UniProtKB - Q5H1F4 (RNH2_XANOR)
Protein
Ribonuclease HII
Gene
rnhB
Organism
Xanthomonas oryzae pv. oryzae (strain KACC10331 / KXO85)
Status
Functioni
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.UniRule annotation
Catalytic activityi
- Endonucleolytic cleavage to 5'-phosphomonoester.UniRule annotation EC:3.1.26.4
Cofactori
Mn2+UniRule annotation, Mg2+UniRule annotationNote: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.UniRule annotation
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 47 | Divalent metal cationUniRule annotation | 1 | |
Metal bindingi | 48 | Divalent metal cationUniRule annotation | 1 | |
Metal bindingi | 140 | Divalent metal cationUniRule annotation | 1 |
GO - Molecular functioni
- manganese ion binding Source: UniProtKB-UniRule
- RNA binding Source: InterPro
- RNA-DNA hybrid ribonuclease activity Source: UniProtKB-UniRule
GO - Biological processi
- RNA catabolic process Source: UniProtKB-UniRule
Keywordsi
Molecular function | Endonuclease, Hydrolase, Nuclease |
Ligand | Manganese, Metal-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Ribonuclease HIIUniRule annotation (EC:3.1.26.4UniRule annotation)Short name: RNase HIIUniRule annotation |
Gene namesi | Name:rnhBUniRule annotation Ordered Locus Names:XOO1963 |
Organismi | Xanthomonas oryzae pv. oryzae (strain KACC10331 / KXO85) |
Taxonomic identifieri | 291331 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Xanthomonadales › Xanthomonadaceae › Xanthomonas › |
Proteomesi |
|
Subcellular locationi
- Cytoplasm UniRule annotation
GO - Cellular componenti
- cytoplasm Source: UniProtKB-SubCell
Keywords - Cellular componenti
CytoplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000235790 | 1 – 252 | Ribonuclease HIIAdd BLAST | 252 |
Family & Domainsi
Sequence similaritiesi
Belongs to the RNase HII family.UniRule annotation
Phylogenomic databases
KOi | K03470 |
OMAi | NILHASM |
Family and domain databases
CDDi | cd07182 RNase_HII_bacteria_HII_like, 1 hit |
Gene3Di | 3.30.420.10, 1 hit |
HAMAPi | MF_00052_B RNase_HII_B, 1 hit |
InterProi | View protein in InterPro IPR022898 RNase_HII IPR001352 RNase_HII/HIII IPR024567 RNase_HII/HIII_dom IPR012337 RNaseH-like_sf IPR036397 RNaseH_sf |
PANTHERi | PTHR10954 PTHR10954, 1 hit PTHR10954:SF18 PTHR10954:SF18, 1 hit |
Pfami | View protein in Pfam PF01351 RNase_HII, 1 hit |
SUPFAMi | SSF53098 SSF53098, 1 hit |
i Sequence
Sequence statusi: Complete.
Q5H1F4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MVRSKHMKIL AANAQADSSN TEARQSLLFS QSPIPNAESR LLVAGVDEAG
60 70 80 90 100
RGPLAGPVAV AAVVFDPNKP RINGLDDSKQ LTAERREQLY ARIVDRALSW
110 120 130 140 150
SVVLIDSEEI DRINIYQATM LGMRRAVEGV AHVAGFARID GNRVPKGLPC
160 170 180 190 200
PAEALIGGDA LDRAIMAASI VAKVTRDRLM HELHAQHPEY RFDQHKGYST
210 220 230 240 250
PMHLAALQTH GPCPQHRRSF APVRLALEGR EQGSAAIGDP EQLQVAQLVA
PL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE013598 Genomic DNA Translation: AAW75217.1 |
Genome annotation databases
EnsemblBacteriai | AAW75217; AAW75217; XOO1963 |
KEGGi | xoo:XOO1963 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE013598 Genomic DNA Translation: AAW75217.1 |
3D structure databases
SMRi | Q5H1F4 |
ModBasei | Search... |
Genome annotation databases
EnsemblBacteriai | AAW75217; AAW75217; XOO1963 |
KEGGi | xoo:XOO1963 |
Phylogenomic databases
KOi | K03470 |
OMAi | NILHASM |
Family and domain databases
CDDi | cd07182 RNase_HII_bacteria_HII_like, 1 hit |
Gene3Di | 3.30.420.10, 1 hit |
HAMAPi | MF_00052_B RNase_HII_B, 1 hit |
InterProi | View protein in InterPro IPR022898 RNase_HII IPR001352 RNase_HII/HIII IPR024567 RNase_HII/HIII_dom IPR012337 RNaseH-like_sf IPR036397 RNaseH_sf |
PANTHERi | PTHR10954 PTHR10954, 1 hit PTHR10954:SF18 PTHR10954:SF18, 1 hit |
Pfami | View protein in Pfam PF01351 RNase_HII, 1 hit |
SUPFAMi | SSF53098 SSF53098, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | RNH2_XANOR | |
Accessioni | Q5H1F4Primary (citable) accession number: Q5H1F4 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 16, 2006 |
Last sequence update: | March 1, 2005 | |
Last modified: | May 8, 2019 | |
This is version 76 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Complete proteome, Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families