Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Type IV inositol polyphosphate 5-phosphatase 11

Gene

IP5P11

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Has phosphatase activity toward PtdIns(4,5)P2, and in vitro toward PtdIns(3,5)P2 and PtdIns(3,4,5)P3. Cannot dephosphorylate PtdIns5P, Ins(1,4,5)P3 and Ins(1,3,4,5)P4.1 Publication

Caution

It is uncertain whether Met-1 or Met-4 is the initiator.Curated

Catalytic activityi

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 4-phosphate + phosphate.2 Publications
1-phosphatidyl-1D-myo-inositol 3,4,5-triphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 3,4-diphosphate + phosphate.1 Publication

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase

Enzyme and pathway databases

BioCyciARA:AT1G47510-MONOMER
ReactomeiR-ATH-1660514 Synthesis of PIPs at the Golgi membrane

Names & Taxonomyi

Protein namesi
Recommended name:
Type IV inositol polyphosphate 5-phosphatase 111 Publication (EC:3.1.3.361 Publication, EC:3.1.3.861 Publication)
Short name:
At5PTase111 Publication
Gene namesi
Name:IP5P11Curated
Ordered Locus Names:At1g47510Imported
ORF Names:F16N3.22Imported
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G47510
TAIRilocus:2015388 AT1G47510

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell membrane, Membrane

Pathology & Biotechi

Disruption phenotypei

Alterations in germination and in dark-growth seedlings. Elevated level of Ins(1,4,5)P3 and InsP2 levels.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002097251 – 334Type IV inositol polyphosphate 5-phosphatase 11Add BLAST334

Proteomic databases

PaxDbiQ5EAF2

Expressioni

Tissue specificityi

Expressed ubiquitously.1 Publication

Inductioni

Induced by abscisic acid (ABA), jasmonic acid (JA) and auxin (PubMed:15181205). Up-regulated in seedlings and down-regulated in mature plant by salt stress (PubMed:21677096).2 Publications

Gene expression databases

ExpressionAtlasiQ5EAF2 baseline and differential

Interactioni

Protein-protein interaction databases

BioGridi26385, 1 interactor
IntActiQ5EAF2, 1 interactor
STRINGi3702.AT1G47510.1

Structurei

3D structure databases

ProteinModelPortaliQ5EAF2
SMRiQ5EAF2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni206 – 222Catalytic 1By similarityAdd BLAST17
Regioni282 – 297Catalytic 2By similarityAdd BLAST16

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG0565 Eukaryota
COG5411 LUCA
HOGENOMiHOG000005663
InParanoidiQ5EAF2
OMAiPEGLWTM
OrthoDBiEOG09360IQI
PhylomeDBiQ5EAF2

Family and domain databases

Gene3Di3.60.10.10, 1 hit
InterProiView protein in InterPro
IPR036691 Endo/exonu/phosph_ase_sf
IPR005135 Endo/exonuclease/phosphatase
IPR000300 IPPc
PfamiView protein in Pfam
PF03372 Exo_endo_phos, 1 hit
SMARTiView protein in SMART
SM00128 IPPc, 1 hit
SUPFAMiSSF56219 SSF56219, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry describes 1 isoform i produced by alternative splicing. AlignAdd to basket
Note: A number of isoforms are produced. According to EST sequences.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q5EAF2-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MPTMGNKNSM CGLKRFPNYK KSPIGSFAKN SSSHDGIKTI EAVNSCSFSR
60 70 80 90 100
KADLCIRIIT WNMNGNVSYE DLVELVGKER KFDLLVVGLQ EAPKANVDQL
110 120 130 140 150
LQTASSPTHE LLGKAKLQSV QLYLFGPKNS HTLVKELKAE RYSVGGCGGL
160 170 180 190 200
IGRKKGAVAI RINYDDIKMV FISCHLSAHA KKVDQRNTEL RHIANSLLPR
210 220 230 240 250
DKRKRDLTVW LGDLNYRIQD VSNHPVRSLI QNHLQSVLVS KDQLLQEAER
260 270 280 290 300
GEIFKGYSEG TLGFKPTYKY NVGSSDYDTS HKIRVPAWTD RILFKIQDTD
310 320 330
NIQATLHSYD SIDQVYGSDH KPVKADLCLK WVNS
Length:334
Mass (Da):37,580
Last modified:March 15, 2005 - v1
Checksum:i73F28B12173C772A
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F4HT96F4HT96_ARATH
Inositol polyphosphate 5-phosphatas...
5PTASE11 AT5PTASE11, At1g47510, F16N3.22, F16N3_22
271Annotation score:
A0A1P8AUV8A0A1P8AUV8_ARATH
Inositol polyphosphate 5-phosphatas...
5PTASE11 AT5PTASE11, At1g47510, F16N3.22, F16N3_22
248Annotation score:
A0A1P8AUX2A0A1P8AUX2_ARATH
Inositol polyphosphate 5-phosphatas...
5PTASE11 AT5PTASE11, At1g47510, F16N3.22, F16N3_22
272Annotation score:

Sequence cautioni

The sequence AAD46036 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007519 Genomic DNA Translation: AAD46036.1 Different initiation.
CP002684 Genomic DNA Translation: AEE32179.1
BT020617 mRNA Translation: AAW81725.1
BT021928 mRNA Translation: AAX49377.1
AY627297 mRNA Translation: AAT45895.1
PIRiD96515
RefSeqiNP_175182.2, NM_103644.3 [Q5EAF2-1]
UniGeneiAt.49311

Genome annotation databases

EnsemblPlantsiAT1G47510.1; AT1G47510.1; AT1G47510 [Q5EAF2-1]
GeneIDi841160
GrameneiAT1G47510.1; AT1G47510.1; AT1G47510 [Q5EAF2-1]
KEGGiath:AT1G47510

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007519 Genomic DNA Translation: AAD46036.1 Different initiation.
CP002684 Genomic DNA Translation: AEE32179.1
BT020617 mRNA Translation: AAW81725.1
BT021928 mRNA Translation: AAX49377.1
AY627297 mRNA Translation: AAT45895.1
PIRiD96515
RefSeqiNP_175182.2, NM_103644.3 [Q5EAF2-1]
UniGeneiAt.49311

3D structure databases

ProteinModelPortaliQ5EAF2
SMRiQ5EAF2
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi26385, 1 interactor
IntActiQ5EAF2, 1 interactor
STRINGi3702.AT1G47510.1

Proteomic databases

PaxDbiQ5EAF2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT1G47510.1; AT1G47510.1; AT1G47510 [Q5EAF2-1]
GeneIDi841160
GrameneiAT1G47510.1; AT1G47510.1; AT1G47510 [Q5EAF2-1]
KEGGiath:AT1G47510

Organism-specific databases

AraportiAT1G47510
TAIRilocus:2015388 AT1G47510

Phylogenomic databases

eggNOGiKOG0565 Eukaryota
COG5411 LUCA
HOGENOMiHOG000005663
InParanoidiQ5EAF2
OMAiPEGLWTM
OrthoDBiEOG09360IQI
PhylomeDBiQ5EAF2

Enzyme and pathway databases

BioCyciARA:AT1G47510-MONOMER
ReactomeiR-ATH-1660514 Synthesis of PIPs at the Golgi membrane

Miscellaneous databases

PROiPR:Q5EAF2

Gene expression databases

ExpressionAtlasiQ5EAF2 baseline and differential

Family and domain databases

Gene3Di3.60.10.10, 1 hit
InterProiView protein in InterPro
IPR036691 Endo/exonu/phosph_ase_sf
IPR005135 Endo/exonuclease/phosphatase
IPR000300 IPPc
PfamiView protein in Pfam
PF03372 Exo_endo_phos, 1 hit
SMARTiView protein in SMART
SM00128 IPPc, 1 hit
SUPFAMiSSF56219 SSF56219, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiIP5PB_ARATH
AccessioniPrimary (citable) accession number: Q5EAF2
Secondary accession number(s): Q9SX81
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 7, 2005
Last sequence update: March 15, 2005
Last modified: April 25, 2018
This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again