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Protein

Cyclin-G1

Gene

CCNG1

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation (By similarity).By similarity

GO - Biological processi

Keywordsi

Molecular functionCyclin
Biological processCell cycle, Cell division, Mitosis

Enzyme and pathway databases

ReactomeiR-BTA-6804757 Regulation of TP53 Degradation

Names & Taxonomyi

Protein namesi
Recommended name:
Cyclin-G1
Gene namesi
Name:CCNG1
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 7

Organism-specific databases

VGNCiVGNC:26969 CCNG1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002823311 – 295Cyclin-G1Add BLAST295

Proteomic databases

PaxDbiQ5E9I1
PRIDEiQ5E9I1

Expressioni

Gene expression databases

BgeeiENSBTAG00000006607

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000008669

Structurei

3D structure databases

ProteinModelPortaliQ5E9I1
SMRiQ5E9I1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cyclin family. Cyclin G subfamily.Curated

Phylogenomic databases

eggNOGiKOG0653 Eukaryota
COG5024 LUCA
GeneTreeiENSGT00530000062971
HOGENOMiHOG000059559
HOVERGENiHBG050839
InParanoidiQ5E9I1
KOiK10145
OMAiSDMMRME
OrthoDBiEOG091G0HQN
TreeFamiTF101007

Family and domain databases

CDDicd00043 CYCLIN, 1 hit
InterProiView protein in InterPro
IPR028860 CCNG1
IPR013763 Cyclin-like
IPR036915 Cyclin-like_sf
IPR006671 Cyclin_N
PANTHERiPTHR10177:SF59 PTHR10177:SF59, 1 hit
PfamiView protein in Pfam
PF00134 Cyclin_N, 1 hit
SMARTiView protein in SMART
SM00385 CYCLIN, 1 hit
SUPFAMiSSF47954 SSF47954, 1 hit

Sequencei

Sequence statusi: Complete.

Q5E9I1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIEVLTTTDS QKLLHQLNAL LEQELRCQPK VCGLRLIESA HDNGLRMTAR
60 70 80 90 100
LRDFEVKDLL SLTQFFGFDT ETFSLAVNLL DRFLSKMKVQ PKHLGCVGLS
110 120 130 140 150
CFYLAVKSTE EERNVPLATD LIRISQYRFT VSDLMRMEKI VLEKVCWKVK
160 170 180 190 200
ATTAFQFLQL YYSLLQENVP HERKSSLNFE RLEAQLKACY CRIIFSKAKP
210 220 230 240 250
SVLALSIIAL EIQAQKYIEL TEGVERLQKH SKISGRDLTF WQELVSKCLA
260 270 280 290
EYSSNKCAKP NVQKLKWIVS GRTARQLRHS YYRITHLPTI PETVP
Length:295
Mass (Da):34,107
Last modified:March 15, 2005 - v1
Checksum:i551AA72198F9224E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT020939 mRNA Translation: AAX08956.1
BT021183 mRNA Translation: AAX31365.1
BC102254 mRNA Translation: AAI02255.1
BC150004 mRNA Translation: AAI50005.1
RefSeqiNP_001013382.1, NM_001013364.1
UniGeneiBt.62415

Genome annotation databases

EnsembliENSBTAT00000008669; ENSBTAP00000008669; ENSBTAG00000006607
GeneIDi281671
KEGGibta:281671

Similar proteinsi

Entry informationi

Entry nameiCCNG1_BOVIN
AccessioniPrimary (citable) accession number: Q5E9I1
Secondary accession number(s): A6QQV2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 3, 2007
Last sequence update: March 15, 2005
Last modified: April 25, 2018
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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