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Protein
Submitted name:

ATP-binding cassette subfamily B member 10

Gene

Abcb10

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi492 – 499ATPPROSITE-ProRule annotation8

GO - Molecular functioni

Keywordsi

LigandATP-bindingPROSITE-ProRule annotationImported, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-RNO-1369007 Mitochondrial ABC transporters

Names & Taxonomyi

Protein namesi
Submitted name:
ATP-binding cassette subfamily B member 10Imported
Submitted name:
ATP-binding cassette, sub-family B (MDR/TAP), member 10Imported
Gene namesi
Name:Abcb10Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 19

Organism-specific databases

RGDi1311222 Abcb10

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei136 – 156HelicalSequence analysisAdd BLAST21
Transmembranei176 – 200HelicalSequence analysisAdd BLAST25
Transmembranei282 – 301HelicalSequence analysisAdd BLAST20
Transmembranei357 – 379HelicalSequence analysisAdd BLAST23
Transmembranei399 – 420HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PRIDEiQ5FVL8

Expressioni

Gene expression databases

BgeeiENSRNOG00000017993 Expressed in 9 organ(s), highest expression level in skeletal muscle tissue

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000024232

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini138 – 422ABC transmembrane type-1InterPro annotationAdd BLAST285
Domaini457 – 696ABC transporterInterPro annotationAdd BLAST240

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0058 Eukaryota
COG1132 LUCA
GeneTreeiENSGT00550000074497
HOVERGENiHBG008358
KOiK05657
OMAiMLIDPIS
OrthoDBiEOG091G0HVA
TreeFamiTF105198

Family and domain databases

Gene3Di1.20.1560.10, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR011527 ABC1_TM_dom
IPR036640 ABC1_TM_sf
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR030260 ABCB10-like
IPR027417 P-loop_NTPase
PANTHERiPTHR24221:SF392 PTHR24221:SF392, 1 hit
PfamiView protein in Pfam
PF00664 ABC_membrane, 1 hit
PF00005 ABC_tran, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
SSF90123 SSF90123, 1 hit
PROSITEiView protein in PROSITE
PS50929 ABC_TM1F, 1 hit
PS00211 ABC_TRANSPORTER_1, 1 hit
PS50893 ABC_TRANSPORTER_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q5FVL8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRAPPARALL LFPRRGPAVR AWAPAVSSRT WLASEWTPLV RAWTSLIHEP
60 70 80 90 100
SPGLRFPVPL SGLPGGVGRW ATSSGIRRCW VLAGPRAAHP LFARLQGAAA
110 120 130 140 150
TGVRDLGNDS QRRPATTGRS EVWKLLGLVR PERGRLSAAV GFLAVSSVIT
160 170 180 190 200
MSAPFFLGKI IDVIYTNPTE DFGDSLTRLC AGLTCVFLCG AAANSIRVYL
210 220 230 240 250
MQSSGQSIVN RLRTSLFSSI LRQEVAFFDK TRTGELINRL SSDTALLGHS
260 270 280 290 300
VTENLSDGLR AVAQASVGVG MMFFVSPSLA TFVLSVVPPI SVLAVIYGRY
310 320 330 340 350
LRKLSKATQD SLAEATQLAE ERIGNIRTIR AFGKEMTEVE KYTSRVDQLL
360 370 380 390 400
QLARKEALAR AGFFGAAGLS GNLIVLSVLY KGGLLLGSTH MTVGELSSFL
410 420 430 440 450
MYAFWVGLSI GGLSSFYSQL MKGLGAGGRL WELLERQPRL PFNEGIVLDE
460 470 480 490 500
KTFQGALEFR NVHFTYPARP EVSVFQDFSL SIPSGSVTAL VGPSGSGKST
510 520 530 540 550
VVSLLLRLYD PSSGTVSLDG HDIRQLNPVW LRSKIGTVSQ EPVLFSCSVA
560 570 580 590 600
ENIAYGADNL SSVTARQVER AAEVANAAEF IRSFPQGFDT VVGEKGVLLS
610 620 630 640 650
GGQKQRIAIA RALLKNPKIL LLDEATSALD AENEHLVQEA LDRLMEGRTV
660 670 680 690 700
LIIAHRLSTI KNANFVAVLN QGKICEHGTH EELLLKPNGL YRKLMNKQSL
710
LLHNGAEQFL EPAQA
Length:715
Mass (Da):77,394
Last modified:March 1, 2005 - v1
Checksum:i0E609BB87907E7E9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC133405 Genomic DNA No translation available.
BC089900 mRNA Translation: AAH89900.1
RefSeqiNP_001012166.1, NM_001012166.1
UniGeneiRn.22937

Genome annotation databases

EnsembliENSRNOT00000024232; ENSRNOP00000024232; ENSRNOG00000017993
GeneIDi361439
KEGGirno:361439
UCSCiRGD:1311222 rat

Similar proteinsi

Entry informationi

Entry nameiQ5FVL8_RAT
AccessioniPrimary (citable) accession number: Q5FVL8
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2005
Last sequence update: March 1, 2005
Last modified: September 12, 2018
This is version 120 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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