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Entry version 74 (16 Oct 2019)
Sequence version 1 (15 Mar 2005)
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Protein

Protein strawberry notch homolog 1

Gene

SBNO1

Organism
Gallus gallus (Chicken)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein strawberry notch homolog 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SBNO1
ORF Names:RCJMB04_30k7
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiGallus gallus (Chicken)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9031 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000539 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 15

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003145581 – 1239Protein strawberry notch homolog 1Add BLAST1239

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q5F371

PRoteomics IDEntifications database

More...
PRIDEi
Q5F371

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9031.ENSGALP00000005353

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q5F371

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili838 – 866Sequence analysisAdd BLAST29

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi82 – 127Thr-richAdd BLAST46
Compositional biasi221 – 232Poly-GluAdd BLAST12
Compositional biasi754 – 757Poly-Asp4
Compositional biasi781 – 790Poly-Lys10

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SBNO family.Curated

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1513 Eukaryota
ENOG410XQ7Q LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155449

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000043949

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q5F371

Database of Orthologous Groups

More...
OrthoDBi
141580at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q5F371

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR027417 P-loop_NTPase
IPR026937 SBNO_Helicase_C_dom
IPR026741 SNO
IPR039187 SNO_AAA

The PANTHER Classification System

More...
PANTHERi
PTHR12706 PTHR12706, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13872 AAA_34, 1 hit
PF13871 Helicase_C_4, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q5F371-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVEPGQDLLL AALSESGISP NDLFDIDSPD VVLATPTPAV QQSVPLSALD
60 70 80 90 100
LGLETEAPAA VKQEPETVST PALLNVRQPP STTTFVLNQI NQLPTLGTTI
110 120 130 140 150
VMTKTTPVTT TRQTITVAKI IQTSTTTRPS VAAPAVRNAL TTAPSKDQIQ
160 170 180 190 200
LKDLLKNNSL NELMKLKPPP NIAQPVATAA TDLSNGAVKK EASTKEVARI
210 220 230 240 250
WINDVKMRSF SPTMKVPAVK EEEEPEEEDE EEMGHAETYA EYMPIKLKIG
260 270 280 290 300
LRHPDPVVET SSLSSVTPPD VWYQTSISEE TIDNGWLSAL QLEAITYAAQ
310 320 330 340 350
QHETFLPNGD RAGFLIGDGA GVGKGRTIAG IIYENYLLGR KRAVWFSVSN
360 370 380 390 400
DLKYDAERDL RDIGAKNILV HSLNKFKYGK ISSKHNGSVK KGVIFATYSS
410 420 430 440 450
LIGESQSGGK YKTRLKQLLH WCGEDFDGVI VFDECHKAKN LCPVGSSKPT
460 470 480 490 500
KTGLAVLELQ NKLPKARVVY ASATGASEPR NMAYMNRLGI WGEGTPFREF
510 520 530 540 550
SDFIQAVERR GVGAMEIVAM DMKLRGMYIA RQLSFSGVTF KIDEVLLSQE
560 570 580 590 600
YVKMYNKSVK LWVSARERFQ QAADLIDAEQ RMKKSMWGQF WSAHQRFFKY
610 620 630 640 650
LCIASKVKRV VQLAREEIKN GKCVVIGLQS TGEARTLEAL EEGGGELNDF
660 670 680 690 700
VSTAKGVFQS LIEKHFPAPD RKKLFSLLGI DLTAQSNNNS PRDSPCKENK
710 720 730 740 750
IKKRKGEEVS REAKKARKTG GLAGSSSDES ESESDASDNE ESDNESSRFL
760 770 780 790 800
SSGDDDDFNP FRDESSEDDE DDPWLIRKEH KKVKEKKKKK SIDPDSIQSA
810 820 830 840 850
LLASGLGSKR PSCFTSTVGT TTSSTNASAN SNTNSSFVTS QDAVERAQQM
860 870 880 890 900
KKELLDKLEK LAEDLPPNTL DELIDELGGP ENVAEMTGRK GRVVSNDDGS
910 920 930 940 950
ISYESRSELD VPVEILNITE KQRFMDGDKN IAIISEAASS GISLQADRRA
960 970 980 990 1000
KNQRRRVHMT LELPWSADRA IQQFGRTHRS NQVTAPEYVF LISELAGEQR
1010 1020 1030 1040 1050
FASIVAKRLE SLGALTHGDR RATETRDLSR FNFDNKYGRN ALEIVMKSIV
1060 1070 1080 1090 1100
NLDSPMVSPP PDFPGDFFKD VRQGLIGVGL INVEDRSGIL TLDKDYNNIG
1110 1120 1130 1140 1150
KFLNRILGME VHQQNALFQY FSDTLNAVIQ NAKKNGRYDM GILDLGSGDE
1160 1170 1180 1190 1200
KVRKADVKKF LTPGYSTSGH VELYTISVER GMSWDEATKI WAEQTGPDDG
1210 1220 1230
FYLSLQIRNN KKTAILVKEV NPKKKLFWYT DQILGNNSN
Length:1,239
Mass (Da):137,186
Last modified:March 15, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4FC5C45CD9D2E9D5
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AJ851779 mRNA Translation: CAH65413.1

NCBI Reference Sequences

More...
RefSeqi
NP_001026640.1, NM_001031469.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSGALT00000054517; ENSGALP00000058574; ENSGALG00000003392

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
427694

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
gga:427694

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ851779 mRNA Translation: CAH65413.1
RefSeqiNP_001026640.1, NM_001031469.1

3D structure databases

SMRiQ5F371
ModBaseiSearch...

Protein-protein interaction databases

STRINGi9031.ENSGALP00000005353

Proteomic databases

PaxDbiQ5F371
PRIDEiQ5F371

Genome annotation databases

EnsembliENSGALT00000054517; ENSGALP00000058574; ENSGALG00000003392
GeneIDi427694
KEGGigga:427694

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
55206

Phylogenomic databases

eggNOGiKOG1513 Eukaryota
ENOG410XQ7Q LUCA
GeneTreeiENSGT00940000155449
HOGENOMiHOG000043949
InParanoidiQ5F371
OrthoDBi141580at2759
PhylomeDBiQ5F371

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q5F371

Family and domain databases

InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR026937 SBNO_Helicase_C_dom
IPR026741 SNO
IPR039187 SNO_AAA
PANTHERiPTHR12706 PTHR12706, 1 hit
PfamiView protein in Pfam
PF13872 AAA_34, 1 hit
PF13871 Helicase_C_4, 1 hit
SUPFAMiSSF52540 SSF52540, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSBNO1_CHICK
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5F371
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: March 15, 2005
Last modified: October 16, 2019
This is version 74 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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