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UniProtKB - Q5CRJ8 (Q5CRJ8_CRYPI)
Protein
Submitted name:
Cdc2-like CDK2/CDC28 like protein kinase
Gene
cgd5_2510
Organism
Cryptosporidium parvum (strain Iowa II)
Status
Functioni
Caution
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 33 | ADPCombined sources | 1 | |
Binding sitei | 33 | ATPPROSITE-ProRule annotation | 1 | |
Binding sitei | 144 | ADPCombined sources | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 81 – 86 | ADPCombined sources | 6 | |
Nucleotide bindingi | 130 – 131 | ADPCombined sources | 2 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-UniRule
- protein serine/threonine kinase activity Source: UniProtKB-KW
Keywordsi
Molecular function | Kinase, Serine/threonine-protein kinaseUniRule annotation, Transferase |
Ligand | ATP-bindingPROSITE-ProRule annotationARBA annotation, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Submitted name: Cdc2-like CDK2/CDC28 like protein kinaseImported |
Gene namesi | ORF Names:cgd5_2510Imported |
Organismi | Cryptosporidium parvum (strain Iowa II)Imported |
Taxonomic identifieri | 353152 [NCBI] |
Taxonomic lineagei | Eukaryota › Sar › Alveolata › Apicomplexa › Conoidasida › Coccidia › Eucoccidiorida › Eimeriorina › Cryptosporidiidae › Cryptosporidium › |
Proteomesi |
|
Structurei
3D structure databases
SMRi | Q5CRJ8 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | Q5CRJ8 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 5 – 286 | Protein kinaseInterPro annotationAdd BLAST | 282 |
Sequence similaritiesi
Belongs to the protein kinase superfamily.UniRule annotation
Phylogenomic databases
InParanoidi | Q5CRJ8 |
OMAi | NYTHEIV |
Family and domain databases
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR000719, Prot_kinase_dom IPR017441, Protein_kinase_ATP_BS IPR008271, Ser/Thr_kinase_AS |
Pfami | View protein in Pfam PF00069, Pkinase, 1 hit |
SMARTi | View protein in SMART SM00220, S_TKc, 1 hit |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS00107, PROTEIN_KINASE_ATP, 1 hit PS50011, PROTEIN_KINASE_DOM, 1 hit PS00108, PROTEIN_KINASE_ST, 1 hit |
i Sequence
Sequence statusi: Fragment.
Q5CRJ8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
LMEKYQKLEK VGEGTYGVVY KAKDSQGRIV ALKRIRLDAE DEGIPSTAIR
60 70 80 90 100
EISLLKELHH PNIVSLIDVI HSERCLTLVF EFMEKDLKKV LDENKTGLQD
110 120 130 140 150
SQIKIYLYQL LRGVAHCHQH RILHRDLKPQ NLLINSDGAL KLADFGLARA
160 170 180 190 200
FGIPVRSYTH EVVTLWYRAP DVLMGSKKYS TSVDIWSIGC IFAEMITGKP
210 220 230 240 250
LFPGVTDDDQ LPKIFSILGT PNPREWPQVQ ELPLWKQRTF QVFEKKPWSS
260 270 280 290
IIPGFCQEGI DLLSNMLCFD PNKRISARDA MNHPYFKDLD PQIMI
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAEE01000007 Genomic DNA Translation: EAK88218.1 |
RefSeqi | XP_626188.1, XM_626188.1 |
Genome annotation databases
EnsemblProtistsi | EAK88218; EAK88218; cgd5_2510 |
GeneIDi | 3373206 |
KEGGi | cpv:cgd5_2510 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAEE01000007 Genomic DNA Translation: EAK88218.1 |
RefSeqi | XP_626188.1, XM_626188.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
2QKR | X-ray | 2.60 | A | 1-295 | [»] | |
3NIZ | X-ray | 2.40 | A | 1-293 | [»] | |
SMRi | Q5CRJ8 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
STRINGi | 353152.Q5CRJ8 |
Genome annotation databases
EnsemblProtistsi | EAK88218; EAK88218; cgd5_2510 |
GeneIDi | 3373206 |
KEGGi | cpv:cgd5_2510 |
Phylogenomic databases
InParanoidi | Q5CRJ8 |
OMAi | NYTHEIV |
Miscellaneous databases
EvolutionaryTracei | Q5CRJ8 |
Family and domain databases
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR000719, Prot_kinase_dom IPR017441, Protein_kinase_ATP_BS IPR008271, Ser/Thr_kinase_AS |
Pfami | View protein in Pfam PF00069, Pkinase, 1 hit |
SMARTi | View protein in SMART SM00220, S_TKc, 1 hit |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS00107, PROTEIN_KINASE_ATP, 1 hit PS50011, PROTEIN_KINASE_DOM, 1 hit PS00108, PROTEIN_KINASE_ST, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Q5CRJ8_CRYPI | |
Accessioni | Q5CRJ8Primary (citable) accession number: Q5CRJ8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 12, 2005 |
Last sequence update: | April 12, 2005 | |
Last modified: | January 19, 2022 | |
This is version 102 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |