Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable malate:quinone oxidoreductase 1

Gene

mqo1

Organism
Staphylococcus epidermidis (strain ATCC 35984 / RP62A)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-malate + a quinone = oxaloacetate + reduced quinone.UniRule annotation

Cofactori

FADUniRule annotation

Pathwayi: tricarboxylic acid cycle

This protein is involved in step 1 of the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Probable malate:quinone oxidoreductase 2 (mqo2), Probable malate:quinone oxidoreductase 4 (mqo4), Probable malate:quinone oxidoreductase 3 (mqo3), Probable malate:quinone oxidoreductase 1 (mqo1)
This subpathway is part of the pathway tricarboxylic acid cycle, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route), the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processTricarboxylic acid cycle
LigandFAD, Flavoprotein

Enzyme and pathway databases

UniPathwayi
UPA00223;UER01008

Names & Taxonomyi

Protein namesi
Recommended name:
Probable malate:quinone oxidoreductase 1UniRule annotation (EC:1.1.5.4UniRule annotation)
Alternative name(s):
MQO 1UniRule annotation
Malate dehydrogenase [quinone] 1UniRule annotation
Gene namesi
Name:mqo1UniRule annotation
Ordered Locus Names:SERP1955
OrganismiStaphylococcus epidermidis (strain ATCC 35984 / RP62A)
Taxonomic identifieri176279 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000000531 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001287531 – 492Probable malate:quinone oxidoreductase 1Add BLAST492

Proteomic databases

PRIDEiQ5HLN0

Interactioni

Protein-protein interaction databases

STRINGi176279.SERP1955

Structurei

3D structure databases

ProteinModelPortaliQ5HLN0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MQO family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DWT Bacteria
COG0579 LUCA
HOGENOMiHOG000109379
KOiK00116
OMAiPHLDTRW

Family and domain databases

Gene3Di3.50.50.60, 1 hit
HAMAPiMF_00212 MQO, 1 hit
InterProiView protein in InterPro
IPR036188 FAD/NAD-bd_sf
IPR006231 MQO
PfamiView protein in Pfam
PF06039 Mqo, 1 hit
SUPFAMiSSF51905 SSF51905, 1 hit
TIGRFAMsiTIGR01320 mal_quin_oxido, 1 hit

Sequencei

Sequence statusi: Complete.

Q5HLN0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNTQHSKTDV ILIGGGIMSA TLGTLLKELT PEKDIQLFER LSQPGEESSN
60 70 80 90 100
VWNNAGTGHS ALCELNYTKE GKDGSVDITK AIHINEQFQI SKQFWAYLIR
110 120 130 140 150
EGHIESPDKF IQSVPHMSFV KGEENVKFLK SRVASLQKNV LFEKMKISQD
160 170 180 190 200
PEKINSWVPL MMEGRQSDEA IAITYDETGT DVNFGALTKK LIANLQQKNV
210 220 230 240 250
GINYKHEVLD IKKLNNGNWQ VVVKDLNTSN VMNYESKFVF IGAGGASLPL
260 270 280 290 300
LQKTKIKESK HIGGFPVSGL FLRCKNPDVI HRHHAKVYGK AEVGAPPMSV
310 320 330 340 350
PHLDTRFVNG EKSLLFGPFA GFSPKFLKNG SYLDLVKSVK PNNMITMLSA
360 370 380 390 400
GVKEFNLTKY LVSQLMLSNE ERINDLRVFL PEAKDEDWEV ITAGQRVQVI
410 420 430 440 450
KDTDKSKGQL QFGTEVITSE DGSLAALLGA SPGASTAVDI MFDVLQRCYK
460 470 480 490
SEFKSWEPKI KEMVPSFGLK LSEHEDMYHS INEEVKKYLN VK
Length:492
Mass (Da):55,032
Last modified:February 15, 2005 - v1
Checksum:iA0791686F3969AD3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000029 Genomic DNA Translation: AAW52837.1

Genome annotation databases

EnsemblBacteriaiAAW52837; AAW52837; SERP1955
KEGGiser:SERP1955

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000029 Genomic DNA Translation: AAW52837.1

3D structure databases

ProteinModelPortaliQ5HLN0
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi176279.SERP1955

Proteomic databases

PRIDEiQ5HLN0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAW52837; AAW52837; SERP1955
KEGGiser:SERP1955

Phylogenomic databases

eggNOGiENOG4105DWT Bacteria
COG0579 LUCA
HOGENOMiHOG000109379
KOiK00116
OMAiPHLDTRW

Enzyme and pathway databases

UniPathwayi
UPA00223;UER01008

Family and domain databases

Gene3Di3.50.50.60, 1 hit
HAMAPiMF_00212 MQO, 1 hit
InterProiView protein in InterPro
IPR036188 FAD/NAD-bd_sf
IPR006231 MQO
PfamiView protein in Pfam
PF06039 Mqo, 1 hit
SUPFAMiSSF51905 SSF51905, 1 hit
TIGRFAMsiTIGR01320 mal_quin_oxido, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiMQO1_STAEQ
AccessioniPrimary (citable) accession number: Q5HLN0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2005
Last sequence update: February 15, 2005
Last modified: November 7, 2018
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again