Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 114 (22 Apr 2020)
Sequence version 2 (20 May 2008)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Metaxin-3

Gene

MTX3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Could function in transport of proteins into the mitochondrion.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processProtein transport, Transport

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Metaxin-3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MTX3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:24812 MTX3

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q5HYI7

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion outer membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000177034

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134924631

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q5HYI7 Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
MTX3

Domain mapping of disease mutations (DMDM)

More...
DMDMi
189029218

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003371001 – 312Metaxin-3Add BLAST312

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei249PhosphoserineCombined sources1
Modified residuei284PhosphoserineCombined sources1
Modified residuei311PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q5HYI7

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q5HYI7

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q5HYI7

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q5HYI7

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q5HYI7

PeptideAtlas

More...
PeptideAtlasi
Q5HYI7

PRoteomics IDEntifications database

More...
PRIDEi
Q5HYI7

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
19149
62935 [Q5HYI7-1]
62936 [Q5HYI7-2]
62937 [Q5HYI7-4]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q5HYI7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q5HYI7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000177034 Expressed in deltoid and 201 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q5HYI7 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000177034 Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Part of a large protein complex spanning both mitochondrial membranes termed the mitochondrial intermembrane space bridging (MIB) complex.

1 Publication

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
131365, 33 interactors

Protein interaction database and analysis system

More...
IntActi
Q5HYI7, 28 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000423600

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q5HYI7 protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the metaxin family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3028 Eukaryota
ENOG41100SS LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000182919

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_044137_5_2_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q5HYI7

KEGG Orthology (KO)

More...
KOi
K17776

Identification of Orthologs from Complete Genome Data

More...
OMAi
WTWKTLT

Database of Orthologous Groups

More...
OrthoDBi
1472286at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q5HYI7

TreeFam database of animal gene trees

More...
TreeFami
TF313422

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036282 Glutathione-S-Trfase_C_sf
IPR040079 Glutathione_S-Trfase
IPR017410 Metaxin
IPR033468 Metaxin_GST
IPR019564 Sam37/metaxin_N

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF17171 GST_C_6, 1 hit
PF10568 Tom37, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF038150 Metaxin, 1 hit

Structure-Function Linkage Database

More...
SFLDi
SFLDS00019 Glutathione_Transferase_(cytos, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47616 SSF47616, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q5HYI7-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAAPLELSCW GGGWGLPSVH SESLVVMAYA KFSGAPLKVN VIDNTWRGSR
60 70 80 90 100
GDVPILTTED DMVSQPAKIL NFLRKQKYNA DYELSAKQGA DTLAYIALLE
110 120 130 140 150
EKLLPAVLHT FWVESDNYFT VTKPWFASQI PFPLSLILPG RMSKGALNRI
160 170 180 190 200
LLTRGQPPLY HLREVEAQIY RDAKECLNLL SNRLGTSQFF FGDTPSTLDA
210 220 230 240 250
YVFGFLAPLY KVRFPKVQLQ EHLKQLSNLC RFCDDILSSY FRLSLGGISP
260 270 280 290 300
AGQETVDANL QKLTQLVNKE SNLIEKMDDN LRQSPQLPPR KLPTLKLTPA
310
EEENNSFQRL SP
Length:312
Mass (Da):35,093
Last modified:May 20, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3B9BAB7CF64FF8EF
GO
Isoform 2 (identifier: Q5HYI7-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     144-158: KGALNRILLTRGQPP → QQILSSRAGTHMLRK
     159-312: Missing.

Show »
Length:158
Mass (Da):17,569
Checksum:iD1F883A663D02D5A
GO
Isoform 3 (identifier: Q5HYI7-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     247-248: GI → DG
     249-312: Missing.

Show »
Length:248
Mass (Da):27,901
Checksum:iBF7859179F6F9AF5
GO
Isoform 4 (identifier: Q5HYI7-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-61: Missing.

Show »
Length:251
Mass (Da):28,608
Checksum:iE3C9240EDD986AC0
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence CAD97995 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti50R → K in CAI46098 (PubMed:17974005).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_043600238S → R. Corresponds to variant dbSNP:rs9293796Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0468241 – 61Missing in isoform 4. 1 PublicationAdd BLAST61
Alternative sequenceiVSP_033893144 – 158KGALN…RGQPP → QQILSSRAGTHMLRK in isoform 2. 1 PublicationAdd BLAST15
Alternative sequenceiVSP_033894159 – 312Missing in isoform 2. 1 PublicationAdd BLAST154
Alternative sequenceiVSP_036207247 – 248GI → DG in isoform 3. 1 Publication2
Alternative sequenceiVSP_036208249 – 312Missing in isoform 3. 1 PublicationAdd BLAST64

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK296864 mRNA Translation: BAG59427.1
BX538064 mRNA Translation: CAD97995.1 Different initiation.
BX647596 mRNA Translation: CAI46098.1
AC112184 Genomic DNA No translation available.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS47239.2 [Q5HYI7-4]
CCDS54872.1 [Q5HYI7-5]
CCDS87308.1 [Q5HYI7-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001010891.4, NM_001010891.4 [Q5HYI7-4]
NP_001161213.1, NM_001167741.1 [Q5HYI7-5]
XP_005248552.1, XM_005248495.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000509852; ENSP00000423302; ENSG00000177034 [Q5HYI7-4]
ENST00000512528; ENSP00000424798; ENSG00000177034 [Q5HYI7-1]
ENST00000512560; ENSP00000423600; ENSG00000177034 [Q5HYI7-5]
ENST00000617335; ENSP00000484157; ENSG00000177034 [Q5HYI7-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
345778

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:345778

UCSC genome browser

More...
UCSCi
uc003kge.5 human [Q5HYI7-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK296864 mRNA Translation: BAG59427.1
BX538064 mRNA Translation: CAD97995.1 Different initiation.
BX647596 mRNA Translation: CAI46098.1
AC112184 Genomic DNA No translation available.
CCDSiCCDS47239.2 [Q5HYI7-4]
CCDS54872.1 [Q5HYI7-5]
CCDS87308.1 [Q5HYI7-1]
RefSeqiNP_001010891.4, NM_001010891.4 [Q5HYI7-4]
NP_001161213.1, NM_001167741.1 [Q5HYI7-5]
XP_005248552.1, XM_005248495.3

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi131365, 33 interactors
IntActiQ5HYI7, 28 interactors
STRINGi9606.ENSP00000423600

PTM databases

iPTMnetiQ5HYI7
PhosphoSitePlusiQ5HYI7

Polymorphism and mutation databases

BioMutaiMTX3
DMDMi189029218

Proteomic databases

EPDiQ5HYI7
jPOSTiQ5HYI7
MassIVEiQ5HYI7
MaxQBiQ5HYI7
PaxDbiQ5HYI7
PeptideAtlasiQ5HYI7
PRIDEiQ5HYI7
ProteomicsDBi19149
62935 [Q5HYI7-1]
62936 [Q5HYI7-2]
62937 [Q5HYI7-4]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
61562 37 antibodies

The DNASU plasmid repository

More...
DNASUi
345778

Genome annotation databases

EnsembliENST00000509852; ENSP00000423302; ENSG00000177034 [Q5HYI7-4]
ENST00000512528; ENSP00000424798; ENSG00000177034 [Q5HYI7-1]
ENST00000512560; ENSP00000423600; ENSG00000177034 [Q5HYI7-5]
ENST00000617335; ENSP00000484157; ENSG00000177034 [Q5HYI7-2]
GeneIDi345778
KEGGihsa:345778
UCSCiuc003kge.5 human [Q5HYI7-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
345778

GeneCards: human genes, protein and diseases

More...
GeneCardsi
MTX3
HGNCiHGNC:24812 MTX3
HPAiENSG00000177034 Low tissue specificity
neXtProtiNX_Q5HYI7
OpenTargetsiENSG00000177034
PharmGKBiPA134924631

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3028 Eukaryota
ENOG41100SS LUCA
GeneTreeiENSGT00950000182919
HOGENOMiCLU_044137_5_2_1
InParanoidiQ5HYI7
KOiK17776
OMAiWTWKTLT
OrthoDBi1472286at2759
PhylomeDBiQ5HYI7
TreeFamiTF313422

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
MTX3 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
345778
PharosiQ5HYI7 Tdark

Protein Ontology

More...
PROi
PR:Q5HYI7
RNActiQ5HYI7 protein

Gene expression databases

BgeeiENSG00000177034 Expressed in deltoid and 201 other tissues
GenevisibleiQ5HYI7 HS

Family and domain databases

InterProiView protein in InterPro
IPR036282 Glutathione-S-Trfase_C_sf
IPR040079 Glutathione_S-Trfase
IPR017410 Metaxin
IPR033468 Metaxin_GST
IPR019564 Sam37/metaxin_N
PfamiView protein in Pfam
PF17171 GST_C_6, 1 hit
PF10568 Tom37, 1 hit
PIRSFiPIRSF038150 Metaxin, 1 hit
SFLDiSFLDS00019 Glutathione_Transferase_(cytos, 1 hit
SUPFAMiSSF47616 SSF47616, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMTX3_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5HYI7
Secondary accession number(s): B4DL65
, E9PB57, Q7Z380, Q8NB92
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: May 20, 2008
Last modified: April 22, 2020
This is version 114 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. Human chromosome 5
    Human chromosome 5: entries, gene names and cross-references to MIM
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again