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UniProtKB - Q5JH47 (RNP3_THEKO)
Protein
Ribonuclease P protein component 3
Gene
rnp3
Organism
Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1))
Status
Functioni
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
UniRule annotationCatalytic activityi
- Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation EC:3.1.26.5
GO - Molecular functioni
- ribonuclease P activity Source: UniProtKB-UniRule
- RNA binding Source: GO_Central
GO - Biological processi
- tRNA 5'-leader removal Source: UniProtKB-UniRule
Keywordsi
Molecular function | Endonuclease, Hydrolase, Nuclease |
Biological process | tRNA processing |
Names & Taxonomyi
Protein namesi | Recommended name: Ribonuclease P protein component 3UniRule annotation (EC:3.1.26.5UniRule annotation)Short name: RNase P component 3UniRule annotation Alternative name(s): Rpp30UniRule annotation |
Gene namesi | Name:rnp3UniRule annotation Ordered Locus Names:TK1450 |
Organismi | Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1)) |
Taxonomic identifieri | 69014 [NCBI] |
Taxonomic lineagei | Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Thermococcus › |
Proteomesi |
|
Subcellular locationi
Cytoplasm and Cytosol
- Cytoplasm UniRule annotation
Other locations
- cytoplasm Source: UniProtKB-SubCell
- ribonuclease P complex Source: UniProtKB-UniRule
Keywords - Cellular componenti
CytoplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000140047 | 1 – 220 | Ribonuclease P protein component 3Add BLAST | 220 |
Interactioni
Subunit structurei
Consists of a catalytic RNA component and at least 4-5 protein subunits.
UniRule annotationProtein-protein interaction databases
STRINGi | 69014.TK1450 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | Q5JH47 |
ModBasei | Search... |
PDBe-KBi | Search... |
Family & Domainsi
Sequence similaritiesi
Belongs to the eukaryotic/archaeal RNase P protein component 3 family.UniRule annotation
Phylogenomic databases
eggNOGi | arCOG00307, Archaea |
HOGENOMi | CLU_1302679_0_0_2 |
InParanoidi | Q5JH47 |
OMAi | WFDEVVF |
OrthoDBi | 66325at2157 |
PhylomeDBi | Q5JH47 |
Family and domain databases
HAMAPi | MF_00756, RNase_P_3, 1 hit |
InterProi | View protein in InterPro IPR016195, Pol/histidinol_Pase-like IPR023539, RNase_P_comp-3_arc IPR002738, RNase_P_p30 |
Pfami | View protein in Pfam PF01876, RNase_P_p30, 1 hit |
SUPFAMi | SSF89550, SSF89550, 1 hit |
i Sequence
Sequence statusi: Complete.
Q5JH47-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSEEEVSFSR DYFVEMDVRD EEAHELASDW FDEVVFTKKL VLEDPPDWGS
60 70 80 90 100
LKEELKELRG KYGKVALLLV TRKPSLIREV KSRNLKALLY VQGGDMRINR
110 120 130 140 150
MAIESGVDAL ISPWFGRKDP GFDHTLAGMA ARRGVAIGFS LSPLLNANPY
160 170 180 190 200
GRAQILRFMM KTWQLVKKYR VPRFITSSAE SRWEVRGPRD LMSLGINIGM
210 220
EIPEARASLN FYPRTIVWKL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AP006878 Genomic DNA Translation: BAD85639.1 |
RefSeqi | WP_011250401.1, NC_006624.1 |
Genome annotation databases
EnsemblBacteriai | BAD85639; BAD85639; TK1450 |
GeneIDi | 3235810 |
KEGGi | tko:TK1450 |
PATRICi | fig|69014.16.peg.1412 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AP006878 Genomic DNA Translation: BAD85639.1 |
RefSeqi | WP_011250401.1, NC_006624.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
3WYZ | X-ray | 2.21 | A | 1-220 | [»] | |
3WZ0 | X-ray | 2.79 | E/F | 1-220 | [»] | |
SMRi | Q5JH47 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
STRINGi | 69014.TK1450 |
Genome annotation databases
EnsemblBacteriai | BAD85639; BAD85639; TK1450 |
GeneIDi | 3235810 |
KEGGi | tko:TK1450 |
PATRICi | fig|69014.16.peg.1412 |
Phylogenomic databases
eggNOGi | arCOG00307, Archaea |
HOGENOMi | CLU_1302679_0_0_2 |
InParanoidi | Q5JH47 |
OMAi | WFDEVVF |
OrthoDBi | 66325at2157 |
PhylomeDBi | Q5JH47 |
Family and domain databases
HAMAPi | MF_00756, RNase_P_3, 1 hit |
InterProi | View protein in InterPro IPR016195, Pol/histidinol_Pase-like IPR023539, RNase_P_comp-3_arc IPR002738, RNase_P_p30 |
Pfami | View protein in Pfam PF01876, RNase_P_p30, 1 hit |
SUPFAMi | SSF89550, SSF89550, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | RNP3_THEKO | |
Accessioni | Q5JH47Primary (citable) accession number: Q5JH47 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | August 30, 2005 |
Last sequence update: | February 15, 2005 | |
Last modified: | February 23, 2022 | |
This is version 88 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families