Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 61 (12 Aug 2020)
Sequence version 1 (03 Oct 2012)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein
Submitted name:

Selectin-like protein

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandLectinImported

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Selectin-like proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 17Sequence analysisAdd BLAST17
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500425745118 – 3574Sequence analysisAdd BLAST3557

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi406 ↔ 433PROSITE-ProRule annotation
Disulfide bondi466 ↔ 493PROSITE-ProRule annotation
Disulfide bondi1219 ↔ 1228PROSITE-ProRule annotation
Disulfide bondi1257 ↔ 1266PROSITE-ProRule annotation
Disulfide bondi1295 ↔ 1304PROSITE-ProRule annotation
Disulfide bondi1333 ↔ 1342PROSITE-ProRule annotation
Disulfide bondi1371 ↔ 1380PROSITE-ProRule annotation
Disulfide bondi1409 ↔ 1418PROSITE-ProRule annotation
Disulfide bondi1661 ↔ 1688PROSITE-ProRule annotation
Disulfide bondi1719 ↔ 1746PROSITE-ProRule annotation
Disulfide bondi1818 ↔ 1845PROSITE-ProRule annotation
Disulfide bondi1876 ↔ 1903PROSITE-ProRule annotation
Disulfide bondi1934 ↔ 1961PROSITE-ProRule annotation
Disulfide bondi1992 ↔ 2019PROSITE-ProRule annotation
Disulfide bondi2086 ↔ 2129PROSITE-ProRule annotation
Disulfide bondi2175 ↔ 2202PROSITE-ProRule annotation
Disulfide bondi2352 ↔ 2379PROSITE-ProRule annotation
Disulfide bondi2411 ↔ 2438PROSITE-ProRule annotation
Disulfide bondi2469 ↔ 2496PROSITE-ProRule annotation
Disulfide bondi2527 ↔ 2554PROSITE-ProRule annotation
Disulfide bondi2688 ↔ 2715PROSITE-ProRule annotation
Disulfide bondi2746 ↔ 2773PROSITE-ProRule annotation
Disulfide bondi2804 ↔ 2831PROSITE-ProRule annotation
Disulfide bondi2862 ↔ 2889PROSITE-ProRule annotation
Disulfide bondi2920 ↔ 2947PROSITE-ProRule annotation
Disulfide bondi2978 ↔ 3005PROSITE-ProRule annotation
Disulfide bondi3035 ↔ 3062PROSITE-ProRule annotation
Disulfide bondi3093 ↔ 3120PROSITE-ProRule annotation
Disulfide bondi3270 ↔ 3297PROSITE-ProRule annotation
Disulfide bondi3328 ↔ 3355PROSITE-ProRule annotation
Disulfide bondi3387 ↔ 3414PROSITE-ProRule annotation
Disulfide bondi3507 ↔ 3517PROSITE-ProRule annotation
Disulfide bondi3525 ↔ 3534PROSITE-ProRule annotation
Disulfide bondi3539 ↔ 3549PROSITE-ProRule annotation
Disulfide bondi3557 ↔ 3566PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationARBA annotation

Proteomic databases

PeptideAtlas

More...
PeptideAtlasi
Q5JB40

PRoteomics IDEntifications database

More...
PRIDEi
Q5JB40

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini83 – 264VWFAInterPro annotationAdd BLAST182
Domaini376 – 435SushiInterPro annotationAdd BLAST60
Domaini436 – 495SushiInterPro annotationAdd BLAST60
Domaini496 – 561SushiInterPro annotationAdd BLAST66
Domaini560 – 642HYRInterPro annotationAdd BLAST83
Domaini643 – 724HYRInterPro annotationAdd BLAST82
Domaini725 – 789SushiInterPro annotationAdd BLAST65
Domaini1193 – 1229EGF-likeInterPro annotationAdd BLAST37
Domaini1231 – 1267EGF-likeInterPro annotationAdd BLAST37
Domaini1269 – 1305EGF-likeInterPro annotationAdd BLAST37
Domaini1307 – 1343EGF-likeInterPro annotationAdd BLAST37
Domaini1345 – 1381EGF-likeInterPro annotationAdd BLAST37
Domaini1383 – 1419EGF-likeInterPro annotationAdd BLAST37
Domaini1632 – 1690SushiInterPro annotationAdd BLAST59
Domaini1691 – 1748SushiInterPro annotationAdd BLAST58
Domaini1748 – 1787EGF-likeInterPro annotationAdd BLAST40
Domaini1790 – 1847SushiInterPro annotationAdd BLAST58
Domaini1848 – 1905SushiInterPro annotationAdd BLAST58
Domaini1906 – 1963SushiInterPro annotationAdd BLAST58
Domaini1964 – 2021SushiInterPro annotationAdd BLAST58
Domaini2022 – 2083SushiInterPro annotationAdd BLAST62
Domaini2084 – 2146SushiInterPro annotationAdd BLAST63
Domaini2147 – 2204SushiInterPro annotationAdd BLAST58
Domaini2205 – 2264SushiInterPro annotationAdd BLAST60
Domaini2265 – 2323SushiInterPro annotationAdd BLAST59
Domaini2324 – 2381SushiInterPro annotationAdd BLAST58
Domaini2382 – 2440SushiInterPro annotationAdd BLAST59
Domaini2441 – 2498SushiInterPro annotationAdd BLAST58
Domaini2499 – 2556SushiInterPro annotationAdd BLAST58
Domaini2557 – 2613SushiInterPro annotationAdd BLAST57
Domaini2666 – 2717SushiInterPro annotationAdd BLAST52
Domaini2718 – 2775SushiInterPro annotationAdd BLAST58
Domaini2776 – 2833SushiInterPro annotationAdd BLAST58
Domaini2834 – 2891SushiInterPro annotationAdd BLAST58
Domaini2892 – 2949SushiInterPro annotationAdd BLAST58
Domaini2950 – 3007SushiInterPro annotationAdd BLAST58
Domaini3008 – 3064SushiInterPro annotationAdd BLAST57
Domaini3065 – 3122SushiInterPro annotationAdd BLAST58
Domaini3123 – 3181SushiInterPro annotationAdd BLAST59
Domaini3182 – 3241SushiInterPro annotationAdd BLAST60
Domaini3242 – 3299SushiInterPro annotationAdd BLAST58
Domaini3300 – 3357SushiInterPro annotationAdd BLAST58
Domaini3358 – 3416SushiInterPro annotationAdd BLAST59
Domaini3417 – 3473SushiInterPro annotationAdd BLAST57
Domaini3503 – 3535EGF-likeInterPro annotationAdd BLAST33
Domaini3536 – 3567EGF-likeInterPro annotationAdd BLAST32

Keywords - Domaini

EGF-like domainPROSITE-ProRule annotationARBA annotation, RepeatARBA annotation, SignalSequence analysisARBA annotation, SushiPROSITE-ProRule annotationARBA annotation

Phylogenomic databases

KEGG Orthology (KO)

More...
KOi
K17495

Database of Orthologous Groups

More...
OrthoDBi
46968at2759

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00033, CCP, 32 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.50.410, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR013320, ConA-like_dom_sf
IPR001881, EGF-like_Ca-bd_dom
IPR013032, EGF-like_CS
IPR000742, EGF-like_dom
IPR000152, EGF-type_Asp/Asn_hydroxyl_site
IPR018097, EGF_Ca-bd_CS
IPR009030, Growth_fac_rcpt_cys_sf
IPR003410, HYR_dom
IPR001759, Pentraxin-related
IPR035976, Sushi/SCR/CCP_sf
IPR000436, Sushi_SCR_CCP_dom
IPR011641, Tyr-kin_ephrin_A/B_rcpt-like
IPR002035, VWF_A
IPR036465, vWFA_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00008, EGF, 6 hits
PF07645, EGF_CA, 1 hit
PF07699, Ephrin_rec_like, 4 hits
PF12661, hEGF, 1 hit
PF02494, HYR, 2 hits
PF00354, Pentaxin, 1 hit
PF00084, Sushi, 33 hits
PF00092, VWA, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00895, PENTAXIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00032, CCP, 34 hits
SM00181, EGF, 11 hits
SM00179, EGF_CA, 8 hits
SM01411, Ephrin_rec_like, 4 hits
SM00159, PTX, 1 hit
SM00327, VWA, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49899, SSF49899, 1 hit
SSF53300, SSF53300, 1 hit
SSF57184, SSF57184, 3 hits
SSF57535, SSF57535, 33 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00010, ASX_HYDROXYL, 6 hits
PS00022, EGF_1, 8 hits
PS01186, EGF_2, 7 hits
PS50026, EGF_3, 9 hits
PS01187, EGF_CA, 3 hits
PS50825, HYR, 2 hits
PS51828, PTX_2, 1 hit
PS50923, SUSHI, 34 hits
PS50234, VWFA, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q5JB40-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MWPRLAFCCW GLALVSGWAT FQQMSPSRNF SFRLFPETAP GAPGSIPAPP
60 70 80 90 100
APGDEAAGSR VERLGQAFRR RVRLLRELSE RLELVFLVDD SSSVGEVNFR
110 120 130 140 150
SELMFVRKLL SDFPVVPTAT RVAIVTFSSK NYVVPRVDYI STRRARQHKC
160 170 180 190 200
ALLLQEIPAI SYRGGGTYTK GAFQQAAQIL LHARENSTKV VFLITDGYSN
210 220 230 240 250
GGDPRPIAAS LRDSGVEIFT FGIWQGNIRE LNDMASTPKE EHCYLLHSFE
260 270 280 290 300
EFEALARRAL HEDLPSGSFI QDDMVHCSYL CDEGKDCCDR MGSCKCGTHT
310 320 330 340 350
GHFECICEKG YYGKGLQYEC TACPSGTYKP EGSPGGISSC IPCPDENHTS
360 370 380 390 400
PPGSTSPEDC VCREGYRASG QTCELVHCPA LKPPENGYFI QNTCNNHFNA
410 420 430 440 450
ACGVRCHPGF DLVGSSIILC LPNGLWSGLE SYCRVRTCPH LRQPKHGHIS
460 470 480 490 500
CSTREMLYKT TCLVACDEGY RLEGSDKLTC QGNSQWDGPE PRCVERHCST
510 520 530 540 550
FQMPKDVIIS PHNCGKQPAK FGTICYVSCR QGFILSGVKE MLRCTTSGKW
560 570 580 590 600
NVGVQAAVCK DVEAPQINCP KDIEAKTLEQ QDSANVTWQI PTAKDNSGEK
610 620 630 640 650
VSVHVHPAFT PPYLFPIGDV AIVYTATDLS GNQASCIFHI KVIDAEPPVI
660 670 680 690 700
DWCRSPPPVQ VSEKVHAASW DEPQFSDNSG AELVITRSHT QGDLFPQGET
710 720 730 740 750
IVQYTATDPS GNNRTCDIHI VIKGSPCEIP FTPVNGDFIC TPDNTGVNCT
760 770 780 790 800
LTCLEGYDFT EGSTDKYYCA YEDGVWKPTY TTEWPDCAKK RFANHGFKSF
810 820 830 840 850
EMFYKAARCD DTDLMKKFSE AFETTLGKMV PSFCSDAEDI DWRLEENLTK
860 870 880 890 900
KYCLEYNYDY ENGFAIGPGG WGAANRLDYS YDDFLDTVQE TATSIGNAKS
910 920 930 940 950
SRIKRSAPLS DYKIKLIFNI TASVPLPDER NDTLEWENQQ RLLQTLETIT
960 970 980 990 1000
NKLKRTLNKD PMYSFQLASE ILIADSNSLG TKKASPFCRP GSVLRGRMCV
1010 1020 1030 1040 1050
NCPLGTYYNL EHFTCESCRI GSYQDEEGQL ECKLCPSGMY TEYIHSRNIS
1060 1070 1080 1090 1100
DCKAQCKQGT YSCSGLETCE SCPLGTYQPK FGSRSCLSCP ENTSTVKRGA
1110 1120 1130 1140 1150
VNISACGVPC PEGKFSRSGL MPCHPCPRDY YQPNAGKAFC LACPFYGTTP
1160 1170 1180 1190 1200
FAGSRSITEC SSFSSTFSAA EESVVPPASL GHIKKRHEIS SQVFHECFFN
1210 1220 1230 1240 1250
PCHNSGTCQQ LGRGYVCLCP LGYTGLKCET DIDECSPLPC LNNGVCKDLV
1260 1270 1280 1290 1300
GEFICECPSG YTGQRCEENI NECSSSPCLN KGICVDGVAG YRCTCVKGFV
1310 1320 1330 1340 1350
GLHCETEVNE CQSNPCLNNA VCEDQVGGFL CKCPPGFLGT RCGKNVDECL
1360 1370 1380 1390 1400
SQPCKNGATC KDGANSFRCL CAAGFTGSHC ELNINECQSN PCRNQATCVD
1410 1420 1430 1440 1450
ELNSYSCKCQ PGFSGKRCET EQSTGFNLDF EVSGIYGYVM LVGMLPSLHA
1460 1470 1480 1490 1500
LTCTFWMKSS DDMNYGTPIS YAVDNGSDNT LLLTDYNGWV LYVNGREKIT
1510 1520 1530 1540 1550
NCPSVNDGRW HHIAITWTSA NGIWKVYIDG KLSDGGAGLS VGLPIPGMFG
1560 1570 1580 1590 1600
GGALVLGQEQ DKKGEGFSPA ESFVGSISQL NLWDYVLSPQ QVKSLATSCP
1610 1620 1630 1640 1650
EELSKGNVLA WPDFLSGIVG KVKIDSKSIF CSDCPRLGGS VPHLRTASED
1660 1670 1680 1690 1700
LKPGSKVNLF CDPGFQLVGN PVQYCLNQGQ WTQPLPHCER ISCGVPPPLE
1710 1720 1730 1740 1750
NGFHSADDFY AGSTVTYQCN NGYYLLGDSR MFCTDNGSWN GVSPSCLDVD
1760 1770 1780 1790 1800
ECAVGSDCSE HASCLNVDGS YICSCVPSYT GDGKNCAEPI KCKAPGNPEN
1810 1820 1830 1840 1850
GHSSGEIYTV GAEVTFSCQE GYQLMGVTKI TCLESGEWNH LIPYCKAVSC
1860 1870 1880 1890 1900
GKPAIPENGC IEELAFTFGS KVTYRCNKGY TLAGDKESSC LANSSWSHSP
1910 1920 1930 1940 1950
PVCEPVKCSS PENINNGKYI LSGLTYLSTA SYSCDTGYSL QGPSIIECTA
1960 1970 1980 1990 2000
SGIWDRAPPA CHLVFCGEPP AIKDAVITGN NFTFRNTVTY TCKEGYTLAG
2010 2020 2030 2040 2050
LDTIECLADG KWSRSDQQCL AVSCDEPPIV DHASPETAHR LFGDIAFYYC
2060 2070 2080 2090 2100
SDGYSLADNS QLLCNAQGKW VPPEGQDMPR CIAHFCEKPP SVSYSILESV
2110 2120 2130 2140 2150
SKAKFAAGSV VSFKCMEGFV LNTSAKIECM RGGQWNPSPM SIQCIPVRCG
2160 2170 2180 2190 2200
EPPSIMNGYA SGSNYSFGAM VAYSCNKGFY IKGEKKSTCE ATGQWSSPIP
2210 2220 2230 2240 2250
TCHPVSCGEP PKVENGFLEH TTGRIFESEV RYQCNPGYKS VGSPVFVCQA
2260 2270 2280 2290 2300
NRHWHSESPL MCVPLDCGKP PPIQNGFMKG ENFEVGSKVQ FFCNEGYELV
2310 2320 2330 2340 2350
GDSSWTCQKS GKWNKKSNPK CMPAKCPEPP LLENQLVLKE LTTEVGVVTF
2360 2370 2380 2390 2400
SCKEGHVLQG PSVLKCLPSQ QWNDSFPVCK IVLCTPPPLI SFGVPIPSSA
2410 2420 2430 2440 2450
LHFGSTVKYS CVGGFFLRGN STTLCQPDGT WSSPLPECVP VECPQPEEIP
2460 2470 2480 2490 2500
NGIIDVQGLA YLSTALYTCK PGFELVGNTT TLCGENGHWL GGKPTCKAIE
2510 2520 2530 2540 2550
CLKPKEILNG KFSYTDLHYG QTVTYSCNRG FRLEGPSALT CLETGDWDVD
2560 2570 2580 2590 2600
APSCNAIHCD SPQPIENGFV EGADYSYGAI IIYSCFPGFQ VAGHAMQTCE
2610 2620 2630 2640 2650
ESGWSSSIPT CMPIDCGLPP HIDFGDCTKL KDDQGYFEQE DDMMEVPYVT
2660 2670 2680 2690 2700
PHPPYHLGAV AKTWENTKES PATHSSNFLY GTMVSYTCNP GYELLGNPVL
2710 2720 2730 2740 2750
ICQEDGTWNG SAPSCISIEC DLPTAPENGF LRFTETSMGS AVQYSCKPGH
2760 2770 2780 2790 2800
ILAGSDLRLC LENRKWSGAS PRCEAISCKK PNPVMNGSIK GSNYTYLSTL
2810 2820 2830 2840 2850
YYECDPGYVL NGTERRTCQD DKNWDEDEPI CIPVDCSSPP VSANGQVRGD
2860 2870 2880 2890 2900
EYTFQKEIEY TCNEGFLLEG ARSRVCLANG SWSGATPDCV PVRCATPPQL
2910 2920 2930 2940 2950
ANGVTEGLDY GFMKEVTFHC HEGYILHGAP KLTCQSDGNW DAEIPLCKPV
2960 2970 2980 2990 3000
NCGPPEDLAH GFPNGFSFIH GGHIQYQCFP GYKLHGNSSR RCLSNGSWSG
3010 3020 3030 3040 3050
SSPSCLPCRC STPVIEYGTV NGTDFDCGKA ARIQCFKGFK LLGLSEITCE
3060 3070 3080 3090 3100
ADGQWSSGFP HCEHTSCGSL PMIPNAFISE TSSWKENVIT YSCRSGYVIQ
3110 3120 3130 3140 3150
GSSDLICTEK GVWSQPYPVC EPLSCGSPPS VANAVATGEA HTYESEVKLR
3160 3170 3180 3190 3200
CLEGYTMDTD TDTFTCQKDG RWFPERISCS PKKCPLPENI THILVHGDDF
3210 3220 3230 3240 3250
SVNRQVSVSC AEGYTFEGVN ISVCQLDGTW EPPFSDESCS PVSCGKPESP
3260 3270 3280 3290 3300
EHGFVVGSKY TFESTIIYQC EPGYELEGNR ERVCQENRQW SGGVAICKET
3310 3320 3330 3340 3350
RCETQLEFLN GKADIENRTT GPNVVYSCNR GYSLEGPSEA HCTENGTWSH
3360 3370 3380 3390 3400
PVPLCKPNPC PVPFVIPENA LLSEKEFYVD QNVSIKCREG FLLQGHGIIT
3410 3420 3430 3440 3450
YNPDETWTQT SAKCEKISCG PPAHVENAIA RGVHYQYGDM ITYSCYSGYM
3460 3470 3480 3490 3500
LEGFLRSVCL ENGTWTSPPI CRAVCRFPCQ NGGICQRPNA CSCPEGWMGR
3510 3520 3530 3540 3550
LCEEPICILP CLNGGRCVAP YQCDCPPGWT GSRCHTAVCQ SPCLNGGKCV
3560 3570
RPNRCHCLSS WTGHNCSRKR RTGF
Length:3,574
Mass (Da):390,548
Last modified:October 3, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i74C9E9C57527DF23
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY243503 mRNA Translation: AAQ89957.1

NCBI Reference Sequences

More...
RefSeqi
NP_699197.3, NM_153366.3

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
79987

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:79987

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY243503 mRNA Translation: AAQ89957.1
RefSeqiNP_699197.3, NM_153366.3

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Proteomic databases

PeptideAtlasiQ5JB40
PRIDEiQ5JB40

Genome annotation databases

GeneIDi79987
KEGGihsa:79987

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
79987

Phylogenomic databases

KOiK17495
OrthoDBi46968at2759

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
79987, 4 hits in 869 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
79987

Family and domain databases

CDDicd00033, CCP, 32 hits
Gene3Di3.40.50.410, 1 hit
InterProiView protein in InterPro
IPR013320, ConA-like_dom_sf
IPR001881, EGF-like_Ca-bd_dom
IPR013032, EGF-like_CS
IPR000742, EGF-like_dom
IPR000152, EGF-type_Asp/Asn_hydroxyl_site
IPR018097, EGF_Ca-bd_CS
IPR009030, Growth_fac_rcpt_cys_sf
IPR003410, HYR_dom
IPR001759, Pentraxin-related
IPR035976, Sushi/SCR/CCP_sf
IPR000436, Sushi_SCR_CCP_dom
IPR011641, Tyr-kin_ephrin_A/B_rcpt-like
IPR002035, VWF_A
IPR036465, vWFA_dom_sf
PfamiView protein in Pfam
PF00008, EGF, 6 hits
PF07645, EGF_CA, 1 hit
PF07699, Ephrin_rec_like, 4 hits
PF12661, hEGF, 1 hit
PF02494, HYR, 2 hits
PF00354, Pentaxin, 1 hit
PF00084, Sushi, 33 hits
PF00092, VWA, 1 hit
PRINTSiPR00895, PENTAXIN
SMARTiView protein in SMART
SM00032, CCP, 34 hits
SM00181, EGF, 11 hits
SM00179, EGF_CA, 8 hits
SM01411, Ephrin_rec_like, 4 hits
SM00159, PTX, 1 hit
SM00327, VWA, 1 hit
SUPFAMiSSF49899, SSF49899, 1 hit
SSF53300, SSF53300, 1 hit
SSF57184, SSF57184, 3 hits
SSF57535, SSF57535, 33 hits
PROSITEiView protein in PROSITE
PS00010, ASX_HYDROXYL, 6 hits
PS00022, EGF_1, 8 hits
PS01186, EGF_2, 7 hits
PS50026, EGF_3, 9 hits
PS01187, EGF_CA, 3 hits
PS50825, HYR, 2 hits
PS51828, PTX_2, 1 hit
PS50923, SUSHI, 34 hits
PS50234, VWFA, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ5JB40_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5JB40
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: October 3, 2012
Last modified: August 12, 2020
This is version 61 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again