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Entry version 130 (13 Feb 2019)
Sequence version 2 (20 Feb 2007)
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Protein

Zinc finger protein 311

Gene

ZNF311

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri247 – 269C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri275 – 297C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri303 – 325C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri331 – 353C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri359 – 381C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri387 – 409C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri415 – 437C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri443 – 465C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri471 – 493C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri499 – 521C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri527 – 549C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri555 – 577C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri583 – 605C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri611 – 634C2H2-type 14PROSITE-ProRule annotationAdd BLAST24

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-212436 Generic Transcription Pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 311
Alternative name(s):
Zinc finger protein zfp-31
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF311
Synonyms:ZFP31
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000197935.6

Human Gene Nomenclature Database

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HGNCi
HGNC:13847 ZNF311

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q5JNZ3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
282890

Open Targets

More...
OpenTargetsi
ENSG00000197935

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134865305

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZNF311

Domain mapping of disease mutations (DMDM)

More...
DMDMi
143758539

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002804041 – 666Zinc finger protein 311Add BLAST666

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q5JNZ3

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q5JNZ3

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q5JNZ3

PeptideAtlas

More...
PeptideAtlasi
Q5JNZ3

PRoteomics IDEntifications database

More...
PRIDEi
Q5JNZ3

ProteomicsDB human proteome resource

More...
ProteomicsDBi
62993

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q5JNZ3

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q5JNZ3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000197935 Expressed in 123 organ(s), highest expression level in amniotic fluid

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q5JNZ3 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q5JNZ3 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA050541

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
129424, 5 interactors

Protein interaction database and analysis system

More...
IntActi
Q5JNZ3, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000366384

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q5JNZ3

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q5JNZ3

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini64 – 135KRABPROSITE-ProRule annotationAdd BLAST72

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri247 – 269C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri275 – 297C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri303 – 325C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri331 – 353C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri359 – 381C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri387 – 409C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri415 – 437C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri443 – 465C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri471 – 493C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri499 – 521C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri527 – 549C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri555 – 577C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri583 – 605C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri611 – 634C2H2-type 14PROSITE-ProRule annotationAdd BLAST24

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1721 Eukaryota
COG5048 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000163512

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000234617

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG018163

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q5JNZ3

KEGG Orthology (KO)

More...
KOi
K09228

Identification of Orthologs from Complete Genome Data

More...
OMAi
EWQCLTH

Database of Orthologous Groups

More...
OrthoDBi
1318335at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q5JNZ3

TreeFam database of animal gene trees

More...
TreeFami
TF341635

Family and domain databases

Conserved Domains Database

More...
CDDi
cd07765 KRAB_A-box, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 8 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 14 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 8 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 14 hits
PS50157 ZINC_FINGER_C2H2_2, 14 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q5JNZ3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQEVVLLDES SGPPSQLLWT RQDTQLPQES ALLPAPYPAF TKDGSQGNLP
60 70 80 90 100
QADITLMSQA QESVTFEDVA VNFTNREWQC LTYAQRHLYK DVMLENYGNM
110 120 130 140 150
VSLGFPFPKP PLISHLEREV DPCVQDPQDR ESLSCSYPVS ADKMWPENEK
160 170 180 190 200
ASSQQEIFEN GEAYWMKFNS LLKVDSRDPK VREVCVQDVK LENQWETSIR
210 220 230 240 250
EKLREEKEGS EEVTCKKGKN QKVLSKNLNP NSKHSQCNKV LIAQKLHECA
260 270 280 290 300
RCGKNFSWHS DLILHEQIHS GEKPHVCNEC GKAFKTRNQL SMHRIIHTGE
310 320 330 340 350
KPFNCTQCGK AFNSRSALCR HKKTHSGEKP HECRDCGKAF KTRNRLCMHQ
360 370 380 390 400
LIHTGEKPYK CNCCGKAFQF KHSLTIHGRI HTGEKPYECE ECGKAFSGSS
410 420 430 440 450
DLTKHIRIHT GERPYECSKC GRAFSRSSDL SKHKRIHTRE KHYGCPQCGK
460 470 480 490 500
DFSIKAELTK HRRIHTEEKR YRCEECGKAF RHNCKRRAHE REHTGEKPYQ
510 520 530 540 550
CRDCGKTFQD KHCLTIHQRI HTGEKPYKCL ECGKAFSGKS NLTNHRRIHT
560 570 580 590 600
GEKPHKCEVC GMAFHHSSVL RQHKRIHTGE KPYTCSECGT SFRQGSALIG
610 620 630 640 650
HKRVHTGEKP YECEECGKAF RVSSNLTGHK KRKHQVWSTH ELDGSRKSLS
660
PVTVSQTSVV SILTSA
Length:666
Mass (Da):76,322
Last modified:February 20, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i24407CFED3DE28E6
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAB16812 differs from that shown. Reason: Frameshift at positions 396 and 408.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_031136486R → C. Corresponds to variant dbSNP:rs9295783Ensembl.1
Natural variantiVAR_031137511K → Q1 PublicationCorresponds to variant dbSNP:rs6456880Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL662791 Genomic DNA No translation available.
AL662865 Genomic DNA No translation available.
AL929561 Genomic DNA No translation available.
BX293545 Genomic DNA No translation available.
CR759957 Genomic DNA No translation available.
BX927167 Genomic DNA No translation available.
CR759835 Genomic DNA No translation available.
BC136745 mRNA Translation: AAI36746.1
U71600 mRNA Translation: AAB16812.1 Frameshift.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS34357.1

NCBI Reference Sequences

More...
RefSeqi
NP_001010877.2, NM_001010877.3
NP_001305463.1, NM_001318534.1
XP_016866247.1, XM_017010758.1
XP_016866248.1, XM_017010759.1

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.148218

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000377179; ENSP00000366384; ENSG00000197935
ENST00000383655; ENSP00000373151; ENSG00000169260
ENST00000426120; ENSP00000398983; ENSG00000225351
ENST00000429714; ENSP00000399157; ENSG00000235178
ENST00000436574; ENSP00000405154; ENSG00000235589
ENST00000452316; ENSP00000415772; ENSG00000223687
ENST00000458265; ENSP00000398440; ENSG00000233831

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
282890

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:282890

UCSC genome browser

More...
UCSCi
uc003nlu.3 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL662791 Genomic DNA No translation available.
AL662865 Genomic DNA No translation available.
AL929561 Genomic DNA No translation available.
BX293545 Genomic DNA No translation available.
CR759957 Genomic DNA No translation available.
BX927167 Genomic DNA No translation available.
CR759835 Genomic DNA No translation available.
BC136745 mRNA Translation: AAI36746.1
U71600 mRNA Translation: AAB16812.1 Frameshift.
CCDSiCCDS34357.1
RefSeqiNP_001010877.2, NM_001010877.3
NP_001305463.1, NM_001318534.1
XP_016866247.1, XM_017010758.1
XP_016866248.1, XM_017010759.1
UniGeneiHs.148218

3D structure databases

ProteinModelPortaliQ5JNZ3
SMRiQ5JNZ3
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi129424, 5 interactors
IntActiQ5JNZ3, 1 interactor
STRINGi9606.ENSP00000366384

PTM databases

iPTMnetiQ5JNZ3
PhosphoSitePlusiQ5JNZ3

Polymorphism and mutation databases

BioMutaiZNF311
DMDMi143758539

Proteomic databases

jPOSTiQ5JNZ3
MaxQBiQ5JNZ3
PaxDbiQ5JNZ3
PeptideAtlasiQ5JNZ3
PRIDEiQ5JNZ3
ProteomicsDBi62993

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000377179; ENSP00000366384; ENSG00000197935
ENST00000383655; ENSP00000373151; ENSG00000169260
ENST00000426120; ENSP00000398983; ENSG00000225351
ENST00000429714; ENSP00000399157; ENSG00000235178
ENST00000436574; ENSP00000405154; ENSG00000235589
ENST00000452316; ENSP00000415772; ENSG00000223687
ENST00000458265; ENSP00000398440; ENSG00000233831
GeneIDi282890
KEGGihsa:282890
UCSCiuc003nlu.3 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
282890
DisGeNETi282890
EuPathDBiHostDB:ENSG00000197935.6

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ZNF311
HGNCiHGNC:13847 ZNF311
HPAiHPA050541
neXtProtiNX_Q5JNZ3
OpenTargetsiENSG00000197935
PharmGKBiPA134865305

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00940000163512
HOGENOMiHOG000234617
HOVERGENiHBG018163
InParanoidiQ5JNZ3
KOiK09228
OMAiEWQCLTH
OrthoDBi1318335at2759
PhylomeDBiQ5JNZ3
TreeFamiTF341635

Enzyme and pathway databases

ReactomeiR-HSA-212436 Generic Transcription Pathway

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
282890

Protein Ontology

More...
PROi
PR:Q5JNZ3

Gene expression databases

BgeeiENSG00000197935 Expressed in 123 organ(s), highest expression level in amniotic fluid
ExpressionAtlasiQ5JNZ3 baseline and differential
GenevisibleiQ5JNZ3 HS

Family and domain databases

CDDicd07765 KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 8 hits
SMARTiView protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 14 hits
SUPFAMiSSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 8 hits
PROSITEiView protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 14 hits
PS50157 ZINC_FINGER_C2H2_2, 14 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN311_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5JNZ3
Secondary accession number(s): A2BFK5, B0S7Y4, Q92971
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 3, 2007
Last sequence update: February 20, 2007
Last modified: February 13, 2019
This is version 130 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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