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Entry version 138 (11 Dec 2019)
Sequence version 3 (10 Jul 2007)
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Protein

Zinc finger protein 789

Gene

ZNF789

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri201 – 223C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri229 – 251C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri257 – 279C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri285 – 307C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri313 – 335C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri341 – 363C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri369 – 391C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri397 – 419C2H2-type 8PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 789
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF789
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000198556.13

Human Gene Nomenclature Database

More...
HGNCi
HGNC:27801 ZNF789

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q5FWF6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
285989

Open Targets

More...
OpenTargetsi
ENSG00000198556

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162410492

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q5FWF6 Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZNF789

Domain mapping of disease mutations (DMDM)

More...
DMDMi
152112419

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002936971 – 425Zinc finger protein 789Add BLAST425

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q5FWF6

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q5FWF6

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q5FWF6

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q5FWF6

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q5FWF6

PeptideAtlas

More...
PeptideAtlasi
Q5FWF6

PRoteomics IDEntifications database

More...
PRIDEi
Q5FWF6

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
1182
62816 [Q5FWF6-1]
62817 [Q5FWF6-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q5FWF6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q5FWF6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000198556 Expressed in 175 organ(s), highest expression level in prostate gland

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q5FWF6 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q5FWF6 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA029500
HPA050793

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q5FWF6, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000331927

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q5FWF6 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q5FWF6

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini11 – 82KRABPROSITE-ProRule annotationAdd BLAST72

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri201 – 223C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri229 – 251C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri257 – 279C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri285 – 307C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri313 – 335C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri341 – 363C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri369 – 391C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri397 – 419C2H2-type 8PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1721 Eukaryota
COG5048 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000163495

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000231475

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q5FWF6

Identification of Orthologs from Complete Genome Data

More...
OMAi
HKQCHPQ

Database of Orthologous Groups

More...
OrthoDBi
1318335at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q5FWF6

TreeFam database of animal gene trees

More...
TreeFami
TF337055

Family and domain databases

Conserved Domains Database

More...
CDDi
cd07765 KRAB_A-box, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 6 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 8 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 5 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 8 hits
PS50157 ZINC_FINGER_C2H2_2, 8 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q5FWF6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MFPPARGKEL LSFEDVAMYF TREEWGHLNW GQKDLYRDVM LENYRNMVLL
60 70 80 90 100
GFQFPKPEMI CQLENWDEQW ILDLPRTGNR KASGSACPGS EARHKMKKLT
110 120 130 140 150
PKQKFSEDLE SYKISVVMQE SAEKLSEKLH KCKEFVDSCR LTFPTSGDEY
160 170 180 190 200
SRGFLQNLNL IQDQNAQTRW KQGRYDEDGK PFNQRSLLLG HERILTRAKS
210 220 230 240 250
YECSECGKVI RRKAWFDQHQ RIHFLENPFE CKVCGQAFRQ RSALTVHKQC
260 270 280 290 300
HLQNKPYRCH DCGKCFRQLA YLVEHKRIHT KEKPYKCSKC EKTFSQNSTL
310 320 330 340 350
IRHQVIHSGE KRHKCLECGK AFGRHSTLLC HQQIHSKPNT HKCSECGQSF
360 370 380 390 400
GRNVDLIQHQ RIHTKEEFFQ CGECGKTFSF KRNLFRHQVI HTGSQPYQCV
410 420
ICGKSFKWHT SFIKHQGTHK GQIST
Length:425
Mass (Da):49,984
Last modified:July 10, 2007 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i00BF9778A9340CFA
GO
Isoform 2 (identifier: Q5FWF6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-95: Missing.

Show »
Length:330
Mass (Da):38,779
Checksum:iC08FB0A7388A5A17
GO
Isoform 3 (identifier: Q5FWF6-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     51-62: GFQFPKPEMICQ → VYFQFDAAIPLC
     63-425: Missing.

Show »
Length:62
Mass (Da):7,480
Checksum:i89FF1A5E271E39A5
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
C9JUE3C9JUE3_HUMAN
Zinc finger protein 789
ZNF789
56Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9J3R7C9J3R7_HUMAN
Zinc finger protein 789
ZNF789
56Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9J487C9J487_HUMAN
Zinc finger protein 789
ZNF789
118Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8WEN0F8WEN0_HUMAN
Zinc finger protein 789
ZNF789
55Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAD18576 differs from that shown. Reason: Frameshift.Curated
The sequence EAL23876 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti398Q → R in BAD18576 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_05290377T → A1 PublicationCorresponds to variant dbSNP:rs6962772Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0265611 – 95Missing in isoform 2. 1 PublicationAdd BLAST95
Alternative sequenceiVSP_04681651 – 62GFQFP…EMICQ → VYFQFDAAIPLC in isoform 3. CuratedAdd BLAST12
Alternative sequenceiVSP_04681763 – 425Missing in isoform 3. CuratedAdd BLAST363

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK131429 mRNA Translation: BAD18576.1 Frameshift.
AC073063 Genomic DNA No translation available.
CH236956 Genomic DNA Translation: EAL23875.1
CH236956 Genomic DNA Translation: EAL23876.1 Sequence problems.
BC089424 mRNA Translation: AAH89424.2

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS34693.1 [Q5FWF6-1]
CCDS34694.1 [Q5FWF6-3]

NCBI Reference Sequences

More...
RefSeqi
NP_001013276.1, NM_001013258.1 [Q5FWF6-3]
NP_998768.2, NM_213603.2 [Q5FWF6-1]
XP_011514375.1, XM_011516073.2 [Q5FWF6-2]
XP_016867507.1, XM_017012018.1 [Q5FWF6-1]
XP_016867514.1, XM_017012025.1
XP_016867515.1, XM_017012026.1
XP_016867516.1, XM_017012027.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000331410; ENSP00000331927; ENSG00000198556 [Q5FWF6-1]
ENST00000379724; ENSP00000369047; ENSG00000198556 [Q5FWF6-3]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
285989

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:285989

UCSC genome browser

More...
UCSCi
uc003uqp.4 human [Q5FWF6-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK131429 mRNA Translation: BAD18576.1 Frameshift.
AC073063 Genomic DNA No translation available.
CH236956 Genomic DNA Translation: EAL23875.1
CH236956 Genomic DNA Translation: EAL23876.1 Sequence problems.
BC089424 mRNA Translation: AAH89424.2
CCDSiCCDS34693.1 [Q5FWF6-1]
CCDS34694.1 [Q5FWF6-3]
RefSeqiNP_001013276.1, NM_001013258.1 [Q5FWF6-3]
NP_998768.2, NM_213603.2 [Q5FWF6-1]
XP_011514375.1, XM_011516073.2 [Q5FWF6-2]
XP_016867507.1, XM_017012018.1 [Q5FWF6-1]
XP_016867514.1, XM_017012025.1
XP_016867515.1, XM_017012026.1
XP_016867516.1, XM_017012027.1

3D structure databases

SMRiQ5FWF6
ModBaseiSearch...

Protein-protein interaction databases

IntActiQ5FWF6, 1 interactor
STRINGi9606.ENSP00000331927

PTM databases

iPTMnetiQ5FWF6
PhosphoSitePlusiQ5FWF6

Polymorphism and mutation databases

BioMutaiZNF789
DMDMi152112419

Proteomic databases

EPDiQ5FWF6
jPOSTiQ5FWF6
MassIVEiQ5FWF6
MaxQBiQ5FWF6
PaxDbiQ5FWF6
PeptideAtlasiQ5FWF6
PRIDEiQ5FWF6
ProteomicsDBi1182
62816 [Q5FWF6-1]
62817 [Q5FWF6-2]

Genome annotation databases

EnsembliENST00000331410; ENSP00000331927; ENSG00000198556 [Q5FWF6-1]
ENST00000379724; ENSP00000369047; ENSG00000198556 [Q5FWF6-3]
GeneIDi285989
KEGGihsa:285989
UCSCiuc003uqp.4 human [Q5FWF6-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
285989
DisGeNETi285989
EuPathDBiHostDB:ENSG00000198556.13

GeneCards: human genes, protein and diseases

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GeneCardsi
ZNF789
HGNCiHGNC:27801 ZNF789
HPAiHPA029500
HPA050793
neXtProtiNX_Q5FWF6
OpenTargetsiENSG00000198556
PharmGKBiPA162410492

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00940000163495
HOGENOMiHOG000231475
InParanoidiQ5FWF6
OMAiHKQCHPQ
OrthoDBi1318335at2759
PhylomeDBiQ5FWF6
TreeFamiTF337055

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
ZNF789 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
285989
PharosiQ5FWF6 Tdark

Protein Ontology

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PROi
PR:Q5FWF6
RNActiQ5FWF6 protein

Gene expression databases

BgeeiENSG00000198556 Expressed in 175 organ(s), highest expression level in prostate gland
ExpressionAtlasiQ5FWF6 baseline and differential
GenevisibleiQ5FWF6 HS

Family and domain databases

CDDicd07765 KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 6 hits
SMARTiView protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 8 hits
SUPFAMiSSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 5 hits
PROSITEiView protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 8 hits
PS50157 ZINC_FINGER_C2H2_2, 8 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN789_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5FWF6
Secondary accession number(s): A4D282, A6NH61, Q6ZMZ9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: July 10, 2007
Last modified: December 11, 2019
This is version 138 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
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