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Protein

Tetratricopeptide repeat protein 32

Gene

TTC32

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Tetratricopeptide repeat protein 32
Short name:
TPR repeat protein 32
Gene namesi
Name:TTC32
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000183891.5
HGNCiHGNC:32954 TTC32
neXtProtiNX_Q5I0X7

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000183891
PharmGKBiPA145147867

Polymorphism and mutation databases

BioMutaiTTC32
DMDMi74755518

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002631001 – 151Tetratricopeptide repeat protein 32Add BLAST151

Proteomic databases

MaxQBiQ5I0X7
PaxDbiQ5I0X7
PeptideAtlasiQ5I0X7
PRIDEiQ5I0X7
ProteomicsDBi62970

PTM databases

iPTMnetiQ5I0X7
PhosphoSitePlusiQ5I0X7

Expressioni

Gene expression databases

BgeeiENSG00000183891 Expressed in 191 organ(s), highest expression level in left lobe of thyroid gland
CleanExiHS_TTC32
ExpressionAtlasiQ5I0X7 baseline and differential
GenevisibleiQ5I0X7 HS

Organism-specific databases

HPAiHPA036024

Interactioni

Binary interactionsi

Protein-protein interaction databases

BioGridi126236, 10 interactors
IntActiQ5I0X7, 9 interactors
MINTiQ5I0X7
STRINGi9606.ENSP00000333018

Structurei

3D structure databases

ProteinModelPortaliQ5I0X7
SMRiQ5I0X7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati8 – 41TPR 1Add BLAST34
Repeati58 – 91TPR 2Add BLAST34
Repeati92 – 125TPR 3Add BLAST34

Keywords - Domaini

Repeat, TPR repeat

Phylogenomic databases

eggNOGiKOG1124 Eukaryota
COG0457 LUCA
GeneTreeiENSGT00390000011905
HOGENOMiHOG000068047
HOVERGENiHBG056063
InParanoidiQ5I0X7
OMAiIRQCACA
OrthoDBiEOG091G0S8L
PhylomeDBiQ5I0X7

Family and domain databases

Gene3Di1.25.40.10, 1 hit
InterProiView protein in InterPro
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
IPR001440 TPR_1
IPR019734 TPR_repeat
PfamiView protein in Pfam
PF00515 TPR_1, 1 hit
SMARTiView protein in SMART
SM00028 TPR, 2 hits
SUPFAMiSSF48452 SSF48452, 1 hit
PROSITEiView protein in PROSITE
PS50005 TPR, 2 hits
PS50293 TPR_REGION, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q5I0X7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEGQRQESHA TLTLAQAHFN NGEYAEAEAL YSAYIRRCAC AASSDESPGS
60 70 80 90 100
KCSPEDLATA YNNRGQIKYF RVDFYEAMDD YTSAIEVQPN FEVPYYNRGL
110 120 130 140 150
ILYRLGYFDD ALEDFKKVLD LNPGFQDATL SLKQTILDKE EKQRRNVAKN

Y
Length:151
Mass (Da):17,296
Last modified:February 15, 2005 - v1
Checksum:i81BE35CDA095B2D9
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
C9JV54C9JV54_HUMAN
Tetratricopeptide repeat protein 32
TTC32
86Annotation score:
B5MCJ1B5MCJ1_HUMAN
Tetratricopeptide repeat protein 32
TTC32
52Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC057850 mRNA Translation: AAH57850.1
CCDSiCCDS33151.1
RefSeqiNP_001008238.1, NM_001008237.2
UniGeneiHs.591547

Genome annotation databases

EnsembliENST00000333610; ENSP00000333018; ENSG00000183891
GeneIDi130502
KEGGihsa:130502
UCSCiuc002rdg.4 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC057850 mRNA Translation: AAH57850.1
CCDSiCCDS33151.1
RefSeqiNP_001008238.1, NM_001008237.2
UniGeneiHs.591547

3D structure databases

ProteinModelPortaliQ5I0X7
SMRiQ5I0X7
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi126236, 10 interactors
IntActiQ5I0X7, 9 interactors
MINTiQ5I0X7
STRINGi9606.ENSP00000333018

PTM databases

iPTMnetiQ5I0X7
PhosphoSitePlusiQ5I0X7

Polymorphism and mutation databases

BioMutaiTTC32
DMDMi74755518

Proteomic databases

MaxQBiQ5I0X7
PaxDbiQ5I0X7
PeptideAtlasiQ5I0X7
PRIDEiQ5I0X7
ProteomicsDBi62970

Protocols and materials databases

DNASUi130502
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000333610; ENSP00000333018; ENSG00000183891
GeneIDi130502
KEGGihsa:130502
UCSCiuc002rdg.4 human

Organism-specific databases

CTDi130502
EuPathDBiHostDB:ENSG00000183891.5
GeneCardsiTTC32
HGNCiHGNC:32954 TTC32
HPAiHPA036024
neXtProtiNX_Q5I0X7
OpenTargetsiENSG00000183891
PharmGKBiPA145147867
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1124 Eukaryota
COG0457 LUCA
GeneTreeiENSGT00390000011905
HOGENOMiHOG000068047
HOVERGENiHBG056063
InParanoidiQ5I0X7
OMAiIRQCACA
OrthoDBiEOG091G0S8L
PhylomeDBiQ5I0X7

Miscellaneous databases

GenomeRNAii130502
PROiPR:Q5I0X7

Gene expression databases

BgeeiENSG00000183891 Expressed in 191 organ(s), highest expression level in left lobe of thyroid gland
CleanExiHS_TTC32
ExpressionAtlasiQ5I0X7 baseline and differential
GenevisibleiQ5I0X7 HS

Family and domain databases

Gene3Di1.25.40.10, 1 hit
InterProiView protein in InterPro
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
IPR001440 TPR_1
IPR019734 TPR_repeat
PfamiView protein in Pfam
PF00515 TPR_1, 1 hit
SMARTiView protein in SMART
SM00028 TPR, 2 hits
SUPFAMiSSF48452 SSF48452, 1 hit
PROSITEiView protein in PROSITE
PS50005 TPR, 2 hits
PS50293 TPR_REGION, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiTTC32_HUMAN
AccessioniPrimary (citable) accession number: Q5I0X7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: February 15, 2005
Last modified: September 12, 2018
This is version 113 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
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