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Protein
Submitted name:

Protein kinase C and casein kinase substrate in neurons 3

Gene

Pacsin3

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • cytoskeletal protein binding Source: GO_Central
  • kinase activity Source: UniProtKB-KW
  • phospholipid binding Source: GO_Central

GO - Biological processi

Keywordsi

Molecular functionKinaseImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
Protein kinase C and casein kinase substrate in neurons 3Imported
Submitted name:
Syndapin IIIImported
Gene namesi
Name:Pacsin3Imported
Synonyms:SdpIIIImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi1307327 Pacsin3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
CoblQ5NBX13EBI-7003023,EBI-1550138From Mus musculus.

GO - Molecular functioni

Protein-protein interaction databases

IntActiQ5I2Z0, 1 interactor
Q5I2Z0, 1 interactor

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 280F-BARInterPro annotationAdd BLAST271
Domaini363 – 424SH3InterPro annotationAdd BLAST62

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili185 – 216Sequence analysisAdd BLAST32

Keywords - Domaini

Coiled coilPROSITE-ProRule annotationSAAS annotation, SH3 domainPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG2856 Eukaryota
ENOG410XRX2 LUCA
HOGENOMiHOG000007245
HOVERGENiHBG053486
KOiK20123

Family and domain databases

Gene3Di1.20.1270.60, 1 hit
InterProiView protein in InterPro
IPR027267 AH/BAR_dom_sf
IPR031160 F_BAR
IPR001060 FCH_dom
IPR028523 PACSIN3
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
PANTHERiPTHR23065:SF18 PTHR23065:SF18, 1 hit
PfamiView protein in Pfam
PF00611 FCH, 1 hit
PF14604 SH3_9, 1 hit
PRINTSiPR00452 SH3DOMAIN
SMARTiView protein in SMART
SM00055 FCH, 1 hit
SM00326 SH3, 1 hit
SUPFAMiSSF103657 SSF103657, 1 hit
SSF50044 SSF50044, 1 hit
PROSITEiView protein in PROSITE
PS51741 F_BAR, 1 hit
PS50002 SH3, 1 hit

Sequencei

Sequence statusi: Complete.

Q5I2Z0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAPEEDAGGE VLVGSFWEAG NYRRTVQRVE DGHRLCGDLI SCFQERARIE
60 70 80 90 100
KAYAQQLADW ARKWRGAVEK GPQYGTLEKA WHAFFTAAER LSELHLEVRE
110 120 130 140 150
KLHGPDSERV RTWQRGAFHR PVLGGFRESR AAEDGFRKAQ KPWLKRLKEV
160 170 180 190 200
EASKKSYHTA RKDEKTAQTR ESHAKADSSM SQEQLRKLQE RVGRCTKEAE
210 220 230 240 250
KMKTQYEQTL AELNRYTPRY MEDMEQAFES CQAAERQRLL FFKDVLLTLH
260 270 280 290 300
QHLDLSSSDK FHELHRDLQR GIEDASDEED LRWWRSTHGP GMAMNWPQFE
310 320 330 340 350
EWSLDTQRAI SRKEKGGRSP DEVTLTSIVP TRDGTAPPPQ SPSSPGSGQD
360 370 380 390 400
EDWSDEESPR KAGTGVRVRA LYDYAGQEAD ELSFRAGEEL LKMSEEDEQG
410 420
WCQGQLQSGR IGLYPANYVE CVGA
Length:424
Mass (Da):48,641
Last modified:February 15, 2005 - v1
Checksum:iC393D375A6B87A58
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC100636 mRNA Translation: AAI00637.1
AY858802 mRNA Translation: AAW51118.1
RefSeqiNP_001009966.1, NM_001009966.2
UniGeneiRn.15416

Genome annotation databases

GeneIDi311187
KEGGirno:311187
UCSCiRGD:1307327 rat

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC100636 mRNA Translation: AAI00637.1
AY858802 mRNA Translation: AAW51118.1
RefSeqiNP_001009966.1, NM_001009966.2
UniGeneiRn.15416

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ5I2Z0, 1 interactor
Q5I2Z0, 1 interactor

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi311187
KEGGirno:311187
UCSCiRGD:1307327 rat

Organism-specific databases

CTDi29763
RGDi1307327 Pacsin3

Phylogenomic databases

eggNOGiKOG2856 Eukaryota
ENOG410XRX2 LUCA
HOGENOMiHOG000007245
HOVERGENiHBG053486
KOiK20123

Family and domain databases

Gene3Di1.20.1270.60, 1 hit
InterProiView protein in InterPro
IPR027267 AH/BAR_dom_sf
IPR031160 F_BAR
IPR001060 FCH_dom
IPR028523 PACSIN3
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
PANTHERiPTHR23065:SF18 PTHR23065:SF18, 1 hit
PfamiView protein in Pfam
PF00611 FCH, 1 hit
PF14604 SH3_9, 1 hit
PRINTSiPR00452 SH3DOMAIN
SMARTiView protein in SMART
SM00055 FCH, 1 hit
SM00326 SH3, 1 hit
SUPFAMiSSF103657 SSF103657, 1 hit
SSF50044 SSF50044, 1 hit
PROSITEiView protein in PROSITE
PS51741 F_BAR, 1 hit
PS50002 SH3, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ5I2Z0_RAT
AccessioniPrimary (citable) accession number: Q5I2Z0
Entry historyiIntegrated into UniProtKB/TrEMBL: February 15, 2005
Last sequence update: February 15, 2005
Last modified: November 7, 2018
This is version 114 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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