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UniProtKB - Q5J8X5 (M4A13_HUMAN)

Entry version 104 (23 Feb 2022)
Sequence version 2 (31 May 2011)
Previous versions | rss
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Protein

Membrane-spanning 4-domains subfamily A member 13

Gene

MS4A13

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in signal transduction as a component of a multimeric receptor complex.

By similarity

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q5J8X5

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		Q5J8X5

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Membrane-spanning 4-domains subfamily A member 13
Alternative name(s):
Testis-expressed transmembrane protein 4
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MS4A13
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 11

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:16674, MS4A13

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q5J8X5

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000204979

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei1 – 21HelicalSequence analysisAdd BLAST21
Transmembranei32 – 52HelicalSequence analysisAdd BLAST21
Transmembranei66 – 86HelicalSequence analysisAdd BLAST21
Transmembranei111 – 131HelicalSequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...OpenTargetsi		ENSG00000204979

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA142671314

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q5J8X5, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		MS4A13

Domain mapping of disease mutations (DMDM)

More...DMDMi		334302831

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003150551 – 152Membrane-spanning 4-domains subfamily A member 13Add BLAST152

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q5J8X5

PeptideAtlas

More...PeptideAtlasi		Q5J8X5

PRoteomics IDEntifications database

More...PRIDEi		Q5J8X5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000204979, Expressed in left testis and 12 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q5J8X5, baseline and differential

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000204979, Tissue enriched (testis)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Q5J8X5
With#Exp.IntAct
AQP2 [P41181]3EBI-12070086,EBI-12701138
AQP6 [Q13520]3EBI-12070086,EBI-13059134
ASGR2 - isoform 3 [P07307-3]3EBI-12070086,EBI-12808270
ATP6V0E1 [O15342]3EBI-12070086,EBI-12935759
BEST1 - isoform 4 [O76090-4]3EBI-12070086,EBI-18631885
BIK [Q13323]3EBI-12070086,EBI-700794
CBARP - isoform 2 [Q8N350-4]3EBI-12070086,EBI-19051169
CD79A [P11912]3EBI-12070086,EBI-7797864
CLDN7 [O95471]3EBI-12070086,EBI-740744
CREB3L1 [Q96BA8]3EBI-12070086,EBI-6942903
CREB3L3 [Q68CJ9]3EBI-12070086,EBI-852194
DAGLA [Q9Y4D2]3EBI-12070086,EBI-12808806
EBP [Q15125]3EBI-12070086,EBI-3915253
EDA [Q92838]3EBI-12070086,EBI-529425
EREG [O14944]3EBI-12070086,EBI-17272224
ERGIC3 [Q9Y282]3EBI-12070086,EBI-781551
EVA1A [Q9H8M9]3EBI-12070086,EBI-715362
FAM209A [Q5JX71]3EBI-12070086,EBI-18304435
FAM210B [Q96KR6]3EBI-12070086,EBI-18938272
FFAR2 [O15552]3EBI-12070086,EBI-2833872
GJA4 [P35212]3EBI-12070086,EBI-6918707
GJA5 [P36382]3EBI-12070086,EBI-750433
GJA8 [P48165]3EBI-12070086,EBI-17458373
GJB1 [P08034]3EBI-12070086,EBI-17565645
GJB5 [O95377]3EBI-12070086,EBI-3909454
GJB6 [O95452]3EBI-12070086,EBI-13345609
GJC3 [Q8NFK1]3EBI-12070086,EBI-20110678
GPR152 [Q8TDT2]3EBI-12070086,EBI-13345167
HERPUD2 [Q9BSE4]3EBI-12070086,EBI-2868124
JSRP1 [Q96MG2]3EBI-12070086,EBI-11305455
KCNMB4 [Q86W47]3EBI-12070086,EBI-19112227
KLRC1 [P26715]3EBI-12070086,EBI-9018187
LHFPL5 [Q8TAF8]3EBI-12070086,EBI-2820517
LRRC3B [Q96PB8]3EBI-12070086,EBI-17775622
MMGT1 [Q8N4V1]3EBI-12070086,EBI-6163737
MS4A3 [Q96HJ5]3EBI-12070086,EBI-12806656
NPDC1 [Q9NQX5]3EBI-12070086,EBI-748927
ODF4 [Q2M2E3]3EBI-12070086,EBI-12382569
POMK [Q9H5K3]3EBI-12070086,EBI-11337900
RAMP1 [O60894]3EBI-12070086,EBI-962893
RHCG [Q9UBD6]3EBI-12070086,EBI-15853497
RNF185 [Q96GF1]3EBI-12070086,EBI-2340249
SCN3B [Q9NY72]3EBI-12070086,EBI-17247926
SLC12A7 - isoform 2 [Q9Y666-2]3EBI-12070086,EBI-12854384
SLC13A4 [Q9UKG4]3EBI-12070086,EBI-12808018
SLC18A1 - isoform 3 [P54219-3]3EBI-12070086,EBI-17595455
SLC30A2 [Q9BRI3]6EBI-12070086,EBI-8644112
SLC39A2 [Q9NP94]3EBI-12070086,EBI-12898013
SLC7A1 [P30825]3EBI-12070086,EBI-4289564
SPAG4 [Q9NPE6]3EBI-12070086,EBI-10819434
SSMEM1 [Q8WWF3]3EBI-12070086,EBI-17280858
TBXA2R [Q0VAB0]3EBI-12070086,EBI-18271435
TLCD4 [Q96MV1]3EBI-12070086,EBI-12947623
TM4SF18 [Q96CE8]3EBI-12070086,EBI-13351685
TMC4 - isoform 3 [Q7Z404-3]3EBI-12070086,EBI-23725088
TMEM14B [Q9NUH8]3EBI-12070086,EBI-8638294
TMEM237 - isoform 2 [Q96Q45-2]3EBI-12070086,EBI-10982110
TMEM52B [Q4KMG9]3EBI-12070086,EBI-18178701
TMEM74 [Q96NL1]3EBI-12070086,EBI-10292091
VSIR [Q9H7M9]3EBI-12070086,EBI-744988

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		139008, 61 interactors

Protein interaction database and analysis system

More...IntActi		Q5J8X5, 60 interactors

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q5J8X5, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q5J8X5

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the MS4A family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502RTZG, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000015662

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_144238_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q5J8X5

Identification of Orthologs from Complete Genome Data

More...OMAi		GCSLWGI

Database of Orthologous Groups

More...OrthoDBi		1515352at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q5J8X5

TreeFam database of animal gene trees

More...TreeFami		TF353242

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR007237, CD20-like
IPR030417, MS4A

The PANTHER Classification System

More...PANTHERi		PTHR23320, PTHR23320, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF04103, CD20, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q5J8X5-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <p><strong>What is the canonical sequence?</strong><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MIGIFHIFMW YFLLVLYMGQ IKGAFGTYEP VTYKTGCTLW GIFFIIAGVF 
        60         70         80         90        100
LIRVTKYPTR SGIISTLIIN IICIITTITA VTLTIIELSH FNSVSYRNYG 
       110        120        130        140        150
QAKLGREVSR ILLFFYGLEF SIALTHSIYS CSNLFRRQND LTSVTEEAES 

TP
Length:152
Mass (Da):17,307
Last modified:May 31, 2011 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i15E9C8DB4307E608
GO
Isoform 2 (identifier: Q5J8X5-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     63-102: Missing.

Show »
Length:112
Mass (Da):12,901
Checksum:i8B486211D984B142
GO
Isoform 3 (identifier: Q5J8X5-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     44-102: Missing.

Show »
Length:93
Mass (Da):10,781
Checksum:iF9ECFBC47ED067F8
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9PPG1E9PPG1_HUMAN
Membrane-spanning 4-domains subfami...
MS4A13
61Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti102A → V in AAQ94112 (Ref. 1) Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_0621243G → D. Corresponds to variant dbSNP:rs55756397Ensembl.1
Natural variantiVAR_0621257I → V1 PublicationCorresponds to variant dbSNP:rs10736706Ensembl.1
Natural variantiVAR_05765458P → L. Corresponds to variant dbSNP:rs6591595Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_03047744 – 102Missing in isoform 3. 1 PublicationAdd BLAST59
Alternative sequenceiVSP_03047663 – 102Missing in isoform 2. 1 PublicationAdd BLAST40

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AY324188 mRNA Translation: AAQ94112.1
AY324189 mRNA Translation: AAQ94113.1
AY324190 mRNA Translation: AAQ94114.1
AP001034 Genomic DNA No translation available.
BC140799 mRNA Translation: AAI40800.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS31571.1 [Q5J8X5-1]
CCDS41653.1 [Q5J8X5-2]
CCDS60801.1 [Q5J8X5-3]

NCBI Reference Sequences

More...RefSeqi		NP_001012417.2, NM_001012417.2 [Q5J8X5-1]
NP_001094379.1, NM_001100909.1 [Q5J8X5-2]
NP_001265249.1, NM_001278320.1 [Q5J8X5-3]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000378185; ENSP00000367427; ENSG00000204979 [Q5J8X5-2]
ENST00000378186; ENSP00000367428; ENSG00000204979
ENST00000437058; ENSP00000415535; ENSG00000204979 [Q5J8X5-3]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		503497

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:503497

Matched Annotation from NCBI and EMBL-EBI (MANE) - Phase one

More...MANE-Selecti		ENST00000378186.7; ENSP00000367428.2; NM_001012417.3; NP_001012417.2

UCSC genome browser

More...UCSCi		uc001nps.4, human [Q5J8X5-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY324188 mRNA Translation: AAQ94112.1
AY324189 mRNA Translation: AAQ94113.1
AY324190 mRNA Translation: AAQ94114.1
AP001034 Genomic DNA No translation available.
BC140799 mRNA Translation: AAI40800.1
CCDSiCCDS31571.1 [Q5J8X5-1]
CCDS41653.1 [Q5J8X5-2]
CCDS60801.1 [Q5J8X5-3]
RefSeqiNP_001012417.2, NM_001012417.2 [Q5J8X5-1]
NP_001094379.1, NM_001100909.1 [Q5J8X5-2]
NP_001265249.1, NM_001278320.1 [Q5J8X5-3]

3D structure databases

SMRiQ5J8X5
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi139008, 61 interactors
IntActiQ5J8X5, 60 interactors

Genetic variation databases

BioMutaiMS4A13
DMDMi334302831

Proteomic databases

PaxDbiQ5J8X5
PeptideAtlasiQ5J8X5
PRIDEiQ5J8X5

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		50523, 58 antibodies from 13 providers

The DNASU plasmid repository

More...DNASUi		503497

Genome annotation databases

EnsembliENST00000378185; ENSP00000367427; ENSG00000204979 [Q5J8X5-2]
ENST00000378186; ENSP00000367428; ENSG00000204979
ENST00000437058; ENSP00000415535; ENSG00000204979 [Q5J8X5-3]
GeneIDi503497
KEGGihsa:503497
MANE-SelectiENST00000378186.7; ENSP00000367428.2; NM_001012417.3; NP_001012417.2
UCSCiuc001nps.4, human [Q5J8X5-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		503497

GeneCards: human genes, protein and diseases

More...GeneCardsi		MS4A13
HGNCiHGNC:16674, MS4A13
HPAiENSG00000204979, Tissue enriched (testis)
neXtProtiNX_Q5J8X5
OpenTargetsiENSG00000204979
PharmGKBiPA142671314
VEuPathDBiHostDB:ENSG00000204979

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG502RTZG, Eukaryota
GeneTreeiENSGT00390000015662
HOGENOMiCLU_144238_0_0_1
InParanoidiQ5J8X5
OMAiGCSLWGI
OrthoDBi1515352at2759
PhylomeDBiQ5J8X5
TreeFamiTF353242

Enzyme and pathway databases

PathwayCommonsiQ5J8X5
SignaLinkiQ5J8X5

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		503497, 2 hits in 957 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		MS4A13, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		503497
PharosiQ5J8X5, Tdark

Protein Ontology

More...PROi		PR:Q5J8X5
RNActiQ5J8X5, protein

Gene expression databases

BgeeiENSG00000204979, Expressed in left testis and 12 other tissues
ExpressionAtlasiQ5J8X5, baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR007237, CD20-like
IPR030417, MS4A
PANTHERiPTHR23320, PTHR23320, 1 hit
PfamiView protein in Pfam
PF04103, CD20, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiM4A13_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5J8X5
Secondary accession number(s): B2RTS9, Q5J8X3, Q5J8X4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: May 31, 2011
Last modified: February 23, 2022
This is version 104 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 11
    Human chromosome 11: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. SIMILARITY comments
    Index of protein domains and families
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