UniProtKB - Q5JSB6 (Q5JSB6_HUMAN)
Protein
Submitted name:
Transcription factor Dp-1
Gene
TFDP1
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- DNA binding Source: UniProtKB-KW
- DNA-binding transcription factor activity Source: InterPro
GO - Biological processi
- regulation of cell cycle Source: InterPro
Keywordsi
Molecular function | DNA-bindingUniRule annotation |
Biological process | Transcription, Transcription regulationUniRule annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Transcription factor Dp-1Imported |
Gene namesi | Name:TFDP1Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000198176.12 |
HGNCi | HGNC:11749, TFDP1 |
Subcellular locationi
Nucleus
- Nucleus UniRule annotation
Nucleus
- nucleoplasm Source: HPA
Other locations
- transcription regulator complex Source: InterPro
Keywords - Cellular componenti
NucleusUniRule annotationExpressioni
Gene expression databases
Bgeei | ENSG00000198176, Expressed in trabecular bone tissue and 247 other tissues |
ExpressionAtlasi | Q5JSB6, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 111 – 157 | E2F_TDPInterPro annotationAdd BLAST | 47 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 72 – 117 | DisorderedSequence analysisAdd BLAST | 46 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 72 – 102 | PolarSequence analysisAdd BLAST | 31 | |
Compositional biasi | 103 – 117 | PolyampholyteSequence analysisAdd BLAST | 15 |
Sequence similaritiesi
Phylogenomic databases
GeneTreei | ENSGT00940000154652 |
HOGENOMi | CLU_1673226_0_0_1 |
Family and domain databases
Gene3Di | 1.10.10.10, 1 hit |
InterProi | View protein in InterPro IPR028313, DP-1 IPR003316, E2F_WHTH_DNA-bd_dom IPR015648, Transcrpt_fac_DP IPR036388, WH-like_DNA-bd_sf |
PANTHERi | PTHR12548, PTHR12548, 1 hit PTHR12548:SF4, PTHR12548:SF4, 1 hit |
Pfami | View protein in Pfam PF02319, E2F_TDP, 1 hit |
SMARTi | View protein in SMART SM01372, E2F_TDP, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All
Q5JSB6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAKDAGLIEA NGELKVFIDQ NLSPGKGVVS LVAVHPSTVN PLGKQLLPKT
60 70 80 90 100
FGQSNVNIAQ QVVIGTPQRP AASNTLVVGS PHTPSTHFAS QNQPSDSSPW
110 120 130 140 150
SAGKRNRKGE KNGKGLRHFS MKVCEKVQRK GTTSYNEVAD ELVAEFSAAD
NHILPNES
Computationally mapped potential isoform sequencesi
There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ14186 | TFDP1_HUMAN | Transcription factor Dp-1 | TFDP1 DP1 | 410 | Annotation score: | ||
Q5JSB5 | Q5JSB5_HUMAN | Transcription factor Dp-1 | TFDP1 | 235 | Annotation score: | ||
F5H452 | F5H452_HUMAN | Transcription factor Dp-1 | TFDP1 | 119 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 158 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL442125 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000453989; ENSP00000401389; ENSG00000198176 |
UCSCi | uc058yoc.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL442125 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
IntActi | Q5JSB6, 1 interactor |
MINTi | Q5JSB6 |
Proteomic databases
PeptideAtlasi | Q5JSB6 |
PRIDEi | Q5JSB6 |
ProteomicsDBi | 63142 |
Protocols and materials databases
Antibodypediai | 11828, 352 antibodies |
Genome annotation databases
Ensembli | ENST00000453989; ENSP00000401389; ENSG00000198176 |
UCSCi | uc058yoc.1, human |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000198176.12 |
HGNCi | HGNC:11749, TFDP1 |
OpenTargetsi | ENSG00000198176 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000154652 |
HOGENOMi | CLU_1673226_0_0_1 |
Miscellaneous databases
ChiTaRSi | TFDP1, human |
Gene expression databases
Bgeei | ENSG00000198176, Expressed in trabecular bone tissue and 247 other tissues |
ExpressionAtlasi | Q5JSB6, baseline and differential |
Family and domain databases
Gene3Di | 1.10.10.10, 1 hit |
InterProi | View protein in InterPro IPR028313, DP-1 IPR003316, E2F_WHTH_DNA-bd_dom IPR015648, Transcrpt_fac_DP IPR036388, WH-like_DNA-bd_sf |
PANTHERi | PTHR12548, PTHR12548, 1 hit PTHR12548:SF4, PTHR12548:SF4, 1 hit |
Pfami | View protein in Pfam PF02319, E2F_TDP, 1 hit |
SMARTi | View protein in SMART SM01372, E2F_TDP, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q5JSB6_HUMAN | |
Accessioni | Q5JSB6Primary (citable) accession number: Q5JSB6 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | February 15, 2005 |
Last sequence update: | October 5, 2016 | |
Last modified: | August 12, 2020 | |
This is version 133 of the entry and version 8 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |