Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Elongation factor Tu

Gene

tuf1

more
Organism
Ehrlichia ruminantium (strain Welgevonden)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

Caution

The equivalent of tuf1 in the CIRAD genome (PubMed:16547041, AC Q5FCW3) is annotated as a frameshift version requiring 2 frameshifts to produce full-length protein.Curated

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi15 – 22GTPUniRule annotation8
Nucleotide bindingi80 – 84GTPUniRule annotation5
Nucleotide bindingi135 – 138GTPUniRule annotation4

GO - Molecular functioni

Keywordsi

Molecular functionElongation factor
Biological processProtein biosynthesis
LigandGTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Short name:
EF-TuUniRule annotation
Gene namesi
Name:tuf1UniRule annotation
Synonyms:tufA
Ordered Locus Names:Erum1660
AND
Name:tuf2UniRule annotation
Synonyms:tufB
Ordered Locus Names:Erum6090, ERWE_CDS_06400
OrganismiEhrlichia ruminantium (strain Welgevonden)
Taxonomic identifieri254945 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesAnaplasmataceaeEhrlichia
Proteomesi
  • UP000001021 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003373771 – 395Elongation factor TuAdd BLAST395

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi254945.ERWE_CDS_06400

Structurei

3D structure databases

ProteinModelPortaliQ5HAS0
SMRiQ5HAS0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 205tr-type GAdd BLAST200

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni15 – 22G1By similarity8
Regioni59 – 63G2By similarity5
Regioni80 – 83G3By similarity4
Regioni135 – 138G4By similarity4
Regioni173 – 175G5By similarity3

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105CGV Bacteria
COG0050 LUCA
HOGENOMiHOG000229290
KOiK02358
OrthoDBiPOG091H00LA

Family and domain databases

CDDicd03697 EFTU_II, 1 hit
HAMAPiMF_00118_B EF_Tu_B, 1 hit
InterProiView protein in InterPro
IPR004161 EFTu-like_2
IPR033720 EFTU_2
IPR031157 G_TR_CS
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR000795 TF_GTP-bd_dom
IPR009000 Transl_B-barrel_sf
IPR009001 Transl_elong_EF1A/Init_IF2_C
IPR004541 Transl_elong_EFTu/EF1A_bac/org
IPR004160 Transl_elong_EFTu/EF1A_C
PfamiView protein in Pfam
PF00009 GTP_EFTU, 1 hit
PF03144 GTP_EFTU_D2, 1 hit
PF03143 GTP_EFTU_D3, 1 hit
PRINTSiPR00315 ELONGATNFCT
SUPFAMiSSF50447 SSF50447, 1 hit
SSF50465 SSF50465, 1 hit
SSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00485 EF-Tu, 1 hit
TIGR00231 small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS00301 G_TR_1, 1 hit
PS51722 G_TR_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q5HAS0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVDGRKPHIN VGTIGHVDHG KTTLTAALTT VLAKRLSGEG NKSVKYDEID
60 70 80 90 100
KAPEEKARGI TISTAHVEYE TENRHYAHVD CPGHADYIKN MITGAAQMDA
110 120 130 140 150
AILVVSATDG AMPQTREHIL LAKQVGVKDI VVWMNKCDVV DDEEMLSLVE
160 170 180 190 200
MEIRELLTKY GYPGDDIDVV KGSAVKALEE ESADGVWSEK IMELMNALEK
210 220 230 240 250
IDLPIREKDK PFLMSIEDVF SIPGRGTVVT GRIERGVIKV GDKIDIVGLR
260 270 280 290 300
DIQSTVCTGV EMFHKALDAG EAGDNAGILL RGIKKEDVER GQVLSAPGQI
310 320 330 340 350
HSYKGFKAEV YVLKKEEGGR HTPFFSNYQP QFYVRTTDVT GNIKLPDGVE
360 370 380 390
MVMPGDNISI EVNLDKPVAI DKGLRFAIRE GGRTIGSGII TEILE
Length:395
Mass (Da):43,282
Last modified:February 15, 2005 - v1
Checksum:iC2B3B98AD64B94F0
GO

Sequence cautioni

The sequence CAI27134 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR767821 Genomic DNA Translation: CAH57882.1
CR767821 Genomic DNA Translation: CAH58341.1
CR925678 Genomic DNA Translation: CAI27134.1 Different initiation.
RefSeqiWP_011154850.1, NC_006832.1

Genome annotation databases

EnsemblBacteriaiCAH57882; CAH57882; Erum1660
CAH58341; CAH58341; Erum6090
CAI27134; CAI27134; ERWE_CDS_06400
GeneIDi33058428
KEGGieru:Erum1660
eru:Erum6090
erw:ERWE_CDS_06400

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR767821 Genomic DNA Translation: CAH57882.1
CR767821 Genomic DNA Translation: CAH58341.1
CR925678 Genomic DNA Translation: CAI27134.1 Different initiation.
RefSeqiWP_011154850.1, NC_006832.1

3D structure databases

ProteinModelPortaliQ5HAS0
SMRiQ5HAS0
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi254945.ERWE_CDS_06400

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAH57882; CAH57882; Erum1660
CAH58341; CAH58341; Erum6090
CAI27134; CAI27134; ERWE_CDS_06400
GeneIDi33058428
KEGGieru:Erum1660
eru:Erum6090
erw:ERWE_CDS_06400

Phylogenomic databases

eggNOGiENOG4105CGV Bacteria
COG0050 LUCA
HOGENOMiHOG000229290
KOiK02358
OrthoDBiPOG091H00LA

Family and domain databases

CDDicd03697 EFTU_II, 1 hit
HAMAPiMF_00118_B EF_Tu_B, 1 hit
InterProiView protein in InterPro
IPR004161 EFTu-like_2
IPR033720 EFTU_2
IPR031157 G_TR_CS
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR000795 TF_GTP-bd_dom
IPR009000 Transl_B-barrel_sf
IPR009001 Transl_elong_EF1A/Init_IF2_C
IPR004541 Transl_elong_EFTu/EF1A_bac/org
IPR004160 Transl_elong_EFTu/EF1A_C
PfamiView protein in Pfam
PF00009 GTP_EFTU, 1 hit
PF03144 GTP_EFTU_D2, 1 hit
PF03143 GTP_EFTU_D3, 1 hit
PRINTSiPR00315 ELONGATNFCT
SUPFAMiSSF50447 SSF50447, 1 hit
SSF50465 SSF50465, 1 hit
SSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00485 EF-Tu, 1 hit
TIGR00231 small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS00301 G_TR_1, 1 hit
PS51722 G_TR_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiEFTU_EHRRW
AccessioniPrimary (citable) accession number: Q5HAS0
Secondary accession number(s): Q5FD56
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 15, 2005
Last modified: October 10, 2018
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again