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Entry version 128 (02 Jun 2021)
Sequence version 1 (15 Feb 2005)
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Protein

Transcription initiation factor TFIID subunit 7-like

Gene

TAF7L

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Probably functions as a spermatogenesis-specific component of the DNA-binding general transcription factor complex TFIID, a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. May play a role in spermatogenesis (By similarity).

By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDevelopmental protein
Biological processDifferentiation, Spermatogenesis, Transcription, Transcription regulation

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q5H9L4

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-167161, HIV Transcription Initiation
R-HSA-167162, RNA Polymerase II HIV Promoter Escape
R-HSA-167172, Transcription of the HIV genome
R-HSA-674695, RNA Polymerase II Pre-transcription Events
R-HSA-6804756, Regulation of TP53 Activity through Phosphorylation
R-HSA-73776, RNA Polymerase II Promoter Escape
R-HSA-73779, RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
R-HSA-75953, RNA Polymerase II Transcription Initiation
R-HSA-76042, RNA Polymerase II Transcription Initiation And Promoter Clearance

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Transcription initiation factor TFIID subunit 7-like
Alternative name(s):
Cancer/testis antigen 40
Short name:
CT40
RNA polymerase II TBP-associated factor subunit Q
TATA box-binding protein-associated factor 50 kDa
Transcription initiation factor TFIID 50 kDa subunit
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TAF7L
Synonyms:TAF2Q
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:11548, TAF7L

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
300314, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q5H9L4

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000102387.15

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
54457

Open Targets

More...
OpenTargetsi
ENSG00000102387

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA36323

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q5H9L4, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
TAF7L

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74762183

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003078611 – 462Transcription initiation factor TFIID subunit 7-likeAdd BLAST462

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q5H9L4

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q5H9L4

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q5H9L4

PeptideAtlas

More...
PeptideAtlasi
Q5H9L4

PRoteomics IDEntifications database

More...
PRIDEi
Q5H9L4

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
62896 [Q5H9L4-1]
62897 [Q5H9L4-2]
62898 [Q5H9L4-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q5H9L4

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q5H9L4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Testis-specific.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000102387, Expressed in right testis and 86 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q5H9L4, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q5H9L4, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000102387, Tissue enriched (testis)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

TFIID is composed of TATA binding protein (TBP) and a number of TBP-associated factors (TAFs). TAF7L may replace TAF7 in a spermatogenesis-specific form of TFIID.

Interacts with TBP; the interaction occurs in a sub-population of cells (pachytene and haploid round spermatids) and is developmentally regulated through differential intracellular localization of the two proteins.

Interacts with TAF1 (By similarity).

By similarity

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
119964, 24 interactors

Protein interaction database and analysis system

More...
IntActi
Q5H9L4, 22 interactors

Molecular INTeraction database

More...
MINTi
Q5H9L4

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000361998

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q5H9L4, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q5H9L4

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 97DisorderedSequence analysisAdd BLAST97
Regioni327 – 366DisorderedSequence analysisAdd BLAST40

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili342 – 462Sequence analysisAdd BLAST121

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi9 – 49Polar residuesSequence analysisAdd BLAST41
Compositional biasi58 – 77Polar residuesSequence analysisAdd BLAST20
Compositional biasi330 – 365Acidic residuesSequence analysisAdd BLAST36

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TAF7 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4011, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000161565

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_037860_0_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q5H9L4

Identification of Orthologs from Complete Genome Data

More...
OMAi
KQIHYME

Database of Orthologous Groups

More...
OrthoDBi
1348389at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q5H9L4

TreeFam database of animal gene trees

More...
TreeFami
TF313044

Family and domain databases

Conserved Domains Database

More...
CDDi
cd08047, TAF7, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR037817, TAF7
IPR006751, TAFII55_prot_cons_reg

The PANTHER Classification System

More...
PANTHERi
PTHR12228, PTHR12228, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF04658, TAFII55_N, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01370, TAFII55_N, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q5H9L4-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MECPEGQLPI SSENDSTPTV STSEVTSQQE PQILVDRGSE TTYESSADIA
60 70 80 90 100
GDEGTQIPAD EDTQTDADSS AQAAAQAPEN FQEGKDMSES QDEVPDEVEN
110 120 130 140 150
QFILRLPLEH ACTVRNLARS QSVKMKDKLK IDLLPDGRHA VVEVEDVPLA
160 170 180 190 200
AKLVDLPCVI ESLRTLDKKT FYKTADISQM LVCTADGDIH LSPEEPAAST
210 220 230 240 250
DPNIVRKKER GREEKCVWKH GITPPLKNVR KKRFRKTQKK VPDVKEMEKS
260 270 280 290 300
SFTEYIESPD VENEVKRLLR SDAEAVSTRW EVIAEDGTKE IESQGSIPGF
310 320 330 340 350
LISSGMSSHK QGHTSSEYDM LREMFSDSRS NNDDDEDEDD EDEDEDEDED
360 370 380 390 400
EDEDKEEEEE DCSEEYLERQ LQAEFIESGQ YRANEGTSSI VMEIQKQIEK
410 420 430 440 450
KEKKLHKIQN KAQRQKDLIM KVENLTLKNH FQSVLEQLEL QEKQKNEKLI
460
SLQEQLQRFL KK
Length:462
Mass (Da):52,588
Last modified:February 15, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i92BB59377D35A62F
GO
Isoform 2 (identifier: Q5H9L4-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-86: Missing.

Show »
Length:376
Mass (Da):43,570
Checksum:i4D5BDFC2013DFE63
GO
Isoform 3 (identifier: Q5H9L4-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-86: Missing.
     317-390: Missing.

Show »
Length:302
Mass (Da):34,726
Checksum:i03FDA44019BFAB5A
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_03669534L → P1 PublicationCorresponds to variant dbSNP:rs5951328Ensembl.1
Natural variantiVAR_03669661E → K1 PublicationCorresponds to variant dbSNP:rs147493489EnsemblClinVar.1
Natural variantiVAR_036697308S → G2 PublicationsCorresponds to variant dbSNP:rs35899692Ensembl.1
Natural variantiVAR_036698350 – 351Missing 3 Publications2
Natural variantiVAR_036699458R → H2 PublicationsCorresponds to variant dbSNP:rs41310729Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0288471 – 86Missing in isoform 2 and isoform 3. 2 PublicationsAdd BLAST86
Alternative sequenceiVSP_028848317 – 390Missing in isoform 3. 1 PublicationAdd BLAST74

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF285595 mRNA Translation: AAK31974.1
AK026810 mRNA Translation: BAB15560.1
Z68331 Genomic DNA No translation available.
AL109801 Genomic DNA No translation available.
CH471115 Genomic DNA Translation: EAX02847.1
CH471115 Genomic DNA Translation: EAX02848.1
BC043391 mRNA Translation: AAH43391.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS35347.1 [Q5H9L4-1]
CCDS55466.1 [Q5H9L4-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001161946.1, NM_001168474.1 [Q5H9L4-2]
NP_079161.3, NM_024885.3 [Q5H9L4-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000324762; ENSP00000320283; ENSG00000102387 [Q5H9L4-3]
ENST00000356784; ENSP00000349235; ENSG00000102387 [Q5H9L4-2]
ENST00000372907; ENSP00000361998; ENSG00000102387 [Q5H9L4-1]

Database of genes from NCBI RefSeq genomes

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GeneIDi
54457

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:54457

UCSC genome browser

More...
UCSCi
uc004eha.4, human [Q5H9L4-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF285595 mRNA Translation: AAK31974.1
AK026810 mRNA Translation: BAB15560.1
Z68331 Genomic DNA No translation available.
AL109801 Genomic DNA No translation available.
CH471115 Genomic DNA Translation: EAX02847.1
CH471115 Genomic DNA Translation: EAX02848.1
BC043391 mRNA Translation: AAH43391.1
CCDSiCCDS35347.1 [Q5H9L4-1]
CCDS55466.1 [Q5H9L4-2]
RefSeqiNP_001161946.1, NM_001168474.1 [Q5H9L4-2]
NP_079161.3, NM_024885.3 [Q5H9L4-1]

3D structure databases

SMRiQ5H9L4
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi119964, 24 interactors
IntActiQ5H9L4, 22 interactors
MINTiQ5H9L4
STRINGi9606.ENSP00000361998

PTM databases

iPTMnetiQ5H9L4
PhosphoSitePlusiQ5H9L4

Genetic variation databases

BioMutaiTAF7L
DMDMi74762183

Proteomic databases

MassIVEiQ5H9L4
MaxQBiQ5H9L4
PaxDbiQ5H9L4
PeptideAtlasiQ5H9L4
PRIDEiQ5H9L4
ProteomicsDBi62896 [Q5H9L4-1]
62897 [Q5H9L4-2]
62898 [Q5H9L4-3]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
451, 119 antibodies

The DNASU plasmid repository

More...
DNASUi
54457

Genome annotation databases

EnsembliENST00000324762; ENSP00000320283; ENSG00000102387 [Q5H9L4-3]
ENST00000356784; ENSP00000349235; ENSG00000102387 [Q5H9L4-2]
ENST00000372907; ENSP00000361998; ENSG00000102387 [Q5H9L4-1]
GeneIDi54457
KEGGihsa:54457
UCSCiuc004eha.4, human [Q5H9L4-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
54457
DisGeNETi54457

GeneCards: human genes, protein and diseases

More...
GeneCardsi
TAF7L
HGNCiHGNC:11548, TAF7L
HPAiENSG00000102387, Tissue enriched (testis)
MIMi300314, gene
neXtProtiNX_Q5H9L4
OpenTargetsiENSG00000102387
PharmGKBiPA36323
VEuPathDBiHostDB:ENSG00000102387.15

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG4011, Eukaryota
GeneTreeiENSGT00940000161565
HOGENOMiCLU_037860_0_1_1
InParanoidiQ5H9L4
OMAiKQIHYME
OrthoDBi1348389at2759
PhylomeDBiQ5H9L4
TreeFamiTF313044

Enzyme and pathway databases

PathwayCommonsiQ5H9L4
ReactomeiR-HSA-167161, HIV Transcription Initiation
R-HSA-167162, RNA Polymerase II HIV Promoter Escape
R-HSA-167172, Transcription of the HIV genome
R-HSA-674695, RNA Polymerase II Pre-transcription Events
R-HSA-6804756, Regulation of TP53 Activity through Phosphorylation
R-HSA-73776, RNA Polymerase II Promoter Escape
R-HSA-73779, RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
R-HSA-75953, RNA Polymerase II Transcription Initiation
R-HSA-76042, RNA Polymerase II Transcription Initiation And Promoter Clearance

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
54457, 7 hits in 620 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
TAF7L, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
54457
PharosiQ5H9L4, Tbio

Protein Ontology

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PROi
PR:Q5H9L4
RNActiQ5H9L4, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
Search...

Gene expression databases

BgeeiENSG00000102387, Expressed in right testis and 86 other tissues
ExpressionAtlasiQ5H9L4, baseline and differential
GenevisibleiQ5H9L4, HS

Family and domain databases

CDDicd08047, TAF7, 1 hit
InterProiView protein in InterPro
IPR037817, TAF7
IPR006751, TAFII55_prot_cons_reg
PANTHERiPTHR12228, PTHR12228, 1 hit
PfamiView protein in Pfam
PF04658, TAFII55_N, 1 hit
SMARTiView protein in SMART
SM01370, TAFII55_N, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTAF7L_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5H9L4
Secondary accession number(s): Q5H9L6
, Q86XI4, Q9BXU5, Q9H5R0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: February 15, 2005
Last modified: June 2, 2021
This is version 128 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families
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