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Protein

tRNA pseudouridine synthase D

Gene

truD

Organism
Aliivibrio fischeri (strain ATCC 700601 / ES114) (Vibrio fischeri)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(13) = tRNA pseudouridine(13).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei81NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processtRNA processing

Enzyme and pathway databases

BioCyciVFIS312309:G1G40-2179-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase DUniRule annotation (EC:5.4.99.27UniRule annotation)
Alternative name(s):
tRNA pseudouridine(13) synthaseUniRule annotation
tRNA pseudouridylate synthase DUniRule annotation
tRNA-uridine isomerase DUniRule annotation
Gene namesi
Name:truDUniRule annotation
Ordered Locus Names:VF_2071
OrganismiAliivibrio fischeri (strain ATCC 700601 / ES114) (Vibrio fischeri)
Taxonomic identifieri312309 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeAliivibrio
Proteomesi
  • UP000000537 Componenti: Chromosome I

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001525261 – 351tRNA pseudouridine synthase DAdd BLAST351

Interactioni

Protein-protein interaction databases

STRINGi312309.VF_2071

Structurei

3D structure databases

ProteinModelPortaliQ5E330
SMRiQ5E330
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini158 – 304TRUDUniRule annotationAdd BLAST147

Sequence similaritiesi

Belongs to the pseudouridine synthase TruD family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4106NZV Bacteria
COG0585 LUCA
HOGENOMiHOG000224848
KOiK06176
OMAiLWLWVEK
OrthoDBiPOG091H03KK

Family and domain databases

HAMAPiMF_01082 TruD, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR001656 PsdUridine_synth_TruD
IPR020119 PsdUridine_synth_TruD_CS
IPR011760 PsdUridine_synth_TruD_insert
PANTHERiPTHR13326 PTHR13326, 2 hits
PfamiView protein in Pfam
PF01142 TruD, 2 hits
SUPFAMiSSF55120 SSF55120, 1 hit
PROSITEiView protein in PROSITE
PS50984 TRUD, 1 hit
PS01268 UPF0024, 1 hit

Sequencei

Sequence statusi: Complete.

Q5E330-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSDIMSNFSW LYGKPVATGK LKQLPEHFIV KEILGFEFTG NGEHLMVKIR
60 70 80 90 100
KTGENTKYVA NELAKFCGVK SKNVSWAGLK DRHAVTEQWL SVQVANSDEL
110 120 130 140 150
NFAKFEATHP GVEILEVTRH NKKLRPGDLQ GNQFQVIATE VTDIDDVLAR
160 170 180 190 200
LEKVKLAGVP NYFGSQRFGH EGNNVNEARR WGRDNVRTRD NSKRSFYLSA
210 220 230 240 250
ARSWIFNHIV SQRITEGYFS QPVDGDILLD RNDRIVNENV TSEESIQKIQ
260 270 280 290 300
NGELSITAAL AGDNQLPTTG TALTLEQPHL DAEPDLMALI RGNRMRHERR
310 320 330 340 350
AIELHPENLT WSAEGDTLTL NFSLTSGSFA TVIVRELLQE IEVERTYSSN

D
Length:351
Mass (Da):39,609
Last modified:March 15, 2005 - v1
Checksum:iA84C37A4A2C98745
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000020 Genomic DNA Translation: AAW86566.1
RefSeqiWP_011262538.1, NC_006840.2
YP_205454.1, NC_006840.2

Genome annotation databases

EnsemblBacteriaiAAW86566; AAW86566; VF_2071
GeneIDi3279153
KEGGivfi:VF_2071
PATRICifig|312309.11.peg.2114

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000020 Genomic DNA Translation: AAW86566.1
RefSeqiWP_011262538.1, NC_006840.2
YP_205454.1, NC_006840.2

3D structure databases

ProteinModelPortaliQ5E330
SMRiQ5E330
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi312309.VF_2071

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAW86566; AAW86566; VF_2071
GeneIDi3279153
KEGGivfi:VF_2071
PATRICifig|312309.11.peg.2114

Phylogenomic databases

eggNOGiENOG4106NZV Bacteria
COG0585 LUCA
HOGENOMiHOG000224848
KOiK06176
OMAiLWLWVEK
OrthoDBiPOG091H03KK

Enzyme and pathway databases

BioCyciVFIS312309:G1G40-2179-MONOMER

Family and domain databases

HAMAPiMF_01082 TruD, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR001656 PsdUridine_synth_TruD
IPR020119 PsdUridine_synth_TruD_CS
IPR011760 PsdUridine_synth_TruD_insert
PANTHERiPTHR13326 PTHR13326, 2 hits
PfamiView protein in Pfam
PF01142 TruD, 2 hits
SUPFAMiSSF55120 SSF55120, 1 hit
PROSITEiView protein in PROSITE
PS50984 TRUD, 1 hit
PS01268 UPF0024, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiTRUD_ALIF1
AccessioniPrimary (citable) accession number: Q5E330
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: March 15, 2005
Last modified: November 7, 2018
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health

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