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UniProtKB - Q5FVT6 (Q5FVT6_RAT)
Protein
Submitted name:
Klf15 protein
Gene
Klf15
Organism
Rattus norvegicus (Rat)
Status
Functioni
GO - Molecular functioni
- DNA binding Source: RGD
- DNA-binding transcription activator activity, RNA polymerase II-specific Source: RGD
- DNA-binding transcription factor activity Source: RGD
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: GO_Central
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: RGD
- RNA polymerase II transcription regulatory region sequence-specific DNA binding Source: RGD
- sequence-specific double-stranded DNA binding Source: RGD
- transcription cis-regulatory region binding Source: RGD
GO - Biological processi
- cardiac muscle hypertrophy in response to stress Source: RGD
- cellular glucose homeostasis Source: RGD
- cellular response to peptide Source: RGD
- glial cell differentiation Source: RGD
- glomerular visceral epithelial cell differentiation Source: RGD
- negative regulation of peptidyl-lysine acetylation Source: RGD
- positive regulation of glucose import Source: RGD
- positive regulation of transcription, DNA-templated Source: RGD
- positive regulation of transcription by RNA polymerase II Source: RGD
- regulation of gene expression Source: RGD
- regulation of transcription by RNA polymerase II Source: GO_Central
- regulation of Wnt signaling pathway Source: RGD
- response to insulin Source: RGD
Keywordsi
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: Klf15 proteinImportedSubmitted name: Kruppel-like factor 15ImportedSubmitted name: Kruppel-like factor 15, isoform CRA_aImported |
Gene namesi | Name:Klf15Imported ORF Names:rCG_56332Imported |
Organismi | Rattus norvegicus (Rat)Imported |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 70918, Klf15 |
Expressioni
Gene expression databases
Bgeei | ENSRNOG00000017808, Expressed in liver and 22 other tissues |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 320 – 349 | C2H2-typeInterPro annotationAdd BLAST | 30 | |
Domaini | 350 – 379 | C2H2-typeInterPro annotationAdd BLAST | 30 | |
Domaini | 380 – 407 | C2H2-typeInterPro annotationAdd BLAST | 28 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 151 – 216 | DisorderedSequence analysisAdd BLAST | 66 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 164 – 178 | Polar residuesSequence analysisAdd BLAST | 15 |
Keywords - Domaini
Zinc-fingerPROSITE-ProRule annotationPhylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000156977 |
HOGENOMi | CLU_035818_0_0_1 |
OMAi | SGRAYHM |
OrthoDBi | 891966at2759 |
TreeFami | TF350556 |
Family and domain databases
InterProi | View protein in InterPro IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF00096, zf-C2H2, 3 hits |
SMARTi | View protein in SMART SM00355, ZnF_C2H2, 3 hits |
SUPFAMi | SSF57667, SSF57667, 2 hits |
PROSITEi | View protein in PROSITE PS00028, ZINC_FINGER_C2H2_1, 3 hits PS50157, ZINC_FINGER_C2H2_2, 3 hits |
i Sequence
Sequence statusi: Complete.
Q5FVT6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MVDHLLPVDE TFSSPKCPVG YLGDRLASRQ PYHMLPSPIS EDDSDVSSPC
60 70 80 90 100
SCASPDSQAF CSCYSAGPGP EAQGSILDFL LSRATLGSGG ASGGVGDGSG
110 120 130 140 150
PVTWGSWRRA SVPVKEEHLC FPEFLSGDPD DVSRPFQPTL EEIEEFLEEN
160 170 180 190 200
MEAEVKEAPE SSSRDLEACS QLSAGSHRSH LHPESGGREC RTPPPGGTSG
210 220 230 240 250
GGTQGAGEGS AHDGPMPVLL QIQPVAVKQE AGAGPASPGQ APESVKVAQL
260 270 280 290 300
LVNIQGQTFA LLPQVVPSSN LNLSSKFVRI APVPIAAKPI GSGSLGPGPA
310 320 330 340 350
GLLVGQKFPK NPAAELLKMH KCTFPGCSKM YTKSSHLKAH LRRHTGEKPF
360 370 380 390 400
ACTWPGCGWR FSRSDELSRH RRSHSGVKPY QCPVCEKKFA RSDHLSKHIK
410
VHRFPRSSRA VRAIN
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AABR07061416 Genomic DNA No translation available. BC089782 mRNA Translation: AAH89782.1 AB102791 mRNA Translation: BAG30822.1 AB102792 mRNA Translation: BAG30823.1 CH473957 Genomic DNA Translation: EDL91352.1 CH473957 Genomic DNA Translation: EDL91353.1 CH473957 Genomic DNA Translation: EDL91354.1 |
RefSeqi | NP_445988.1, NM_053536.1 XP_006236944.1, XM_006236882.3 XP_006236946.1, XM_006236884.3 XP_008761357.1, XM_008763135.2 XP_008761358.1, XM_008763136.1 XP_017448423.1, XM_017592934.1 |
Genome annotation databases
Ensembli | ENSRNOT00000024011; ENSRNOP00000024011; ENSRNOG00000017808 |
GeneIDi | 85497 |
KEGGi | rno:85497 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AABR07061416 Genomic DNA No translation available. BC089782 mRNA Translation: AAH89782.1 AB102791 mRNA Translation: BAG30822.1 AB102792 mRNA Translation: BAG30823.1 CH473957 Genomic DNA Translation: EDL91352.1 CH473957 Genomic DNA Translation: EDL91353.1 CH473957 Genomic DNA Translation: EDL91354.1 |
RefSeqi | NP_445988.1, NM_053536.1 XP_006236944.1, XM_006236882.3 XP_006236946.1, XM_006236884.3 XP_008761357.1, XM_008763135.2 XP_008761358.1, XM_008763136.1 XP_017448423.1, XM_017592934.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 10116.ENSRNOP00000024011 |
Genome annotation databases
Ensembli | ENSRNOT00000024011; ENSRNOP00000024011; ENSRNOG00000017808 |
GeneIDi | 85497 |
KEGGi | rno:85497 |
Organism-specific databases
CTDi | 28999 |
RGDi | 70918, Klf15 |
Phylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000156977 |
HOGENOMi | CLU_035818_0_0_1 |
OMAi | SGRAYHM |
OrthoDBi | 891966at2759 |
TreeFami | TF350556 |
Gene expression databases
Bgeei | ENSRNOG00000017808, Expressed in liver and 22 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF00096, zf-C2H2, 3 hits |
SMARTi | View protein in SMART SM00355, ZnF_C2H2, 3 hits |
SUPFAMi | SSF57667, SSF57667, 2 hits |
PROSITEi | View protein in PROSITE PS00028, ZINC_FINGER_C2H2_1, 3 hits PS50157, ZINC_FINGER_C2H2_2, 3 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | Q5FVT6_RAT | |
Accessioni | Q5FVT6Primary (citable) accession number: Q5FVT6 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | March 1, 2005 |
Last sequence update: | March 1, 2005 | |
Last modified: | January 19, 2022 | |
This is version 129 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |