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UniProtKB - Q5HGK3 (FABD_STAAC)
Protein
Malonyl CoA-acyl carrier protein transacylase
Gene
fabD
Organism
Staphylococcus aureus (strain COL)
Status
Functioni
Catalytic activityi
- EC:2.3.1.39
: fatty acid biosynthesis Pathwayi
This protein is involved in the pathway fatty acid biosynthesis, which is part of Lipid metabolism.View all proteins of this organism that are known to be involved in the pathway fatty acid biosynthesis and in Lipid metabolism.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 89 | By similarity | 1 | |
Active sitei | 199 | By similarity | 1 |
GO - Molecular functioni
- [acyl-carrier-protein] S-malonyltransferase activity Source: UniProtKB-EC
GO - Biological processi
- fatty acid biosynthetic process Source: UniProtKB-UniPathway
Keywordsi
Molecular function | Acyltransferase, Transferase |
Biological process | Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism |
Enzyme and pathway databases
UniPathwayi | UPA00094 |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:fabD Ordered Locus Names:SACOL1244 |
Organismi | Staphylococcus aureus (strain COL) |
Taxonomic identifieri | 93062 [NCBI] |
Taxonomic lineagei | Bacteria › Firmicutes › Bacilli › Bacillales › Staphylococcaceae › Staphylococcus › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000194221 | 1 – 308 | Malonyl CoA-acyl carrier protein transacylaseAdd BLAST | 308 |
Family & Domainsi
Sequence similaritiesi
Belongs to the FabD family.Curated
Phylogenomic databases
HOGENOMi | CLU_030558_0_1_9 |
OMAi | AANYNCP |
Family and domain databases
Gene3Di | 3.40.366.10, 1 hit |
InterProi | View protein in InterPro IPR001227, Ac_transferase_dom_sf IPR014043, Acyl_transferase IPR016035, Acyl_Trfase/lysoPLipase IPR024925, Malonyl_CoA-ACP_transAc IPR004410, Malonyl_CoA-ACP_transAc_FabD IPR016036, Malonyl_transacylase_ACP-bd |
Pfami | View protein in Pfam PF00698, Acyl_transf_1, 1 hit |
PIRSFi | PIRSF000446, Mct, 1 hit |
SMARTi | View protein in SMART SM00827, PKS_AT, 1 hit |
SUPFAMi | SSF52151, SSF52151, 1 hit SSF55048, SSF55048, 1 hit |
TIGRFAMsi | TIGR00128, fabD, 1 hit |
i Sequence
Sequence statusi: Complete.
Q5HGK3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSKTAIIFPG QGAQKVGMAQ DLFNNNDQAT EILTSAANTL DFDILETMFT
60 70 80 90 100
DEEGKLGETE NTQPALLTHS SALLAALKNL NPDFTMGHSL GEYSSLVAAD
110 120 130 140 150
VLSFEDAVKI VRKRGQLMAQ AFPTGVGSMA AVLGLDFDKV DEICKSLSSD
160 170 180 190 200
DKIIEPANIN CPGQIVVSGH KALIDELVEK GKSLGAKRVM PLAVSGPFHS
210 220 230 240 250
SLMKVIEEDF SSYINQFEWR DAKFPVVQNV NAQGETDKEV IKSNMVKQLY
260 270 280 290 300
SPVQFINSTE WLIDQGVDHF IEIGPGKVLS GLIKKINRDV KLTSIQTLED
VKGWNEND
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP000046 Genomic DNA Translation: AAW38078.1 |
RefSeqi | WP_000047348.1, NC_002951.2 |
Genome annotation databases
EnsemblBacteriai | AAW38078; AAW38078; SACOL1244 |
KEGGi | sac:SACOL1244 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP000046 Genomic DNA Translation: AAW38078.1 |
RefSeqi | WP_000047348.1, NC_002951.2 |
3D structure databases
AlphaFoldDBi | Q5HGK3 |
SMRi | Q5HGK3 |
ModBasei | Search... |
Genome annotation databases
EnsemblBacteriai | AAW38078; AAW38078; SACOL1244 |
KEGGi | sac:SACOL1244 |
Phylogenomic databases
HOGENOMi | CLU_030558_0_1_9 |
OMAi | AANYNCP |
Enzyme and pathway databases
UniPathwayi | UPA00094 |
Family and domain databases
Gene3Di | 3.40.366.10, 1 hit |
InterProi | View protein in InterPro IPR001227, Ac_transferase_dom_sf IPR014043, Acyl_transferase IPR016035, Acyl_Trfase/lysoPLipase IPR024925, Malonyl_CoA-ACP_transAc IPR004410, Malonyl_CoA-ACP_transAc_FabD IPR016036, Malonyl_transacylase_ACP-bd |
Pfami | View protein in Pfam PF00698, Acyl_transf_1, 1 hit |
PIRSFi | PIRSF000446, Mct, 1 hit |
SMARTi | View protein in SMART SM00827, PKS_AT, 1 hit |
SUPFAMi | SSF52151, SSF52151, 1 hit SSF55048, SSF55048, 1 hit |
TIGRFAMsi | TIGR00128, fabD, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | FABD_STAAC | |
Accessioni | Q5HGK3Primary (citable) accession number: Q5HGK3 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 24, 2006 |
Last sequence update: | February 15, 2005 | |
Last modified: | May 25, 2022 | |
This is version 94 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Documents
- PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families