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UniProtKB - Q5H9I0 (TFDP3_HUMAN)

Entry version 140 (07 Apr 2021)
Sequence version 1 (15 Feb 2005)
Previous versions | rss
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Protein

Transcription factor Dp family member 3

Gene

TFDP3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Competitive inhibitor of E2F-mediated transactivation activity. Impairs E2F-mediated cell-cycle progression from G1 to S phase.3 Publications

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections ('Function', 'PTM / Processing', 'Pathology and Biotech') according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei121Critical for repression of E2F activity1
Sitei130Critical for repression of E2F activity1
Sitei131Critical for repression of E2F activity1
Sitei140Critical for repression of E2F activity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position and type of each DNA-binding domain present within the protein.<p><a href='/help/dna_bind' target='_top'>More...</a></p>DNA bindingi108 – 190Sequence analysisAdd BLAST83

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q5H9I0

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Transcription factor Dp family member 3
Alternative name(s):
Cancer/testis antigen 30
Short name:
CT30
Hepatocellular carcinoma-associated antigen 661
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TFDP3
Synonyms:DP4, HCA661
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:24603, TFDP3

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		300772, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q5H9I0

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000183434.9

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi112C → R: No effect on down-regulation of E2F transcriptional activity; when associated with or without R-161 or with V-164. 1
Mutagenesisi121T → K: Restores enhanced E2F-mediated transcriptional activity; when associated with Y-130; N-131 and E-145. 1 Publication1
Mutagenesisi130C → Y: Restores enhanced E2F-mediated transcriptional activity; when associated with K-121; N-131 and E-145. 1 Publication1
Mutagenesisi131Q → N: Restores enhanced E2F-mediated transcriptional activity; when associated with K-121; Y-130 and E-145. 1 Publication1
Mutagenesisi140K → E: Restores enhanced E2F-mediated transcriptional activity; when associated with K-121; Y-130 and N-131. 1 Publication1
Mutagenesisi161K → R: No effect on down-regulation of E2F transcriptional activity; when associated with or without R-112. 1
Mutagenesisi164T → V: No effect on down-regulation of E2F transcriptional activity; when associated R-112. 1

Organism-specific databases

DisGeNET

More...DisGeNETi		51270

Open Targets

More...OpenTargetsi		ENSG00000183434

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA134898258

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q5H9I0, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		TFDP3

Domain mapping of disease mutations (DMDM)

More...DMDMi		74762180

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003059401 – 405Transcription factor Dp family member 3Add BLAST405

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q5H9I0

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q5H9I0

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q5H9I0

PeptideAtlas

More...PeptideAtlasi		Q5H9I0

PRoteomics IDEntifications database

More...PRIDEi		Q5H9I0

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		62889

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q5H9I0

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q5H9I0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Predominantly expressed in testis. Low level of expression in pancreas. Highly expressed in ovarian and colon cancer cell lines.2 Publications

<p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

In response to DNA damage.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000183434, Expressed in buccal mucosa cell and 14 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q5H9I0, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000183434, Tissue enriched (testis)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Heterodimer: with E2F family members. TFDP3/E2F heterodimers do not bind DNA and repress E2F-dependent transcriptional activity.

2 Publications

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		119423, 30 interactors

Protein interaction database and analysis system

More...IntActi		Q5H9I0, 25 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000385461

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q5H9I0, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q5H9I0

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni175 – 306Involved in negatively regulating E2F activityAdd BLAST132
Regioni209 – 241DCB1By similarityAdd BLAST33
Regioni254 – 310DCB2By similarityAdd BLAST57

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi156 – 190DEF boxBy similarityAdd BLAST35

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi386 – 402Asp/Glu-rich (acidic; NCB domain)Add BLAST17

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The potential DNA-binding domain differs in sequence from that of other DP family members and cannot bind DNA.

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the E2F/DP family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG2829, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000167066

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_039874_3_1_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q5H9I0

Identification of Orthologs from Complete Genome Data

More...OMAi		NIKRRTY

Database of Orthologous Groups

More...OrthoDBi		1046304at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q5H9I0

TreeFam database of animal gene trees

More...TreeFami		TF314396

Family and domain databases

Conserved Domains Database

More...CDDi		cd14458, DP_DD, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.10.10.10, 1 hit
1.20.140.80, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR037241, E2F-DP_heterodim
IPR003316, E2F_WHTH_DNA-bd_dom
IPR038168, TF_DP_C_sf
IPR028315, TFDP3
IPR014889, Transc_factor_DP_C
IPR015648, Transcrpt_fac_DP
IPR036388, WH-like_DNA-bd_sf
IPR036390, WH_DNA-bd_sf

The PANTHER Classification System

More...PANTHERi		PTHR12548, PTHR12548, 1 hit
PTHR12548:SF13, PTHR12548:SF13, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF08781, DP, 1 hit
PF02319, E2F_TDP, 1 hit

PIRSF; a whole-protein classification database

More...PIRSFi		PIRSF009404, Transcription_factor_DP, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM01138, DP, 1 hit
SM01372, E2F_TDP, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF144074, SSF144074, 1 hit
SSF46785, SSF46785, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q5H9I0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAKYVSLTEA NEELKVLMDE NQTSRPVAVH TSTVNPLGKQ LLPKTFGQSS 
        60         70         80         90        100
VNIDQQVVIG MPQRPAASNI PVVGSPNPPS THFASQNQHS YSSPPWAGQH 
       110        120        130        140        150
NRKGEKNGMG LCRLSMKVWE TVQRKGTTSC QEVVGELVAK FRAASNHASP 
       160        170        180        190        200
NESAYDVKNI KRRTYDALNV LMAMNIISRE KKKIKWIGLT TNSAQNCQNL 
       210        220        230        240        250
RVERQKRLER IKQKQSELQQ LILQQIAFKN LVLRNQYVEE QVSQRPLPNS 
       260        270        280        290        300
VIHVPFIIIS SSKKTVINCS ISDDKSEYLF KFNSSFEIHD DTEVLMWMGM 
       310        320        330        340        350
TFGLESGSCS AEDLKMARNL VPKALEPYVT EMAQGTFGGV FTTAGSRSNG 
       360        370        380        390        400
TWLSASDLTN IAIGMLATSS GGSQYSGSRV ETPAVEEEEE EDNNDDDLSE 

NDEDD
Length:405
Mass (Da):44,967
Last modified:February 15, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iAE6F5709FE7E4C03
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAF37562 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF219119 mRNA Translation: AAF37562.2 Different initiation.
Z77249 Genomic DNA No translation available.
CH471107 Genomic DNA Translation: EAX11773.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS14636.2

NCBI Reference Sequences

More...RefSeqi		NP_057605.3, NM_016521.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000310125; ENSP00000385461; ENSG00000183434

Database of genes from NCBI RefSeq genomes

More...GeneIDi		51270

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:51270

UCSC genome browser

More...UCSCi		uc004exb.1, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF219119 mRNA Translation: AAF37562.2 Different initiation.
Z77249 Genomic DNA No translation available.
CH471107 Genomic DNA Translation: EAX11773.1
CCDSiCCDS14636.2
RefSeqiNP_057605.3, NM_016521.2

3D structure databases

SMRiQ5H9I0
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi119423, 30 interactors
IntActiQ5H9I0, 25 interactors
STRINGi9606.ENSP00000385461

PTM databases

iPTMnetiQ5H9I0
PhosphoSitePlusiQ5H9I0

Genetic variation databases

BioMutaiTFDP3
DMDMi74762180

Proteomic databases

jPOSTiQ5H9I0
MassIVEiQ5H9I0
PaxDbiQ5H9I0
PeptideAtlasiQ5H9I0
PRIDEiQ5H9I0
ProteomicsDBi62889

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		30265, 176 antibodies

The DNASU plasmid repository

More...DNASUi		51270

Genome annotation databases

EnsembliENST00000310125; ENSP00000385461; ENSG00000183434
GeneIDi51270
KEGGihsa:51270
UCSCiuc004exb.1, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		51270
DisGeNETi51270

GeneCards: human genes, protein and diseases

More...GeneCardsi		TFDP3
HGNCiHGNC:24603, TFDP3
HPAiENSG00000183434, Tissue enriched (testis)
MIMi300772, gene
neXtProtiNX_Q5H9I0
OpenTargetsiENSG00000183434
PharmGKBiPA134898258
VEuPathDBiHostDB:ENSG00000183434.9

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG2829, Eukaryota
GeneTreeiENSGT00940000167066
HOGENOMiCLU_039874_3_1_1
InParanoidiQ5H9I0
OMAiNIKRRTY
OrthoDBi1046304at2759
PhylomeDBiQ5H9I0
TreeFamiTF314396

Enzyme and pathway databases

PathwayCommonsiQ5H9I0

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		51270, 0 hits in 639 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		51270
PharosiQ5H9I0, Tbio

Protein Ontology

More...PROi		PR:Q5H9I0
RNActiQ5H9I0, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000183434, Expressed in buccal mucosa cell and 14 other tissues
GenevisibleiQ5H9I0, HS

Family and domain databases

CDDicd14458, DP_DD, 1 hit
Gene3Di1.10.10.10, 1 hit
1.20.140.80, 1 hit
InterProiView protein in InterPro
IPR037241, E2F-DP_heterodim
IPR003316, E2F_WHTH_DNA-bd_dom
IPR038168, TF_DP_C_sf
IPR028315, TFDP3
IPR014889, Transc_factor_DP_C
IPR015648, Transcrpt_fac_DP
IPR036388, WH-like_DNA-bd_sf
IPR036390, WH_DNA-bd_sf
PANTHERiPTHR12548, PTHR12548, 1 hit
PTHR12548:SF13, PTHR12548:SF13, 1 hit
PfamiView protein in Pfam
PF08781, DP, 1 hit
PF02319, E2F_TDP, 1 hit
PIRSFiPIRSF009404, Transcription_factor_DP, 1 hit
SMARTiView protein in SMART
SM01138, DP, 1 hit
SM01372, E2F_TDP, 1 hit
SUPFAMiSSF144074, SSF144074, 1 hit
SSF46785, SSF46785, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTFDP3_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5H9I0
Secondary accession number(s): Q6DK49, Q9NZ54
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 2, 2007
Last sequence update: February 15, 2005
Last modified: April 7, 2021
This is version 140 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families
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