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Entry version 100 (18 Sep 2019)
Sequence version 1 (15 Feb 2005)
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Protein

mRNA decay activator protein ZFP36L3

Gene

Zfp36l3

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Placenta-specific zinc-finger RNA-binding protein that destabilizes cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis (PubMed:15814898, PubMed:26952984). Binds to the 3'-UTR ARE of placental target mRNAs, such as TNF, HBEGF and LIPG (PubMed:15814898, PubMed:18367448, PubMed:26952984). Involved in placental expression of many genes important for normal placental physiology (PubMed:26952984).3 Publications

Miscellaneous

Rodent-specific retrogene derived apparently from its related family member ZFP36L2 mRNA (PubMed:15814898, PubMed:26493225).2 Publications

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri122 – 150C3H1-type 1PROSITE-ProRule annotationAdd BLAST29
Zinc fingeri160 – 188C3H1-type 2PROSITE-ProRule annotationAdd BLAST29

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding, RNA-binding
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
mRNA decay activator protein ZFP36L3Curated
Alternative name(s):
Zinc finger protein 36, C3H1 type-like 3Imported
zinc finger protein 36-like 31 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Zfp36l31 PublicationImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:3525151 Zfp36l3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei380 – 400HelicalSequence analysisAdd BLAST21
Transmembranei420 – 440HelicalSequence analysisAdd BLAST21
Transmembranei441 – 461HelicalSequence analysisAdd BLAST21
Transmembranei468 – 488HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Cytoplasm, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Mice are viable and fertile, without apparent morphological or histological abnormalities in the placenta, but display a decrease in the numbers of surviving offspring. Display an abnormal accumulation of placental 3'UTR ARE-containing mRNAs. Exhibit also a decrease in ARE-containing mRNA decay in differentiated trophoblast stem cells.1 Publication

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi153R → A: Reduces ARE-containing RNA-binding. Loss of ARE-containing RNA-binding; when associated with A-157. 1 Publication1
Mutagenesisi157R → A: Reduces ARE-containing RNA-binding. Loss of ARE-containing RNA-binding; when associated with A-153. 1 Publication1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004235541 – 725mRNA decay activator protein ZFP36L3Add BLAST725

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q5ISE2

PeptideAtlas

More...
PeptideAtlasi
Q5ISE2

PRoteomics IDEntifications database

More...
PRIDEi
Q5ISE2

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q5ISE2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q5ISE2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in placenta and extraembryonic tissues (at protein level). Not detected in embryos and fetus (PubMed:15814898, PubMed:26952984).2 Publications

<p>This subsection of the ‘Expression’ section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified ‘at the protein level’.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed in placenta at 14.5 dpc. Expressed in the single layer of endodermal epithelial cells of the visceral yolk sac at 15.5 dpc (PubMed:26952984). Expressed in syncytiotrophoblast and trophoblast giant cells of the labyrinth region of the placenta at 17.5 dpc (PubMed:15814898, PubMed:26952984) (at protein level). Expressed specifically in extraembryonic structures, in placenta from 9.5 to 18.5 and yolk sac/amnion from 12.5 to 18.5 (PubMed:15814898, PubMed:26952984). Expressed in the labyrinthine layer of the trophoblastic placenta at 10.5, 12.5 and 14.5 dpc (PubMed:15814898). Expressed in syncytiotrophoblast and trophoblast giant cells, less in spongiotrophoblast cells, and not detected in maternal decidua or in allantois at 17.5 dpc (PubMed:26952984).2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000059334 Expressed in 9 organ(s), highest expression level in placenta

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q5ISE2

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000071630

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q5ISE2

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni193 – 711Necessary for cytoplasmic localization1 PublicationAdd BLAST519

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi340 – 648Ala-richAdd BLAST309
Compositional biasi694 – 699Poly-Ser6

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

Contains long series of C-terminal alanine-rich repeats that serve to maintain the protein in the cytoplasm.1 Publication

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri122 – 150C3H1-type 1PROSITE-ProRule annotationAdd BLAST29
Zinc fingeri160 – 188C3H1-type 2PROSITE-ProRule annotationAdd BLAST29

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1677 Eukaryota
COG5063 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155076

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000214117

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q5ISE2

Identification of Orthologs from Complete Genome Data

More...
OMAi
ITPRVAI

Database of Orthologous Groups

More...
OrthoDBi
1541140at2759

TreeFam database of animal gene trees

More...
TreeFami
TF315463

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011004 Trimer_LpxA-like_sf
IPR000571 Znf_CCCH
IPR036855 Znf_CCCH_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00642 zf-CCCH, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00356 ZnF_C3H1, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF51161 SSF51161, 1 hit
SSF90229 SSF90229, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50103 ZF_C3H1, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q5ISE2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MANNNLNRPL NTNVADSSNS SSTPGTAPPP SSSDPQVLGH QAPSSSASSL
60 70 80 90 100
TEDCSSSFAR DLNSYNNGQS GATGAVSWEA PHEPSEANAV SQIHPRNGEH
110 120 130 140 150
SLQQKPKPQK VSGSSSLATS ERYKTELCRP FEESGICKYG HKCQFAHGYR
160 170 180 190 200
ELRTLSRHPK YKTEPCRTFH SVGFCPYGTR CHFIHNQPEQ QPVLSESTLE
210 220 230 240 250
EPSSFNGSNV LHLGVNGEQQ PGLQSDSPSG FLSVNSQALQ APLQLNQQAL
260 270 280 290 300
SSGGVMPSSH PAAANLRMMC CRTSSSTTAH DADKDPDKDA DKDPSNNSAN
310 320 330 340 350
DALAFPQEPG DFSPVAFQNP NTATTTPTAF YNNQQQMGLA ASAQFQMPLA
360 370 380 390 400
RPLPSATIFG QASVGPALTP GAAMAPGAAL APAAALTPAA ALAPGAAMAL
410 420 430 440 450
GAAMATGAAM ATGAALTPGA ALALGAAMAA GAALAPGAAM APGAAMATGA
460 470 480 490 500
ALAFGAAMAT GTTLTPGAAM ALGAAMATGA ALAPGAAVAP RAALAPRAAF
510 520 530 540 550
APGAAALAPR AALPPGAALT PGAALAPGAA LAPRAALPPG ATLRPGAALI
560 570 580 590 600
PRAALAPGAA LAPGAALTPG AALAPGATLA PRAALAPGAA LAPRITITSR
610 620 630 640 650
AAITPGVAIA PGVATASTGI LAPGAATATV GNTSSTTITA ATAAEGAAPH
660 670 680 690 700
FTFQLPDVES ESESESLEFD VVTSTLDSLL VSDDEDEDDF LRRSSSSSSL
710 720
NESEFDNTNS SRRLPIFSRF SDSEK
Length:725
Mass (Da):72,346
Last modified:February 15, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD6FC9F4F92BAC37E
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY661338 mRNA Translation: AAV74249.1
AL691513 Genomic DNA No translation available.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS30138.1

NCBI Reference Sequences

More...
RefSeqi
NP_001009549.1, NM_001009549.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000071711; ENSMUSP00000071630; ENSMUSG00000059334

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
333473

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:333473

UCSC genome browser

More...
UCSCi
uc009tfk.1 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY661338 mRNA Translation: AAV74249.1
AL691513 Genomic DNA No translation available.
CCDSiCCDS30138.1
RefSeqiNP_001009549.1, NM_001009549.2

3D structure databases

SMRiQ5ISE2
ModBaseiSearch...

Protein-protein interaction databases

CORUMiQ5ISE2
STRINGi10090.ENSMUSP00000071630

PTM databases

iPTMnetiQ5ISE2
PhosphoSitePlusiQ5ISE2

Proteomic databases

PaxDbiQ5ISE2
PeptideAtlasiQ5ISE2
PRIDEiQ5ISE2

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
333473
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000071711; ENSMUSP00000071630; ENSMUSG00000059334
GeneIDi333473
KEGGimmu:333473
UCSCiuc009tfk.1 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
333473
MGIiMGI:3525151 Zfp36l3

Phylogenomic databases

eggNOGiKOG1677 Eukaryota
COG5063 LUCA
GeneTreeiENSGT00940000155076
HOGENOMiHOG000214117
InParanoidiQ5ISE2
OMAiITPRVAI
OrthoDBi1541140at2759
TreeFamiTF315463

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q5ISE2

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000059334 Expressed in 9 organ(s), highest expression level in placenta

Family and domain databases

InterProiView protein in InterPro
IPR011004 Trimer_LpxA-like_sf
IPR000571 Znf_CCCH
IPR036855 Znf_CCCH_sf
PfamiView protein in Pfam
PF00642 zf-CCCH, 2 hits
SMARTiView protein in SMART
SM00356 ZnF_C3H1, 2 hits
SUPFAMiSSF51161 SSF51161, 1 hit
SSF90229 SSF90229, 2 hits
PROSITEiView protein in PROSITE
PS50103 ZF_C3H1, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZ36L3_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5ISE2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 18, 2013
Last sequence update: February 15, 2005
Last modified: September 18, 2019
This is version 100 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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