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UniProtKB - Q5D0E6 (DALD3_HUMAN)

Entry version 134 (07 Apr 2021)
Sequence version 2 (18 May 2010)
Previous versions | rss
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Protein

DALR anticodon-binding domain-containing protein 3

Gene

DALRD3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in tRNA methylation. Facilitates the recognition and targeting of tRNA(Arg)(CCU) and tRNA(Arg)(UCU) substrates for N3-methylcytidine modification by METTL2A and METTL2B.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • arginine-tRNA ligase activity Source: InterPro
  • ATP binding Source: InterPro
  • tRNA binding Source: UniProtKB
Complete GO annotation on QuickGO ...

GO - Biological processi

  • arginyl-tRNA aminoacylation Source: InterPro
  • tRNA C3-cytosine methylation Source: UniProtKB
Complete GO annotation on QuickGO ...

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q5D0E6

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
DALR anticodon-binding domain-containing protein 3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:DALRD3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:25536, DALRD3

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		618904, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q5D0E6

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000178149.16

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section provides information on the disease(s) associated with genetic variations in a given protein. The information is extracted from the scientific literature and diseases that are also described in the <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=omim">OMIM</a> database are represented with a <a href="http://www.uniprot.org/diseases">controlled vocabulary</a> in the following way:<p><a href='/help/involvement_in_disease' target='_top'>More...</a></p>Involvement in diseasei

Developmental and epileptic encephalopathy 86 (DEE86)1 Publication
The disease may be caused by variants affecting the gene represented in this entry.
Disease descriptionA form of epileptic encephalopathy, a heterogeneous group of severe early-onset epilepsies characterized by refractory seizures, neurodevelopmental impairment, and poor prognosis. Development is normal prior to seizure onset, after which cognitive and motor delays become apparent. DEE86 inheritance is autosomal recessive.
Related information in OMIM
Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_084359417 – 543Missing in DEE86; severe reduction of tRNA(Arg) N(3)-methylcytidine modification. 1 PublicationAdd BLAST127

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Diseasei

Disease variant, Epilepsy

Organism-specific databases

DisGeNET

More...DisGeNETi		55152

MalaCards human disease database

More...MalaCardsi		DALRD3
MIMi618910, phenotype

Open Targets

More...OpenTargetsi		ENSG00000178149

Orphanet; a database dedicated to information on rare diseases and orphan drugs

More...Orphaneti		442835, Undetermined early-onset epileptic encephalopathy

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA134921814

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q5D0E6, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		DALRD3

Domain mapping of disease mutations (DMDM)

More...DMDMi		296434472

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003158481 – 543DALR anticodon-binding domain-containing protein 3Add BLAST543

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q5D0E6

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q5D0E6

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q5D0E6

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q5D0E6

PeptideAtlas

More...PeptideAtlasi		Q5D0E6

PRoteomics IDEntifications database

More...PRIDEi		Q5D0E6

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		62736 [Q5D0E6-1]
62737 [Q5D0E6-2]
62738 [Q5D0E6-3]
62739 [Q5D0E6-4]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q5D0E6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q5D0E6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000178149, Expressed in testis and 219 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q5D0E6, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q5D0E6, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000178149, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Part of a complex containing tRNA(Arg), METTL2A or METTL2B (PubMed:32427860).

Interacts with tRNA(Arg)(CCU) and tRNA(Arg)(UCU) (PubMed:32427860).

Interacts with METTL2A and METTL2B (PubMed:32427860).

1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		120455, 20 interactors

Protein interaction database and analysis system

More...IntActi		Q5D0E6, 16 interactors

Molecular INTeraction database

More...MINTi		Q5D0E6

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000344989

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q5D0E6, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1195, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000014621

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_041286_1_1_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q5D0E6

Identification of Orthologs from Complete Genome Data

More...OMAi		RDPHMLT

Database of Orthologous Groups

More...OrthoDBi		1367114at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q5D0E6

TreeFam database of animal gene trees

More...TreeFami		TF325601

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR008909, DALR_anticod-bd
IPR037380, DALRD3
IPR009080, tRNAsynth_Ia_anticodon-bd

The PANTHER Classification System

More...PANTHERi		PTHR16043, PTHR16043, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF05746, DALR_1, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00836, DALR_1, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF47323, SSF47323, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q5D0E6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MATRRLGVGE TLGALNAALG PGGPVWIKET RTRHLRSRDF LAPHRALQAR 
        60         70         80         90        100
FDDGQVPEHL LHALACLQGP GVAPVLRCAP TPAGLSLQLQ RSAVFERVLS 
       110        120        130        140        150
AVAAYATPAS PASLGQRVLL HCPALRSSPC ALRLSQLRTV LVADHLARAL 
       160        170        180        190        200
RAHGVCVRLV PAVRDPHMLT FLQQLRVDWP AASERASSHT LRSHALEELT 
       210        220        230        240        250
SANDGRTLSP GILGRLCLKE LVEEQGRTAG YDPNLDNCLV TEDLLSVLAE 
       260        270        280        290        300
LQEALWHWPE DSHPGLAGAS DTGTGGCLVV HVVSCEEEFQ QQKLDLLWQK 
       310        320        330        340        350
LVDKAPLRQK HLICGPVKVA GAPGTLMTAP EYYEFRHTQV CKASALKHGG 
       360        370        380        390        400
DLAQDPAWTE IFGVLSVATI KFEMLSTAPQ SQLFLALADS SISTKGTKSG 
       410        420        430        440        450
TFVMYNCARL ATLFESYKCS MEQGLYPTFP PVSSLDFSLL HDEGEWLLLF 
       460        470        480        490        500
NSILPFPDLL SRTAVLDCTA PGLHIAVRTE MICKFLVQLS MDFSSYYNRV 
       510        520        530        540 
HILGEPRPHL FGQMFVRLQL LRAVREVLHT GLAMLGLPPL SHI
Length:543
Mass (Da):59,363
Last modified:May 18, 2010 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i78AFBA859D0E074B
GO
Isoform 2 (identifier: Q5D0E6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     444-543: GEWLLLFNSI...MLGLPPLSHI → YPPLSGSAEP...RPPAASESCA

Show »
Length:516
Mass (Da):55,453
Checksum:iBB3C375E2DB6196C
GO
Isoform 3 (identifier: Q5D0E6-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     133-138: RLSQLR → TGCACA
     139-543: Missing.

Show »
Length:138
Mass (Da):14,419
Checksum:iB6E76E24E397A7E9
GO
Isoform 4 (identifier: Q5D0E6-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-167: Missing.

Show »
Length:376
Mass (Da):41,590
Checksum:iF0812124BD2BC042
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H7C0T8H7C0T8_HUMAN
DALR anticodon-binding domain-conta...
DALRD3
184Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JA38C9JA38_HUMAN
DALR anticodon-binding domain-conta...
DALRD3
293Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JJG6C9JJG6_HUMAN
DALR anticodon-binding domain-conta...
DALRD3
386Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A096LNZ3A0A096LNZ3_HUMAN
DALR anticodon-binding domain-conta...
DALRD3
72Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti27I → T in BAA91647 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_038349299Q → R2 PublicationsCorresponds to variant dbSNP:rs3087866Ensembl.1
Natural variantiVAR_084359417 – 543Missing in DEE86; severe reduction of tRNA(Arg) N(3)-methylcytidine modification. 1 PublicationAdd BLAST127

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0307411 – 167Missing in isoform 4. 1 PublicationAdd BLAST167
Alternative sequenceiVSP_030743133 – 138RLSQLR → TGCACA in isoform 3. 1 Publication6
Alternative sequenceiVSP_030744139 – 543Missing in isoform 3. 1 PublicationAdd BLAST405
Alternative sequenceiVSP_030746444 – 543GEWLL…PLSHI → YPPLSGSAEPDSSAGLHSPG APHCCTHRDDMQVPGTAQHG FQLLLQPGTHPGGASTTPLW SDVRPPAASESCA in isoform 2. 1 PublicationAdd BLAST100

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AK001358 mRNA Translation: BAA91647.1
AK093204 mRNA Translation: BAC04095.1
AK093294 mRNA Translation: BAC04123.1
AC137630 Genomic DNA No translation available.
BC032440 mRNA Translation: AAH32440.2
BC047683 mRNA Translation: AAH47683.1
BC054493 mRNA Translation: AAH54493.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS2783.1 [Q5D0E6-4]
CCDS33754.1 [Q5D0E6-1]
CCDS63632.1 [Q5D0E6-2]

NCBI Reference Sequences

More...RefSeqi		NP_001009996.1, NM_001009996.2 [Q5D0E6-1]
NP_001263334.1, NM_001276405.1 [Q5D0E6-2]
NP_060584.3, NM_018114.5 [Q5D0E6-4]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000313778; ENSP00000323265; ENSG00000178149 [Q5D0E6-4]
ENST00000341949; ENSP00000344989; ENSG00000178149 [Q5D0E6-1]
ENST00000441576; ENSP00000410623; ENSG00000178149 [Q5D0E6-2]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		55152

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:55152

UCSC genome browser

More...UCSCi		uc003cvk.4, human [Q5D0E6-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK001358 mRNA Translation: BAA91647.1
AK093204 mRNA Translation: BAC04095.1
AK093294 mRNA Translation: BAC04123.1
AC137630 Genomic DNA No translation available.
BC032440 mRNA Translation: AAH32440.2
BC047683 mRNA Translation: AAH47683.1
BC054493 mRNA Translation: AAH54493.1
CCDSiCCDS2783.1 [Q5D0E6-4]
CCDS33754.1 [Q5D0E6-1]
CCDS63632.1 [Q5D0E6-2]
RefSeqiNP_001009996.1, NM_001009996.2 [Q5D0E6-1]
NP_001263334.1, NM_001276405.1 [Q5D0E6-2]
NP_060584.3, NM_018114.5 [Q5D0E6-4]

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi120455, 20 interactors
IntActiQ5D0E6, 16 interactors
MINTiQ5D0E6
STRINGi9606.ENSP00000344989

PTM databases

iPTMnetiQ5D0E6
PhosphoSitePlusiQ5D0E6

Genetic variation databases

BioMutaiDALRD3
DMDMi296434472

Proteomic databases

jPOSTiQ5D0E6
MassIVEiQ5D0E6
MaxQBiQ5D0E6
PaxDbiQ5D0E6
PeptideAtlasiQ5D0E6
PRIDEiQ5D0E6
ProteomicsDBi62736 [Q5D0E6-1]
62737 [Q5D0E6-2]
62738 [Q5D0E6-3]
62739 [Q5D0E6-4]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		30345, 104 antibodies

The DNASU plasmid repository

More...DNASUi		55152

Genome annotation databases

EnsembliENST00000313778; ENSP00000323265; ENSG00000178149 [Q5D0E6-4]
ENST00000341949; ENSP00000344989; ENSG00000178149 [Q5D0E6-1]
ENST00000441576; ENSP00000410623; ENSG00000178149 [Q5D0E6-2]
GeneIDi55152
KEGGihsa:55152
UCSCiuc003cvk.4, human [Q5D0E6-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		55152
DisGeNETi55152

GeneCards: human genes, protein and diseases

More...GeneCardsi		DALRD3
HGNCiHGNC:25536, DALRD3
HPAiENSG00000178149, Low tissue specificity
MalaCardsiDALRD3
MIMi618904, gene
618910, phenotype
neXtProtiNX_Q5D0E6
OpenTargetsiENSG00000178149
Orphaneti442835, Undetermined early-onset epileptic encephalopathy
PharmGKBiPA134921814
VEuPathDBiHostDB:ENSG00000178149.16

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG1195, Eukaryota
GeneTreeiENSGT00390000014621
HOGENOMiCLU_041286_1_1_1
InParanoidiQ5D0E6
OMAiRDPHMLT
OrthoDBi1367114at2759
PhylomeDBiQ5D0E6
TreeFamiTF325601

Enzyme and pathway databases

PathwayCommonsiQ5D0E6

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		55152, 13 hits in 993 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		DALRD3, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		55152
PharosiQ5D0E6, Tdark

Protein Ontology

More...PROi		PR:Q5D0E6
RNActiQ5D0E6, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000178149, Expressed in testis and 219 other tissues
ExpressionAtlasiQ5D0E6, baseline and differential
GenevisibleiQ5D0E6, HS

Family and domain databases

InterProiView protein in InterPro
IPR008909, DALR_anticod-bd
IPR037380, DALRD3
IPR009080, tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR16043, PTHR16043, 1 hit
PfamiView protein in Pfam
PF05746, DALR_1, 1 hit
SMARTiView protein in SMART
SM00836, DALR_1, 1 hit
SUPFAMiSSF47323, SSF47323, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiDALD3_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5D0E6
Secondary accession number(s): Q7Z5S7
, Q86WY1, Q8N105, Q8NA89, Q9NVU8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: May 18, 2010
Last modified: April 7, 2021
This is version 134 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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