UniProtKB - Q5HFP9 (EX7S_STAAC)
Protein
Exodeoxyribonuclease 7 small subunit
Gene
xseB
Organism
Staphylococcus aureus (strain COL)
Status
Functioni
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.UniRule annotation
Catalytic activityi
- Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.UniRule annotation EC:3.1.11.6
GO - Molecular functioni
- exodeoxyribonuclease VII activity Source: UniProtKB-UniRule
GO - Biological processi
- DNA catabolic process Source: UniProtKB-UniRule
Keywordsi
Molecular function | Exonuclease, Hydrolase, Nuclease |
Enzyme and pathway databases
BioCyci | SAUR93062:G1G4B-1678-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Exodeoxyribonuclease 7 small subunitUniRule annotation (EC:3.1.11.6UniRule annotation)Alternative name(s): Exodeoxyribonuclease VII small subunitUniRule annotation Short name: Exonuclease VII small subunitUniRule annotation |
Gene namesi | Name:xseBUniRule annotation Ordered Locus Names:SACOL1567 |
Organismi | Staphylococcus aureus (strain COL) |
Taxonomic identifieri | 93062 [NCBI] |
Taxonomic lineagei | Bacteria › Firmicutes › Bacilli › Bacillales › Staphylococcaceae › Staphylococcus › |
Proteomesi |
|
Subcellular locationi
- Cytoplasm UniRule annotation
GO - Cellular componenti
- cytoplasm Source: UniProtKB-SubCell
- exodeoxyribonuclease VII complex Source: InterPro
Keywords - Cellular componenti
CytoplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000207003 | 1 – 76 | Exodeoxyribonuclease 7 small subunitAdd BLAST | 76 |
Interactioni
Subunit structurei
Heterooligomer composed of large and small subunits.
UniRule annotationFamily & Domainsi
Sequence similaritiesi
Belongs to the XseB family.UniRule annotation
Phylogenomic databases
HOGENOMi | CLU_145918_3_2_9 |
OMAi | PLNDYKG |
Family and domain databases
Gene3Di | 1.10.287.1040, 1 hit |
HAMAPi | MF_00337, Exonuc_7_S, 1 hit |
InterProi | View protein in InterPro IPR003761, Exonuc_VII_S IPR037004, Exonuc_VII_ssu_sf |
PANTHERi | PTHR34137, PTHR34137, 1 hit |
Pfami | View protein in Pfam PF02609, Exonuc_VII_S, 1 hit |
PIRSFi | PIRSF006488, Exonuc_VII_S, 1 hit |
SUPFAMi | SSF116842, SSF116842, 1 hit |
TIGRFAMsi | TIGR01280, xseB, 1 hit |
i Sequence
Sequence statusi: Complete.
Q5HFP9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTKETQSFEE MMQELEQIVQ KLDNETVSLE ESLDLYQRGM KLSAACDTTL
60 70
KNAEKKVNDL IKEEAEDVKN DESTDE
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP000046 Genomic DNA Translation: AAW36759.1 |
RefSeqi | WP_000159865.1, NC_002951.2 |
Genome annotation databases
EnsemblBacteriai | AAW36759; AAW36759; SACOL1567 |
GeneIDi | 45574747 |
KEGGi | sac:SACOL1567 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP000046 Genomic DNA Translation: AAW36759.1 |
RefSeqi | WP_000159865.1, NC_002951.2 |
3D structure databases
SMRi | Q5HFP9 |
ModBasei | Search... |
Genome annotation databases
EnsemblBacteriai | AAW36759; AAW36759; SACOL1567 |
GeneIDi | 45574747 |
KEGGi | sac:SACOL1567 |
Phylogenomic databases
HOGENOMi | CLU_145918_3_2_9 |
OMAi | PLNDYKG |
Enzyme and pathway databases
BioCyci | SAUR93062:G1G4B-1678-MONOMER |
Family and domain databases
Gene3Di | 1.10.287.1040, 1 hit |
HAMAPi | MF_00337, Exonuc_7_S, 1 hit |
InterProi | View protein in InterPro IPR003761, Exonuc_VII_S IPR037004, Exonuc_VII_ssu_sf |
PANTHERi | PTHR34137, PTHR34137, 1 hit |
Pfami | View protein in Pfam PF02609, Exonuc_VII_S, 1 hit |
PIRSFi | PIRSF006488, Exonuc_VII_S, 1 hit |
SUPFAMi | SSF116842, SSF116842, 1 hit |
TIGRFAMsi | TIGR01280, xseB, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | EX7S_STAAC | |
Accessioni | Q5HFP9Primary (citable) accession number: Q5HFP9 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | June 7, 2005 |
Last sequence update: | February 15, 2005 | |
Last modified: | December 2, 2020 | |
This is version 93 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |