UniProtKB - Q5F3H0 (Q5F3H0_CHICK)
Protein
Fanconi anemia group C protein homolog
Gene
RCJMB04_17e13
Organism
Gallus gallus (Chicken)
Status
Functioni
DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1.UniRule annotation
GO - Biological processi
- interstrand cross-link repair Source: InterPro
Keywordsi
Biological process | DNA damage, DNA repairUniRule annotation |
Names & Taxonomyi
Protein namesi | Recommended name: Fanconi anemia group C protein homologUniRule annotationShort name: Protein FACCUniRule annotation |
Gene namesi | ORF Names:RCJMB04_17e13Imported |
Organismi | Gallus gallus (Chicken)Imported |
Taxonomic identifieri | 9031 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Archelosauria › Archosauria › Dinosauria › Saurischia › Theropoda › Coelurosauria › Aves › Neognathae › Galloanserae › Galliformes › Phasianidae › Phasianinae › Gallus |
Subcellular locationi
Nucleus
- Nucleus UniRule annotation
Nucleus
- Fanconi anaemia nuclear complex Source: UniProtKB-UniRule
Other locations
- cytoplasm Source: UniProtKB-KW
Keywords - Cellular componenti
CytoplasmUniRule annotation, NucleusUniRule annotationInteractioni
Subunit structurei
Belongs to the multisubunit FA complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. This complex may also include HSP70.
UniRule annotationFamily & Domainsi
Phylogenomic databases
OrthoDBi | 1546359at2759 |
PhylomeDBi | Q5F3H0 |
Family and domain databases
InterProi | View protein in InterPro IPR000686, FANCC |
PANTHERi | PTHR16798, PTHR16798, 1 hit |
Pfami | View protein in Pfam PF02106, Fanconi_C, 1 hit |
PIRSFi | PIRSF018417, FACC_protein, 1 hit |
PRINTSi | PR00494, FANCONICGENE |
i Sequence
Sequence statusi: Complete.
Q5F3H0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAQDTTVPKL NFKFWLDKAI EWGQDTTLES QKDVCLHLPQ LQEFLHQTYE
60 70 80 90 100
TLKHMNSIAA IQQFPLIGQL LGRLCWNPFV VGYDESQKTL MWCLCCLYSS
110 120 130 140 150
EPQNPVELKA NSWIRSLLCH LLSSSKWERI EAETSTFISA LGYTSADYYC
160 170 180 190 200
HLVENIVSSL VTELRENQFN ELNIQERISV SRVNAVSLFC LPLITLPDLT
210 220 230 240 250
PLLETLLLYH GGASKEILSS EFLEAVNDAV LKKKISLSES AIFSLWHRHL
260 270 280 290 300
PSLESATLSL LDQLTSLQIN SLEKVACVIK DSLLPQAASH PAIFRIVNEI
310 320 330 340 350
FKNALLETDG APEVMTIIQV FIQLFIQVQQ NENKQHKFPL KAYFPHHHQP
360 370 380 390 400
LVIALLRRPF ELPSTHWLQH LKHISDTLKS IVEDTNVSSF ADLYEIWFLV
410 420 430 440 450
ACFGEWLDIA AEQLMKAAVA PDALLWLLAF YYCPQNENQQ RTQTMVESQA
460 470 480 490 500
VYSRLMMLYN RTVLSFGDLQ ASVNNAADTE QCHTQCLITH LLTNFLLFSS
510 520 530 540 550
GGHMIAQEFI SHITETTDMS KEVCSLLIRT AYRIKHNGGE NQRTVKLLNE
LLQKLAVEV
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AJ851680 mRNA Translation: CAH65314.1 |
RefSeqi | NP_001006587.2, NM_001006587.2 |
Genome annotation databases
GeneIDi | 427468 |
KEGGi | gga:427468 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AJ851680 mRNA Translation: CAH65314.1 |
RefSeqi | NP_001006587.2, NM_001006587.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
GeneIDi | 427468 |
KEGGi | gga:427468 |
Organism-specific databases
CTDi | 2176 |
Phylogenomic databases
OrthoDBi | 1546359at2759 |
PhylomeDBi | Q5F3H0 |
Family and domain databases
InterProi | View protein in InterPro IPR000686, FANCC |
PANTHERi | PTHR16798, PTHR16798, 1 hit |
Pfami | View protein in Pfam PF02106, Fanconi_C, 1 hit |
PIRSFi | PIRSF018417, FACC_protein, 1 hit |
PRINTSi | PR00494, FANCONICGENE |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q5F3H0_CHICK | |
Accessioni | Q5F3H0Primary (citable) accession number: Q5F3H0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | March 15, 2005 |
Last sequence update: | March 15, 2005 | |
Last modified: | December 2, 2020 | |
This is version 73 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |