasiQ5JUR7 baseline and differential
GenevisibleiQ5JUR7 HS

Organism-specific databases

HPAiHPA053545

Interactioni

Protein-protein interaction databases

BioGridi124998, 3 interactors
STRINGi9606.ENSP00000365200

Structurei

3D structure databases

ProteinModelPortaliQ5JUR7
SMRiQ5JUR7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410ITSK Eukaryota
COG3571 LUCA
GeneTreeiENSGT00390000016489
HOGENOMiHOG000006654
HOVERGENiHBG081256
InParanoidiQ5JUR7
OMAiYPLHRPK
OrthoDBiEOG091G0IVV
PhylomeDBiQ5JUR7
TreeFamiTF332335

Family and domain databases

Gene3Di3.40.50.1820, 1 hit
InterProiView protein in InterPro
IPR029058 AB_hydrolase
IPR002925 Dienelactn_hydro
IPR026555 NSL3/Tex30
PANTHERiPTHR13136 PTHR13136, 1 hit
PfamiView protein in Pfam
PF01738 DLH, 1 hit
SUPFAMiSSF53474 SSF53474, 1 hit

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q5JUR7-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MSHTEVKLKI PFGNKLLDAV CLVPNKSLTY GIILTHGASG DMNLPHLMSL
60 70 80 90 100
ASHLASHGFF CLRFTCKGLN IVHRIKAYKS VLNYLKTSGE YKLAGVFLGG
110 120 130 140 150
RSMGSRAAAS VMCHIEPDDG DDFVRGLICI SYPLHHPKQQ HKLRDEDLFR
160 170 180 190 200
LKEPVLFVSG SADEMCEKNL LEKVAQKMQA PHKIHWIEKA NHSMAVKGRS
210 220
TNDVFKEINT QILFWIQEIT EMDKKCH
Length:227
Mass (Da):25,585
Last modified:February 15, 2005 - v1
Checksum:iB37C06A38A91E774
GO
Isoform 2 (identifier: Q5JUR7-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     100-113: GRSMGSRAAASVMC → ELVGESGTENASSP
     114-227: Missing.

Note: No experimental confirmation available. Gene prediction based on EST data.
Show »
Length:113
Mass (Da):12,220
Checksum:i6C724738FA56E3E2
GO

Sequence cautioni

The sequence AAH15148 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_055706100 – 113GRSMG…ASVMC → ELVGESGTENASSP in isoform 2. CuratedAdd BLAST14
Alternative sequenceiVSP_055707114 – 227Missing in isoform 2. CuratedAdd BLAST114

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL157769 Genomic DNA No translation available.
BC015148 mRNA Translation: AAH15148.2 Different initiation.
CCDSiCCDS66578.1 [Q5JUR7-2]
CCDS9503.2 [Q5JUR7-1]
RefSeqiNP_001273704.1, NM_001286775.1 [Q5JUR7-2]
NP_001273705.1, NM_001286776.1
NP_620134.3, NM_138779.4 [Q5JUR7-1]
XP_005254154.1, XM_005254097.2 [Q5JUR7-1]
XP_011519437.1, XM_011521135.2 [Q5JUR7-1]
XP_016876341.1, XM_017020852.1 [Q5JUR7-1]
UniGeneiHs.398111

Genome annotation databases

EnsembliENST00000376027; ENSP00000365195; ENSG00000151287 [Q5JUR7-2]
ENST00000376029; ENSP00000365197; ENSG00000151287 [Q5JUR7-2]
ENST00000376032; ENSP00000365200; ENSG00000151287 [Q5JUR7-1]
GeneIDi93081
KEGGihsa:93081
UCSCiuc001vpn.5 human [Q5JUR7-1]

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Entry informationi

Entry nameiTEX30_HUMAN
AccessioniPrimary (citable) accession number: Q5JUR7
Secondary accession number(s): Q5JUR8, Q96KZ8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: February 15, 2005
Last modified: June 20, 2018
This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 13
    Human chromosome 13: entries, gene names and cross-references to MIM

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