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Protein
Submitted name:

Insulin-like growth factor binding protein-2

Gene

IGFBP-2

Organism
Equus caballus (Horse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Protein family/group databases

MEROPSiI31.953

Names & Taxonomyi

Protein namesi
Submitted name:
Insulin-like growth factor binding protein-2Imported
Gene namesi
Name:IGFBP-2Imported
OrganismiEquus caballus (Horse)Imported
Taxonomic identifieri9796 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaPerissodactylaEquidaeEquus

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

PRIDEiQ5IF07

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliQ5IF07
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini49 – 131Thyroglobulin type-1InterPro annotationAdd BLAST83

Phylogenomic databases

HOGENOMiHOG000253012

Family and domain databases

CDDicd00191 TY, 1 hit
Gene3Di4.10.800.10, 1 hit
InterProiView protein in InterPro
IPR012210 IGFBP-2
IPR009168 IGFBP1-6
IPR022321 IGFBP_1-6_chordata
IPR000716 Thyroglobulin_1
IPR036857 Thyroglobulin_1_sf
PANTHERiPTHR11551 PTHR11551, 1 hit
PfamiView protein in Pfam
PF00086 Thyroglobulin_1, 1 hit
PRINTSiPR01976 IGFBPFAMILY
PR01978 IGFBPFAMILY2
SMARTiView protein in SMART
SM00211 TY, 1 hit
SUPFAMiSSF57610 SSF57610, 1 hit
PROSITEiView protein in PROSITE
PS00484 THYROGLOBULIN_1_1, 1 hit
PS51162 THYROGLOBULIN_1_2, 1 hit

Sequencei

Sequence statusi: Fragment.

Q5IF07-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
GRKPLKSGMK ELAVYREKVS GQHRQMGRGG KHHHVVLEEP KKLRPPSART
60 70 80 90 100
PCQQELDQVL ERISTMRLPD ERGPLEHLYS LHIPNCDKHG LYNLKQCKMS
110 120 130 140
LNGQRGECWC VNPNTGKLIQ GAPTIRGDPE CHLFYNEQQG A
Length:141
Mass (Da):16,042
Last modified:February 15, 2005 - v1
Checksum:i86D5C5EE32AB584E
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei141Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY752931 mRNA Translation: AAW31639.1
UniGeneiEca.12715

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY752931 mRNA Translation: AAW31639.1
UniGeneiEca.12715

3D structure databases

ProteinModelPortaliQ5IF07
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

MEROPSiI31.953

Proteomic databases

PRIDEiQ5IF07

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOGENOMiHOG000253012

Family and domain databases

CDDicd00191 TY, 1 hit
Gene3Di4.10.800.10, 1 hit
InterProiView protein in InterPro
IPR012210 IGFBP-2
IPR009168 IGFBP1-6
IPR022321 IGFBP_1-6_chordata
IPR000716 Thyroglobulin_1
IPR036857 Thyroglobulin_1_sf
PANTHERiPTHR11551 PTHR11551, 1 hit
PfamiView protein in Pfam
PF00086 Thyroglobulin_1, 1 hit
PRINTSiPR01976 IGFBPFAMILY
PR01978 IGFBPFAMILY2
SMARTiView protein in SMART
SM00211 TY, 1 hit
SUPFAMiSSF57610 SSF57610, 1 hit
PROSITEiView protein in PROSITE
PS00484 THYROGLOBULIN_1_1, 1 hit
PS51162 THYROGLOBULIN_1_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ5IF07_HORSE
AccessioniPrimary (citable) accession number: Q5IF07
Entry historyiIntegrated into UniProtKB/TrEMBL: February 15, 2005
Last sequence update: February 15, 2005
Last modified: December 20, 2017
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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