UniProtKB - Q5H8A4 (PIGG_HUMAN)
GPI ethanolamine phosphate transferase 2
PIGG
Functioni
Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI second mannose.
1 Publication: glycosylphosphatidylinositol-anchor biosynthesis Pathwayi
This protein is involved in the pathway glycosylphosphatidylinositol-anchor biosynthesis, which is part of Glycolipid biosynthesis.View all proteins of this organism that are known to be involved in the pathway glycosylphosphatidylinositol-anchor biosynthesis and in Glycolipid biosynthesis.
GO - Molecular functioni
- CP2 mannose-ethanolamine phosphotransferase activity Source: MGI
- phosphotransferase activity, for other substituted phosphate groups Source: Reactome
GO - Biological processi
- GPI anchor biosynthetic process Source: MGI
- preassembly of GPI anchor in ER membrane Source: Reactome
Keywordsi
Molecular function | Transferase |
Biological process | GPI-anchor biosynthesis |
Enzyme and pathway databases
PathwayCommonsi | Q5H8A4 |
Reactomei | R-HSA-162710, Synthesis of glycosylphosphatidylinositol (GPI) |
SignaLinki | Q5H8A4 |
SIGNORi | Q5H8A4 |
UniPathwayi | UPA00196 |
Names & Taxonomyi
Protein namesi | Recommended name: GPI ethanolamine phosphate transferase 2 (EC:2.-.-.-)Alternative name(s): GPI7 homolog Short name: hGPI7 Phosphatidylinositol-glycan biosynthesis class G protein Short name: PIG-G |
Gene namesi | Name:PIGG Synonyms:GPI7 ORF Names:UNQ1930/PRO4405 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:25985, PIGG |
MIMi | 616918, gene |
neXtProti | NX_Q5H8A4 |
VEuPathDBi | HostDB:ENSG00000174227 |
Subcellular locationi
Endoplasmic reticulum
- Endoplasmic reticulum membrane 1 Publication; Multi-pass membrane protein 1 Publication
Endoplasmic reticulum
- endoplasmic reticulum Source: MGI
- endoplasmic reticulum membrane Source: Reactome
- integral component of endoplasmic reticulum membrane Source: GO_Central
Other locations
- membrane Source: UniProtKB
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 431 | LumenalSequence analysisAdd BLAST | 431 | |
Transmembranei | 432 – 452 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 471 – 491 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 506 – 526 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 552 – 572 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 699 – 719 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 721 – 741 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 752 – 772 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 789 – 809 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 812 – 832 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 879 – 899 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 919 – 939 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 955 – 975 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
Endoplasmic reticulum, MembranePathology & Biotechi
Involvement in diseasei
Intellectual developmental disorder, autosomal recessive 53 (MRT53)
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_076775 | 669 | R → C in MRT53; almost complete loss of ethanolamine phosphate transferase activity, as evidenced by abnormal accumulation of the GPI precursors H7 and H7' and absence of mature GPI precursor H8 in patient lymphocytes; does not affect protein expression levels in transfected HEK293 cells. 1 PublicationCorresponds to variant dbSNP:rs372392424EnsemblClinVar. | 1 |
Keywords - Diseasei
Disease variant, Mental retardationOrganism-specific databases
DisGeNETi | 54872 |
MalaCardsi | PIGG |
MIMi | 616917, phenotype |
OpenTargetsi | ENSG00000174227 |
Orphaneti | 488635, Early-onset epilepsy-intellectual disability-brain anomalies syndrome 280, Wolf-Hirschhorn syndrome |
PharmGKBi | PA143485575 |
Miscellaneous databases
Pharosi | Q5H8A4, Tbio |
Genetic variation databases
BioMutai | PIGG |
DMDMi | 74707851 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000246185 | 1 – 983 | GPI ethanolamine phosphate transferase 2Add BLAST | 983 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Glycosylationi | 194 | N-linked (GlcNAc...) asparagineSequence analysis | 1 |
Keywords - PTMi
GlycoproteinProteomic databases
EPDi | Q5H8A4 |
jPOSTi | Q5H8A4 |
MassIVEi | Q5H8A4 |
MaxQBi | Q5H8A4 |
PaxDbi | Q5H8A4 |
PeptideAtlasi | Q5H8A4 |
PRIDEi | Q5H8A4 |
ProteomicsDBi | 4448 62844 [Q5H8A4-1] 62845 [Q5H8A4-2] 62846 [Q5H8A4-3] 62847 [Q5H8A4-4] 62848 [Q5H8A4-5] |
PTM databases
GlyGeni | Q5H8A4, 1 site |
iPTMneti | Q5H8A4 |
PhosphoSitePlusi | Q5H8A4 |
Expressioni
Gene expression databases
Bgeei | ENSG00000174227, Expressed in lower esophagus muscularis layer and 225 other tissues |
ExpressionAtlasi | Q5H8A4, baseline and differential |
Genevisiblei | Q5H8A4, HS |
Organism-specific databases
HPAi | ENSG00000174227, Low tissue specificity |
Interactioni
Subunit structurei
Forms a complex with PIGF. PIGF is required to stabilize it. Competes with PIGO for the binding of PIGF.
Protein-protein interaction databases
BioGRIDi | 120220, 109 interactors |
IntActi | Q5H8A4, 11 interactors |
MINTi | Q5H8A4 |
STRINGi | 9606.ENSP00000415203 |
Miscellaneous databases
RNActi | Q5H8A4, protein |
Family & Domainsi
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG2125, Eukaryota |
GeneTreei | ENSGT00910000144269 |
HOGENOMi | CLU_055386_0_0_1 |
InParanoidi | Q5H8A4 |
OMAi | RVKFGHD |
OrthoDBi | 848878at2759 |
PhylomeDBi | Q5H8A4 |
TreeFami | TF300609 |
Family and domain databases
CDDi | cd16024, GPI_EPT_2, 1 hit |
Gene3Di | 3.40.720.10, 1 hit |
InterProi | View protein in InterPro IPR017850, Alkaline_phosphatase_core_sf IPR002591, Phosphodiest/P_Trfase IPR037674, PIG-G_N IPR039527, PIGG/GPI7 IPR045687, PIGG/GPI7_C |
PANTHERi | PTHR23072, PTHR23072, 1 hit |
Pfami | View protein in Pfam PF01663, Phosphodiest, 1 hit PF19316, PIGO_PIGG, 1 hit |
SUPFAMi | SSF53649, SSF53649, 1 hit |
s (6+)i Sequence
Sequence statusi: Complete.
This entry describes 6 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 6 described isoforms and 6 potential isoforms that are computationally mapped.Show allAlign All
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MRLGSGTFAT CCVAIEVLGI AVFLRGFFPA PVRSSARAEH GAEPPAPEPS
60 70 80 90 100
AGASSNWTTL PPPLFSKVVI VLIDALRDDF VFGSKGVKFM PYTTYLVEKG
110 120 130 140 150
ASHSFVAEAK PPTVTMPRIK ALMTGSLPGF VDVIRNLNSP ALLEDSVIRQ
160 170 180 190 200
AKAAGKRIVF YGDETWVKLF PKHFVEYDGT TSFFVSDYTE VDNNVTRHLD
210 220 230 240 250
KVLKRGDWDI LILHYLGLDH IGHISGPNSP LIGQKLSEMD SVLMKIHTSL
260 270 280 290 300
QSKERETPLP NLLVLCGDHG MSETGSHGAS STEEVNTPLI LISSAFERKP
310 320 330 340 350
GDIRHPKHVQ QTDVAATLAI ALGLPIPKDS VGSLLFPVVE GRPMREQLRF
360 370 380 390 400
LHLNTVQLSK LLQENVPSYE KDPGFEQFKM SERLHGNWIR LYLEEKHSEV
410 420 430 440 450
LFNLGSKVLR QYLDALKTLS LSLSAQVAQY DIYSMMVGTV VVLEVLTLLL
460 470 480 490 500
LSVPQALRRK AELEVPLSSP GFSLLFYLVI LVLSAVHVIV CTSAESSCYF
510 520 530 540 550
CGLSWLAAGG VMVLASALLC VIVSVLTNVL VGGNTPRKNP MHPSSRWSEL
560 570 580 590 600
DLLILLGTAG HVLSLGASSF VEEEHQTWYF LVNTLCLALS QETYRNYFLG
610 620 630 640 650
DDGEPPCGLC VEQGHDGATA AWQDGPGCDV LERDKGHGSP STSEVLRGRE
660 670 680 690 700
KWMVLASPWL ILACCRLLRS LNQTGVQWAH RPDLGHWLTS SDHKAELSVL
710 720 730 740 750
AALSLLVVFV LVQRGCSPVS KAALALGLLG VYCYRAAIGS VRFPWRPDSK
760 770 780 790 800
DISKGIIEAR FVYVFVLGIL FTGTKDLLKS QVIAADFKLK TVGLWEIYSG
810 820 830 840 850
LVLLAALLFR PHNLPVLAFS LLIQTLMTKF IWKPLRHDAA EITVMHYWFG
860 870 880 890 900
QAFFYFQGNS NNIATVDISA GFVGLDTYVE IPAVLLTAFG TYAGPVLWAS
910 920 930 940 950
HLVHFLSSET RSGSALSHAC FCYALICSIP VFTYIVLVTS LRYHLFIWSV
960 970 980
FSPKLLYEGM HLLITAAVCV FFTAMDQTRL TQS
The sequence of this isoform differs from the canonical sequence as follows:
430-463: YDIYSMMVGTVVVLEVLTLLLLSVPQALRRKAEL → FSPCSCSASHRHCTERLSWKSHCHLLGFLCSFIW
464-983: Missing.
Computationally mapped potential isoform sequencesi
There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketE7EWV1 | E7EWV1_HUMAN | GPI ethanolamine phosphate transfer... | PIGG | 894 | Annotation score: | ||
D6RFE8 | D6RFE8_HUMAN | GPI ethanolamine phosphate transfer... | PIGG | 480 | Annotation score: | ||
E7EM50 | E7EM50_HUMAN | GPI ethanolamine phosphate transfer... | PIGG | 463 | Annotation score: | ||
D6R9J9 | D6R9J9_HUMAN | GPI ethanolamine phosphate transfer... | PIGG | 193 | Annotation score: | ||
D6RD39 | D6RD39_HUMAN | GPI ethanolamine phosphate transfer... | PIGG | 186 | Annotation score: | ||
D6RC16 | D6RC16_HUMAN | GPI ethanolamine phosphate transfer... | PIGG | 24 | Annotation score: |
Sequence cautioni
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 624 | D → G in BAC11227 (PubMed:16303743).Curated | 1 | |
Sequence conflicti | 889 | F → L in BAC11227 (PubMed:16303743).Curated | 1 |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_057680 | 55 | S → Y. Corresponds to variant dbSNP:rs34120878EnsemblClinVar. | 1 | |
Natural variantiVAR_027022 | 458 | R → H1 PublicationCorresponds to variant dbSNP:rs13115344Ensembl. | 1 | |
Natural variantiVAR_083080 | 505 | Missing Unknown pathological significance. 1 Publication | 1 | |
Natural variantiVAR_083081 | 538 | K → N Found in SNIBFIS; unknown pathological significance. 1 Publication | 1 | |
Natural variantiVAR_027023 | 610 | C → R1 PublicationCorresponds to variant dbSNP:rs7666425Ensembl. | 1 | |
Natural variantiVAR_076775 | 669 | R → C in MRT53; almost complete loss of ethanolamine phosphate transferase activity, as evidenced by abnormal accumulation of the GPI precursors H7 and H7' and absence of mature GPI precursor H8 in patient lymphocytes; does not affect protein expression levels in transfected HEK293 cells. 1 PublicationCorresponds to variant dbSNP:rs372392424EnsemblClinVar. | 1 | |
Natural variantiVAR_027024 | 699 | V → I2 PublicationsCorresponds to variant dbSNP:rs13114026Ensembl. | 1 | |
Natural variantiVAR_060086 | 731 | V → I. Corresponds to variant dbSNP:rs34916638EnsemblClinVar. | 1 | |
Natural variantiVAR_060087 | 881 | I → T. Corresponds to variant dbSNP:rs34623004Ensembl. | 1 | |
Natural variantiVAR_027025 | 932 | F → S. Corresponds to variant dbSNP:rs1127410Ensembl. | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_054387 | 1 – 122 | Missing in isoform 6. 1 PublicationAdd BLAST | 122 | |
Alternative sequenceiVSP_019827 | 1 – 89 | Missing in isoform 5. 1 PublicationAdd BLAST | 89 | |
Alternative sequenceiVSP_019828 | 120 – 252 | Missing in isoform 3. 1 PublicationAdd BLAST | 133 | |
Alternative sequenceiVSP_019829 | 372 – 388 | DPGFE…LHGNW → GSHPAPAQRPTGTAQKG in isoform 5. 1 PublicationAdd BLAST | 17 | |
Alternative sequenceiVSP_019830 | 389 – 983 | Missing in isoform 5. 1 PublicationAdd BLAST | 595 | |
Alternative sequenceiVSP_019831 | 430 – 463 | YDIYS…RKAEL → FSPCSCSASHRHCTERLSWK SHCHLLGFLCSFIW in isoform 4. 1 PublicationAdd BLAST | 34 | |
Alternative sequenceiVSP_054388 | 430 – 463 | YDIYS…RKAEL → FSPCSCSASHRHCAERLSWK SHCHLLGFLCSFIW in isoform 6. 1 PublicationAdd BLAST | 34 | |
Alternative sequenceiVSP_019832 | 437 – 444 | Missing in isoform 2. 1 Publication | 8 | |
Alternative sequenceiVSP_019833 | 464 – 983 | Missing in isoform 4 and isoform 6. 2 PublicationsAdd BLAST | 520 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB162713 mRNA Translation: BAD89023.1 AY358538 mRNA Translation: AAQ88902.1 Sequence problems. AK074815 mRNA Translation: BAC11227.1 AK000272 mRNA Translation: BAA91046.1 Different initiation. AK027465 mRNA Translation: BAB55130.1 Different initiation. AK097244 mRNA Translation: BAC04984.1 AK296507 mRNA Translation: BAG59139.1 AC092574 Genomic DNA No translation available. AC116565 Genomic DNA No translation available. BC000937 mRNA Translation: AAH00937.2 BC001249 mRNA Translation: AAH01249.2 BC110878 mRNA Translation: AAI10879.1 |
CCDSi | CCDS3336.1 [Q5H8A4-2] CCDS46992.1 [Q5H8A4-1] CCDS75080.1 [Q5H8A4-3] CCDS75083.1 [Q5H8A4-5] |
RefSeqi | NP_001120650.1, NM_001127178.2 [Q5H8A4-1] NP_001275980.1, NM_001289051.1 NP_001275981.1, NM_001289052.1 [Q5H8A4-3] NP_001275984.1, NM_001289055.1 [Q5H8A4-6] NP_001275986.1, NM_001289057.1 [Q5H8A4-5] NP_060203.3, NM_017733.4 [Q5H8A4-2] |
Genome annotation databases
Ensembli | ENST00000310340.9; ENSP00000311750.5; ENSG00000174227.16 [Q5H8A4-2] ENST00000383028.8; ENSP00000372494.4; ENSG00000174227.16 [Q5H8A4-3] ENST00000453061.7; ENSP00000415203.2; ENSG00000174227.16 ENST00000503111.5; ENSP00000426002.1; ENSG00000174227.16 [Q5H8A4-5] |
GeneIDi | 54872 |
KEGGi | hsa:54872 |
MANE-Selecti | ENST00000453061.7; ENSP00000415203.2; NM_001127178.3; NP_001120650.1 |
UCSCi | uc003gaj.6, human [Q5H8A4-1] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB162713 mRNA Translation: BAD89023.1 AY358538 mRNA Translation: AAQ88902.1 Sequence problems. AK074815 mRNA Translation: BAC11227.1 AK000272 mRNA Translation: BAA91046.1 Different initiation. AK027465 mRNA Translation: BAB55130.1 Different initiation. AK097244 mRNA Translation: BAC04984.1 AK296507 mRNA Translation: BAG59139.1 AC092574 Genomic DNA No translation available. AC116565 Genomic DNA No translation available. BC000937 mRNA Translation: AAH00937.2 BC001249 mRNA Translation: AAH01249.2 BC110878 mRNA Translation: AAI10879.1 |
CCDSi | CCDS3336.1 [Q5H8A4-2] CCDS46992.1 [Q5H8A4-1] CCDS75080.1 [Q5H8A4-3] CCDS75083.1 [Q5H8A4-5] |
RefSeqi | NP_001120650.1, NM_001127178.2 [Q5H8A4-1] NP_001275980.1, NM_001289051.1 NP_001275981.1, NM_001289052.1 [Q5H8A4-3] NP_001275984.1, NM_001289055.1 [Q5H8A4-6] NP_001275986.1, NM_001289057.1 [Q5H8A4-5] NP_060203.3, NM_017733.4 [Q5H8A4-2] |
3D structure databases
AlphaFoldDBi | Q5H8A4 |
SMRi | Q5H8A4 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 120220, 109 interactors |
IntActi | Q5H8A4, 11 interactors |
MINTi | Q5H8A4 |
STRINGi | 9606.ENSP00000415203 |
PTM databases
GlyGeni | Q5H8A4, 1 site |
iPTMneti | Q5H8A4 |
PhosphoSitePlusi | Q5H8A4 |
Genetic variation databases
BioMutai | PIGG |
DMDMi | 74707851 |
Proteomic databases
EPDi | Q5H8A4 |
jPOSTi | Q5H8A4 |
MassIVEi | Q5H8A4 |
MaxQBi | Q5H8A4 |
PaxDbi | Q5H8A4 |
PeptideAtlasi | Q5H8A4 |
PRIDEi | Q5H8A4 |
ProteomicsDBi | 4448 62844 [Q5H8A4-1] 62845 [Q5H8A4-2] 62846 [Q5H8A4-3] 62847 [Q5H8A4-4] 62848 [Q5H8A4-5] |
Protocols and materials databases
Antibodypediai | 3105, 10 antibodies from 9 providers |
DNASUi | 54872 |
Genome annotation databases
Ensembli | ENST00000310340.9; ENSP00000311750.5; ENSG00000174227.16 [Q5H8A4-2] ENST00000383028.8; ENSP00000372494.4; ENSG00000174227.16 [Q5H8A4-3] ENST00000453061.7; ENSP00000415203.2; ENSG00000174227.16 ENST00000503111.5; ENSP00000426002.1; ENSG00000174227.16 [Q5H8A4-5] |
GeneIDi | 54872 |
KEGGi | hsa:54872 |
MANE-Selecti | ENST00000453061.7; ENSP00000415203.2; NM_001127178.3; NP_001120650.1 |
UCSCi | uc003gaj.6, human [Q5H8A4-1] |
Organism-specific databases
CTDi | 54872 |
DisGeNETi | 54872 |
GeneCardsi | PIGG |
HGNCi | HGNC:25985, PIGG |
HPAi | ENSG00000174227, Low tissue specificity |
MalaCardsi | PIGG |
MIMi | 616917, phenotype 616918, gene |
neXtProti | NX_Q5H8A4 |
OpenTargetsi | ENSG00000174227 |
Orphaneti | 488635, Early-onset epilepsy-intellectual disability-brain anomalies syndrome 280, Wolf-Hirschhorn syndrome |
PharmGKBi | PA143485575 |
VEuPathDBi | HostDB:ENSG00000174227 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG2125, Eukaryota |
GeneTreei | ENSGT00910000144269 |
HOGENOMi | CLU_055386_0_0_1 |
InParanoidi | Q5H8A4 |
OMAi | RVKFGHD |
OrthoDBi | 848878at2759 |
PhylomeDBi | Q5H8A4 |
TreeFami | TF300609 |
Enzyme and pathway databases
UniPathwayi | UPA00196 |
PathwayCommonsi | Q5H8A4 |
Reactomei | R-HSA-162710, Synthesis of glycosylphosphatidylinositol (GPI) |
SignaLinki | Q5H8A4 |
SIGNORi | Q5H8A4 |
Miscellaneous databases
BioGRID-ORCSi | 54872, 10 hits in 1076 CRISPR screens |
ChiTaRSi | PIGG, human |
GenomeRNAii | 54872 |
Pharosi | Q5H8A4, Tbio |
PROi | PR:Q5H8A4 |
RNActi | Q5H8A4, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000174227, Expressed in lower esophagus muscularis layer and 225 other tissues |
ExpressionAtlasi | Q5H8A4, baseline and differential |
Genevisiblei | Q5H8A4, HS |
Family and domain databases
CDDi | cd16024, GPI_EPT_2, 1 hit |
Gene3Di | 3.40.720.10, 1 hit |
InterProi | View protein in InterPro IPR017850, Alkaline_phosphatase_core_sf IPR002591, Phosphodiest/P_Trfase IPR037674, PIG-G_N IPR039527, PIGG/GPI7 IPR045687, PIGG/GPI7_C |
PANTHERi | PTHR23072, PTHR23072, 1 hit |
Pfami | View protein in Pfam PF01663, Phosphodiest, 1 hit PF19316, PIGO_PIGG, 1 hit |
SUPFAMi | SSF53649, SSF53649, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | PIGG_HUMAN | |
Accessioni | Q5H8A4Primary (citable) accession number: Q5H8A4 Secondary accession number(s): B4DKC7 Q9NXG5 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 25, 2006 |
Last sequence update: | March 1, 2005 | |
Last modified: | May 25, 2022 | |
This is version 139 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Human chromosome 4
Human chromosome 4: entries, gene names and cross-references to MIM - Human entries with genetic variants
List of human entries with genetic variants - Human variants curated from literature reports
Index of human variants curated from literature reports - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families