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UniProtKB - Q5H8V1 (Q5H8V1_HUMAN)
Protein
Submitted name:
BAFF receptor
Gene
TNFRSF13C
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- signaling receptor activity Source: InterPro
GO - Biological processi
- tumor necrosis factor-mediated signaling pathway Source: InterPro
Keywordsi
Molecular function | ReceptorImported |
Names & Taxonomyi
Protein namesi | Submitted name: BAFF receptorImportedSubmitted name: BAFF-RImportedSubmitted name: Tumor necrosis factor receptor superfamily, member 13CImported |
Gene namesi | Name:TNFRSF13CImported Synonyms:BAFF-RImported ORF Names:hCG_41562Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Organism-specific databases
VEuPathDBi | HostDB:ENSG00000159958 |
Subcellular locationi
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 77 – 99 | HelicalSequence analysisAdd BLAST | 23 |
Keywords - Cellular componenti
MembraneExpressioni
Gene expression databases
Bgeei | ENSG00000159958, Expressed in tonsil and 163 other tissues |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 16 – 45 | BaffR-Tall_bindInterPro annotationAdd BLAST | 30 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 43 – 62 | DisorderedSequence analysisAdd BLAST | 20 | |
Regioni | 107 – 184 | DisorderedSequence analysisAdd BLAST | 78 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 108 – 127 | Basic and acidic residuesSequence analysisAdd BLAST | 20 | |
Compositional biasi | 141 – 159 | Pro residuesSequence analysisAdd BLAST | 19 | |
Compositional biasi | 169 – 184 | Polar residuesSequence analysisAdd BLAST | 16 |
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisPhylogenomic databases
HOGENOMi | CLU_131020_0_0_1 |
OMAi | AQCFDPL |
OrthoDBi | 1581486at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR022338, TNFR_13C IPR043521, TNFR_13C/17 IPR015336, TNFR_13C_TALL-1-bd |
PANTHERi | PTHR20437, PTHR20437, 1 hit PTHR20437:SF2, PTHR20437:SF2, 1 hit |
Pfami | View protein in Pfam PF09256, BaffR-Tall_bind, 1 hit |
PRINTSi | PR01964, TNFACTORR13C |
i Sequence
Sequence statusi: Complete.
Q5H8V1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MRRGPRSLRG RDAPAPTPCV PAECFDLLVR HCVACGLLRT PRPKPAGASS
60 70 80 90 100
PAPRTALQPQ ESVGAGAGEA ALPLPGLLFG APALLGLALV LALVLVGLVS
110 120 130 140 150
WRRRQRRLRG ASSAEAPDGD KDAPEPLDKV IILSPGISDA TAPAWPPPGE
160 170 180
DPGTTPPGHS VPVPATELGS TELVTTKTAG PEQQ
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC105123 mRNA Translation: AAI05124.1 BC112030 mRNA Translation: AAI12031.1 EF064710 Genomic DNA Translation: ABK41893.1 AB222990 Genomic DNA Translation: BAE16554.1 CH471095 Genomic DNA Translation: EAW60473.1 |
RefSeqi | NP_443177.1, NM_052945.3 |
Genome annotation databases
GeneIDi | 115650 |
KEGGi | hsa:115650 |
MANE-Selecti | ENST00000291232.5; ENSP00000291232.3; NM_052945.4; NP_443177.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC105123 mRNA Translation: AAI05124.1 BC112030 mRNA Translation: AAI12031.1 EF064710 Genomic DNA Translation: ABK41893.1 AB222990 Genomic DNA Translation: BAE16554.1 CH471095 Genomic DNA Translation: EAW60473.1 |
RefSeqi | NP_443177.1, NM_052945.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protocols and materials databases
Antibodypediai | 307, 703 antibodies from 40 providers |
DNASUi | 115650 |
Genome annotation databases
GeneIDi | 115650 |
KEGGi | hsa:115650 |
MANE-Selecti | ENST00000291232.5; ENSP00000291232.3; NM_052945.4; NP_443177.1 |
Organism-specific databases
CTDi | 115650 |
PharmGKBi | PA38466 |
VEuPathDBi | HostDB:ENSG00000159958 |
Phylogenomic databases
HOGENOMi | CLU_131020_0_0_1 |
OMAi | AQCFDPL |
OrthoDBi | 1581486at2759 |
Miscellaneous databases
BioGRID-ORCSi | 115650, 42 hits in 1034 CRISPR screens |
ChiTaRSi | TNFRSF13C, human |
GenomeRNAii | 115650 |
Gene expression databases
Bgeei | ENSG00000159958, Expressed in tonsil and 163 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR022338, TNFR_13C IPR043521, TNFR_13C/17 IPR015336, TNFR_13C_TALL-1-bd |
PANTHERi | PTHR20437, PTHR20437, 1 hit PTHR20437:SF2, PTHR20437:SF2, 1 hit |
Pfami | View protein in Pfam PF09256, BaffR-Tall_bind, 1 hit |
PRINTSi | PR01964, TNFACTORR13C |
MobiDBi | Search... |
Entry informationi
Entry namei | Q5H8V1_HUMAN | |
Accessioni | Q5H8V1Primary (citable) accession number: Q5H8V1 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 10, 2005 |
Last sequence update: | May 10, 2005 | |
Last modified: | January 19, 2022 | |
This is version 131 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |