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Protein

Putative peptide YY-3

Gene

PYY3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Protein uncertaini

Functioni

Caution

Could be the product of a pseudogene.Curated

GO - Molecular functioni

  • G protein-coupled receptor binding Source: GO_Central
  • neuropeptide hormone activity Source: GO_Central

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Putative peptide YY-3
Short name:
Putative peptide YY3
Alternative name(s):
PYY-III
Gene namesi
Name:PYY3
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Unplaced

Organism-specific databases

HGNCiHGNC:31855 PYY3
neXtProtiNX_Q5JQD4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Organism-specific databases

DisGeNETi644059

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_000034124424 – 70Putative peptide YY-3Add BLAST47

Proteomic databases

PRIDEiQ5JQD4
ProteomicsDBi63042

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliQ5JQD4
SMRiQ5JQD4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the NPY family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

HOVERGENiHBG006485
InParanoidiQ5JQD4
PhylomeDBiQ5JQD4

Family and domain databases

CDDicd00126 PAH, 1 hit
InterProiView protein in InterPro
IPR001955 Pancreatic_hormone-like
PANTHERiPTHR10533 PTHR10533, 1 hit
PfamiView protein in Pfam
PF00159 Hormone_3, 1 hit
PRINTSiPR00278 PANCHORMONE
ProDomiView protein in ProDom or Entries sharing at least one domain
PD001267 Pancreatic_hormone-like, 1 hit
SMARTiView protein in SMART
SM00309 PAH, 1 hit
PROSITEiView protein in PROSITE
PS50276 PANCREATIC_HORMONE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q5JQD4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVSVCRPWPA VAIALLALLV CLGALVDTCP IKPEAPGEDE SLEELSHYYA
60 70
SLCHYLNVVT RQWWEGADMW
Length:70
Mass (Da):7,832
Last modified:February 15, 2005 - v1
Checksum:i638605CCB943DD08
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_04403328T → I. Corresponds to variant dbSNP:rs5953365Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO393402 Genomic DNA No translation available.

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO393402 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliQ5JQD4
SMRiQ5JQD4
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ5JQD4
ProteomicsDBi63042

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

DisGeNETi644059
GeneCardsiPYY3
HGNCiHGNC:31855 PYY3
neXtProtiNX_Q5JQD4
GenAtlasiSearch...

Phylogenomic databases

HOVERGENiHBG006485
InParanoidiQ5JQD4
PhylomeDBiQ5JQD4

Family and domain databases

CDDicd00126 PAH, 1 hit
InterProiView protein in InterPro
IPR001955 Pancreatic_hormone-like
PANTHERiPTHR10533 PTHR10533, 1 hit
PfamiView protein in Pfam
PF00159 Hormone_3, 1 hit
PRINTSiPR00278 PANCHORMONE
ProDomiView protein in ProDom or Entries sharing at least one domain
PD001267 Pancreatic_hormone-like, 1 hit
SMARTiView protein in SMART
SM00309 PAH, 1 hit
PROSITEiView protein in PROSITE
PS50276 PANCREATIC_HORMONE_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiPYY3_HUMAN
AccessioniPrimary (citable) accession number: Q5JQD4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: February 15, 2005
Last modified: November 7, 2018
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
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