Klf15

Functionⁱ

GO - Molecular functionⁱ

DNA-binding transcription factor activity, RNA polymerase II-specific
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
transcription regulatory region DNA binding Source: Ensembl

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

cardiac muscle hypertrophy in response to stress Source: Ensembl
cellular response to peptide
Source: RGD
Inferred from expression patternⁱ
- 18406357
glial cell differentiation Source: Ensembl
glomerular visceral epithelial cell differentiation Source: Ensembl
negative regulation of peptidyl-lysine acetylation Source: Ensembl
positive regulation of glucose import in response to insulin stimulus Source: Ensembl
positive regulation of transcription, DNA-templated Source: Ensembl
regulation of transcription by RNA polymerase II
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Ligand	Metal-binding, Zinc

Ligand

Metal-binding, Zinc

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Klf15 proteinImported Submitted name: Kruppel-like factor 15Imported Submitted name: Kruppel-like factor 15, isoform CRA_aImported
Gene namesⁱ	Name:Klf15Imported ORF Names:rCG_56332Imported
Organismⁱ	Rattus norvegicus (Rat)Imported
Taxonomic identifierⁱ	10116 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus
Proteomesⁱ	UP000002494 Componentⁱ: Chromosome 4

Organism-specific databases

Rat genome database More...RGDⁱ	70918 Klf15

RGDⁱ

70918 Klf15

Subcellular locationⁱ

GO - Cellular component

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSRNOG00000017808 Expressed in 9 organ(s), highest expression level in liver

Bgeeⁱ

ENSRNOG00000017808 Expressed in 9 organ(s), highest expression level in liver

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000024011

STRINGⁱ

10116.ENSRNOP00000024011

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Domainⁱ	320 – 349	C2H2-typeInterPro annotationAdd BLAST	30
Domainⁱ	350 – 379	C2H2-typeInterPro annotationAdd BLAST	30
Domainⁱ	380 – 407	C2H2-typeInterPro annotationAdd BLAST	28

Keywords - Domainⁱ

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGⁱ	KOG1721 Eukaryota COG5048 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000118998
HOGENOMⁱ	HOG000294058
HOVERGENⁱ	HBG052266
OMAⁱ	QDSILDY
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G09JN
TreeFamⁱ	TF350556

Family and domain databases

InterProⁱ	View protein in InterPro IPR036236 Znf_C2H2_sf IPR013087 Znf_C2H2_type
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00096 zf-C2H2, 3 hits
SMARTⁱ	View protein in SMART SM00355 ZnF_C2H2, 3 hits
SUPFAMⁱ	SSF57667 SSF57667, 2 hits
PROSITEⁱ	View protein in PROSITE PS00028 ZINC_FINGER_C2H2_1, 3 hits PS50157 ZINC_FINGER_C2H2_2, 3 hits

Sequenceⁱ

Sequence statusⁱ: Complete.

Q5FVT6-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MVDHLLPVDE TFSSPKCPVG YLGDRLASRQ PYHMLPSPIS EDDSDVSSPC 
        60         70         80         90        100
SCASPDSQAF CSCYSAGPGP EAQGSILDFL LSRATLGSGG ASGGVGDGSG 
       110        120        130        140        150
PVTWGSWRRA SVPVKEEHLC FPEFLSGDPD DVSRPFQPTL EEIEEFLEEN 
       160        170        180        190        200
MEAEVKEAPE SSSRDLEACS QLSAGSHRSH LHPESGGREC RTPPPGGTSG 
       210        220        230        240        250
GGTQGAGEGS AHDGPMPVLL QIQPVAVKQE AGAGPASPGQ APESVKVAQL 
       260        270        280        290        300
LVNIQGQTFA LLPQVVPSSN LNLSSKFVRI APVPIAAKPI GSGSLGPGPA 
       310        320        330        340        350
GLLVGQKFPK NPAAELLKMH KCTFPGCSKM YTKSSHLKAH LRRHTGEKPF 
       360        370        380        390        400
ACTWPGCGWR FSRSDELSRH RRSHSGVKPY QCPVCEKKFA RSDHLSKHIK 
       410 
VHRFPRSSRA VRAIN

Length:415

Mass (Da):44,136

Last modified:March 1, 2005 - v1

Checksum:ⁱA913F46DDBE9253D

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AABR07061416 Genomic DNA No translation available. BC089782 mRNA Translation: AAH89782.1 AB102791 mRNA Translation: BAG30822.1 AB102792 mRNA Translation: BAG30823.1 CH473957 Genomic DNA Translation: EDL91352.1 CH473957 Genomic DNA Translation: EDL91353.1 CH473957 Genomic DNA Translation: EDL91354.1
NCBI Reference Sequences More...RefSeqⁱ	XP_006236944.1, XM_006236882.3 XP_006236946.1, XM_006236884.3 XP_008761357.1, XM_008763135.2 XP_008761358.1, XM_008763136.1 XP_017448423.1, XM_017592934.1
UniGeneⁱ	Rn.22556

Genome annotation databases

Ensemblⁱ	ENSRNOT00000024011; ENSRNOP00000024011; ENSRNOG00000017808
GeneIDⁱ	85497

Protein	Similar proteins		Species	Score	Length	Source
Q5FVT6	Krueppel-like factor 15		MESAU		415	UniRef90_Q5FVT6
Kruppel-like transcription factor		RAT		415
Krueppel-like factor 15		CRIGR		414
UPI00038C4D6F		MICOH		415
UPI00042A990C		PERMB		415
+2

Protein	Similar proteins		Species	Score	Length	Source
Q5FVT6	Krueppel-like factor 15		MESAU		415	UniRef50_Q5FVT6
Kruppel-like transcription factor		RAT		415
Krueppel-like factor 15		CRIGR		414
Kruppel like factor 15		HORSE		399
Kruppel like factor 15		SARHA		397
+29

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AABR07061416 Genomic DNA No translation available. BC089782 mRNA Translation: AAH89782.1 AB102791 mRNA Translation: BAG30822.1 AB102792 mRNA Translation: BAG30823.1 CH473957 Genomic DNA Translation: EDL91352.1 CH473957 Genomic DNA Translation: EDL91353.1 CH473957 Genomic DNA Translation: EDL91354.1
RefSeqⁱ	XP_006236944.1, XM_006236882.3 XP_006236946.1, XM_006236884.3 XP_008761357.1, XM_008763135.2 XP_008761358.1, XM_008763136.1 XP_017448423.1, XM_017592934.1
UniGeneⁱ	Rn.22556

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000024011

STRINGⁱ

10116.ENSRNOP00000024011

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSRNOT00000024011; ENSRNOP00000024011; ENSRNOG00000017808
GeneIDⁱ	85497

Organism-specific databases

CTDⁱ	28999
RGDⁱ	70918 Klf15

Phylogenomic databases

eggNOGⁱ	KOG1721 Eukaryota COG5048 LUCA
GeneTreeⁱ	ENSGT00760000118998
HOGENOMⁱ	HOG000294058
HOVERGENⁱ	HBG052266
OMAⁱ	QDSILDY
OrthoDBⁱ	EOG091G09JN
TreeFamⁱ	TF350556

Gene expression databases

Bgeeⁱ	ENSRNOG00000017808 Expressed in 9 organ(s), highest expression level in liver

Bgeeⁱ

ENSRNOG00000017808 Expressed in 9 organ(s), highest expression level in liver

Family and domain databases

InterProⁱ	View protein in InterPro IPR036236 Znf_C2H2_sf IPR013087 Znf_C2H2_type
Pfamⁱ	View protein in Pfam PF00096 zf-C2H2, 3 hits
SMARTⁱ	View protein in SMART SM00355 ZnF_C2H2, 3 hits
SUPFAMⁱ	SSF57667 SSF57667, 2 hits
PROSITEⁱ	View protein in PROSITE PS00028 ZINC_FINGER_C2H2_1, 3 hits PS50157 ZINC_FINGER_C2H2_2, 3 hits
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q5FVT6_RAT
Accessionⁱ	Q5FVT6Primary (citable) accession number: Q5FVT6
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	March 1, 2005
	Last sequence update:	March 1, 2005
	Last modified:	November 7, 2018
	This is version 112 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB - Q5FVT6 (Q5FVT6_RAT)

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Klf15 protein

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Keywordsⁱ

Names & Taxonomyⁱ

Organism-specific databases

Subcellular locationⁱ

Nucleus

Expressionⁱ

Gene expression databases

Interactionⁱ

Protein-protein interaction databases

Family & Domainsⁱ

Domains and Repeats

Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

UniProt is an ELIXIR core data resource

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q5FVT6 (Q5FVT6_RAT)

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Klf15 protein

Klf15

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

UniProt is an ELIXIR core data resource

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Expressionⁱ

Interactionⁱ

Family & Domainsⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ