UniProtKB - Q5FNP1 (UVRC_GLUOX)
Protein
UvrABC system protein C
Gene
uvrC
Organism
Gluconobacter oxydans (strain 621H) (Gluconobacter suboxydans)
Status
Functioni
The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.UniRule annotation
GO - Molecular functioni
- DNA binding Source: UniProtKB-UniRule
- excinuclease ABC activity Source: UniProtKB-UniRule
GO - Biological processi
- nucleotide-excision repair Source: UniProtKB-UniRule
- SOS response Source: UniProtKB-UniRule
Keywordsi
Molecular function | Excision nuclease |
Biological process | DNA damage, DNA excision, DNA repair, SOS response |
Names & Taxonomyi
Protein namesi | Recommended name: UvrABC system protein CUniRule annotationShort name: Protein UvrCUniRule annotation Alternative name(s): Excinuclease ABC subunit CUniRule annotation |
Gene namesi | Name:uvrCUniRule annotation Ordered Locus Names:GOX2273 |
Organismi | Gluconobacter oxydans (strain 621H) (Gluconobacter suboxydans) |
Taxonomic identifieri | 290633 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Alphaproteobacteria › Rhodospirillales › Acetobacteraceae › Gluconobacter › |
Proteomesi |
|
Subcellular locationi
Cytoplasm and Cytosol
- Cytoplasm UniRule annotation
Other locations
- cytoplasm Source: UniProtKB-SubCell
- excinuclease repair complex Source: InterPro
Keywords - Cellular componenti
CytoplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000264897 | 1 – 645 | UvrABC system protein CAdd BLAST | 645 |
Interactioni
Subunit structurei
Interacts with UvrB in an incision complex.
UniRule annotationProtein-protein interaction databases
STRINGi | 290633.GOX2273 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 40 – 118 | GIY-YIGUniRule annotationAdd BLAST | 79 | |
Domaini | 228 – 263 | UVRUniRule annotationAdd BLAST | 36 |
Sequence similaritiesi
Belongs to the UvrC family.UniRule annotation
Phylogenomic databases
eggNOGi | COG0322, Bacteria |
HOGENOMi | CLU_014841_3_0_5 |
OMAi | LFPIRQC |
Family and domain databases
Gene3Di | 3.30.420.340, 1 hit 3.40.1440.10, 1 hit |
HAMAPi | MF_00203, UvrC, 1 hit |
InterProi | View protein in InterPro IPR041663, DisA/LigA_HHH IPR000305, GIY-YIG_endonuc IPR035901, GIY-YIG_endonuc_sf IPR003583, Hlx-hairpin-Hlx_DNA-bd_motif IPR010994, RuvA_2-like IPR001943, UVR_dom IPR036876, UVR_dom_sf IPR004791, UvrC IPR001162, UvrC_homol_region IPR038476, UvrC_homol_region_sf |
Pfami | View protein in Pfam PF01541, GIY-YIG, 1 hit PF12826, HHH_2, 1 hit PF02151, UVR, 1 hit PF08459, UvrC_HhH_N, 1 hit |
SMARTi | View protein in SMART SM00465, GIYc, 1 hit SM00278, HhH1, 2 hits |
SUPFAMi | SSF46600, SSF46600, 1 hit SSF47781, SSF47781, 1 hit SSF82771, SSF82771, 1 hit |
TIGRFAMsi | TIGR00194, uvrC, 1 hit |
PROSITEi | View protein in PROSITE PS50164, GIY_YIG, 1 hit PS50151, UVR, 1 hit PS50165, UVRC, 1 hit |
i Sequence
Sequence statusi: Complete.
Q5FNP1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTDLPPHSSH HPADQGEPLV PAEKKQGVEA IREALKTIPY SPGVYRMLSE
60 70 80 90 100
KGEVLYVGKA LSLKKRVSSY IRINQLPERL RRMVSMTVSM EIVITRTEAD
110 120 130 140 150
ALLLEANYIK RMKPRFNILL RDDKSYPWLM LTESHEFPQI TKQRGKPVKG
160 170 180 190 200
ATYWGPFANA WAVNQTLNLV QRSFLLRSCS DAVLNSRTRP CLLYQIKRCS
210 220 230 240 250
APCVDRISKE DYAELVSEAR QFLSGHSTEL QQRLVAEMEQ ASQELNYERA
260 270 280 290 300
ASIRDRIRGF ASIQGSSTIN PTSINDADIM TIWQEAGQSC IQVFFIRGSR
310 320 330 340 350
NNGNRAFYPA HAEEETAADV LSAFMIQFYD NKPPPPSILV NCELPEPKLV
360 370 380 390 400
EEALSIRRGQ KVEILRPQRG EKKDVVEHAA LNAREALERK LAENTGQRRL
410 420 430 440 450
LEGVAEVFGL PEIPQRIETY DNSHIMGQAP YGVMVVGGPE GFNKRAYRKY
460 470 480 490 500
AIKGPVTPGD DFGMMREVME RRFGHRSENG ERPEDWPDLL LIDGGLGQFN
510 520 530 540 550
AVRAVLADLG VTGIPIVAIA KGPDRDAGRE WFFTETKSPF QLPPRDPVLY
560 570 580 590 600
YLQRLRDEAH RFAITTHRAG RSKGLRSSEL DHVPGIGAAR KKALLNHFGS
610 620 630 640
AKSVRQASLE ELENAPGISS STATAIYGHF HPEWVQKTSA DNRSH
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP000009 Genomic DNA Translation: AAW62006.1 |
RefSeqi | WP_011253776.1, NZ_LT900338.1 |
Genome annotation databases
EnsemblBacteriai | AAW62006; AAW62006; GOX2273 |
KEGGi | gox:GOX2273 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP000009 Genomic DNA Translation: AAW62006.1 |
RefSeqi | WP_011253776.1, NZ_LT900338.1 |
3D structure databases
SMRi | Q5FNP1 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 290633.GOX2273 |
Genome annotation databases
EnsemblBacteriai | AAW62006; AAW62006; GOX2273 |
KEGGi | gox:GOX2273 |
Phylogenomic databases
eggNOGi | COG0322, Bacteria |
HOGENOMi | CLU_014841_3_0_5 |
OMAi | LFPIRQC |
Family and domain databases
Gene3Di | 3.30.420.340, 1 hit 3.40.1440.10, 1 hit |
HAMAPi | MF_00203, UvrC, 1 hit |
InterProi | View protein in InterPro IPR041663, DisA/LigA_HHH IPR000305, GIY-YIG_endonuc IPR035901, GIY-YIG_endonuc_sf IPR003583, Hlx-hairpin-Hlx_DNA-bd_motif IPR010994, RuvA_2-like IPR001943, UVR_dom IPR036876, UVR_dom_sf IPR004791, UvrC IPR001162, UvrC_homol_region IPR038476, UvrC_homol_region_sf |
Pfami | View protein in Pfam PF01541, GIY-YIG, 1 hit PF12826, HHH_2, 1 hit PF02151, UVR, 1 hit PF08459, UvrC_HhH_N, 1 hit |
SMARTi | View protein in SMART SM00465, GIYc, 1 hit SM00278, HhH1, 2 hits |
SUPFAMi | SSF46600, SSF46600, 1 hit SSF47781, SSF47781, 1 hit SSF82771, SSF82771, 1 hit |
TIGRFAMsi | TIGR00194, uvrC, 1 hit |
PROSITEi | View protein in PROSITE PS50164, GIY_YIG, 1 hit PS50151, UVR, 1 hit PS50165, UVRC, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | UVRC_GLUOX | |
Accessioni | Q5FNP1Primary (citable) accession number: Q5FNP1 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | December 12, 2006 |
Last sequence update: | March 1, 2005 | |
Last modified: | December 2, 2020 | |
This is version 88 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families