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Protein

Cancer/testis antigen family 45 member A2

Gene

CT45A2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Cancer/testis antigen family 45 member A2Imported
Alternative name(s):
Cancer/testis antigen 45-21 Publication
Cancer/testis antigen 45A2Curated
Gene namesi
Name:CT45A2Imported
Synonyms:CT45-21 Publication
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

EuPathDBiHostDB:ENSG00000271449.7
HGNCiHGNC:28400 CT45A2
MIMi300793 gene
neXtProtiNX_Q5DJT8

Pathology & Biotechi

Organism-specific databases

DisGeNETi728911
OpenTargetsiENSG00000271449
PharmGKBiPA164718186

Polymorphism and mutation databases

BioMutaiCT45A2
DMDMi160017332

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003089471 – 189Cancer/testis antigen family 45 member A2Add BLAST189

Proteomic databases

EPDiQ5DJT8
PaxDbiQ5DJT8
PeptideAtlasiQ5DJT8
PRIDEiQ5DJT8
ProteomicsDBi62747

PTM databases

iPTMnetiQ5DJT8
PhosphoSitePlusiQ5DJT8

Expressioni

Tissue specificityi

Testis specific. Expressed in cancer cell lines.1 Publication

Gene expression databases

BgeeiENSG00000271449

Organism-specific databases

HPAiHPA044735
HPA044757
HPA046872
HPA046987

Interactioni

Protein-protein interaction databases

IntActiQ5DJT8, 2 interactors
STRINGi9606.ENSP00000359772

Structurei

3D structure databases

ProteinModelPortaliQ5DJT8
SMRiQ5DJT8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CT45 family.

Phylogenomic databases

eggNOGiENOG410JH2S Eukaryota
ENOG41115DR LUCA
GeneTreeiENSGT00390000016655
HOGENOMiHOG000082503
HOVERGENiHBG095520
InParanoidiQ5DJT8
OMAiARYMSGD
OrthoDBiEOG091G0L2U

Family and domain databases

InterProiView protein in InterPro
IPR029307 INT_SG_DDX_CT_C
PfamiView protein in Pfam
PF15300 INT_SG_DDX_CT_C, 1 hit

Sequencei

Sequence statusi: Complete.

Q5DJT8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDKTEKVAV DPETVFKRPR ECDSPSYQKR QRMALLARKQ GAGDSLIAGS
60 70 80 90 100
AMSKEKKLMT GHAIPPSQLD SQIDDFTGFS KDRMMQKPGS NAPVGGNVTS
110 120 130 140 150
SFSGDDLECR ETAFSPKSQQ EINADIKRQL VKELRCVGQK YEKIFEMLEG
160 170 180
VQGPTAVRKR FFESIIKEAA RCMRRDFVKH LKKKLKRMI
Length:189
Mass (Da):21,363
Last modified:May 27, 2015 - v3
Checksum:i2D1A638CBDCF3299
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti57K → E in AAW66465 (PubMed:15905330).Curated1
Sequence conflicti114F → S in AAW66465 (PubMed:15905330).Curated1
Sequence conflicti114F → S in CAI41545 (PubMed:15772651).Curated1
Sequence conflicti129Q → K in AAW66465 (PubMed:15905330).Curated1
Sequence conflicti129Q → K in CAI41545 (PubMed:15772651).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY743710 mRNA Translation: AAW66465.1
AC240441 Genomic DNA No translation available.
AL590618 Genomic DNA Translation: CAI41545.1
CCDSiCCDS76031.1
RefSeqiNP_001278464.1, NM_001291535.1
NP_001278469.1, NM_001291540.2
NP_001308200.1, NM_001321271.1
NP_689795.4, NM_152582.6
XP_006724846.1, XM_006724783.2
XP_006724859.1, XM_006724796.2
XP_006724862.1, XM_006724799.2
XP_011529543.1, XM_011531241.2
XP_011529691.1, XM_011531389.2
UniGeneiHs.535081
Hs.568346
Hs.632281

Genome annotation databases

EnsembliENST00000605791; ENSP00000474632; ENSG00000271449
ENST00000612907; ENSP00000483619; ENSG00000271449
GeneIDi102723680
102723737
728911
KEGGihsa:102723680
hsa:102723737
hsa:728911

Similar proteinsi

Entry informationi

Entry nameiCT452_HUMAN
AccessioniPrimary (citable) accession number: Q5DJT8
Secondary accession number(s): Q5JRH3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: May 27, 2015
Last modified: June 20, 2018
This is version 98 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families

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