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UniProtKB - Q5C9Z4 (NOM1_HUMAN)

Entry version 132 (23 Feb 2022)
Sequence version 1 (12 Apr 2005)
Previous versions | rss
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Protein

Nucleolar MIF4G domain-containing protein 1

Gene

NOM1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Plays a role in targeting PPP1CA to the nucleolus.

1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q5C9Z4

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		Q5C9Z4

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Nucleolar MIF4G domain-containing protein 1
Alternative name(s):
SGD1 homolog
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:NOM1
Synonyms:C7orf3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:13244, NOM1

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		611269, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q5C9Z4

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000146909

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi308V → A: Loss of interaction with PPP1CA and loss of ability to relocalize PPP1CA to the nucleolus; when associated with A-310. 1 Publication1
Mutagenesisi310F → A: Loss of interaction with PPP1CA and loss of ability to relocalize PPP1CA to the nucleolus; when associated with A-308. 1 Publication1

Organism-specific databases

DisGeNET

More...DisGeNETi		64434

Open Targets

More...OpenTargetsi		ENSG00000146909

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA25946

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q5C9Z4, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		NOM1

Domain mapping of disease mutations (DMDM)

More...DMDMi		74707675

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002868231 – 860Nucleolar MIF4G domain-containing protein 1Add BLAST860

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei57PhosphoserineCombined sources1
Modified residuei139PhosphoserineCombined sources1
Modified residuei317PhosphoserineCombined sources1
Modified residuei320PhosphoserineCombined sources1
Modified residuei321PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q5C9Z4

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q5C9Z4

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q5C9Z4

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q5C9Z4

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q5C9Z4

PeptideAtlas

More...PeptideAtlasi		Q5C9Z4

PRoteomics IDEntifications database

More...PRIDEi		Q5C9Z4

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		62725

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...GlyGeni		Q5C9Z4, 1 site, 1 O-linked glycan (1 site)

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q5C9Z4

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q5C9Z4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in heart and skeletal muscle.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000146909, Expressed in epithelial cell of pancreas and 210 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q5C9Z4, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000146909, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

May interact with EIF4A1, EIF4A2 and EIF4A3.

Interacts with PPP1CA and PPP1CC.

1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		122182, 103 interactors

The Eukaryotic Linear Motif resource for Functional Sites in Proteins

More...ELMi		Q5C9Z4

Protein interaction database and analysis system

More...IntActi		Q5C9Z4, 50 interactors

Molecular INTeraction database

More...MINTi		Q5C9Z4

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000275820

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q5C9Z4, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q5C9Z4

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini362 – 559MIF4GPROSITE-ProRule annotationAdd BLAST198
Domaini654 – 770MIPROSITE-ProRule annotationAdd BLAST117

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 269Necessary for nucleolar localization and for targeting PPP1CA to the nucleolusAdd BLAST269
Regioni1 – 172DisorderedSequence analysisAdd BLAST172
Regioni191 – 211DisorderedSequence analysisAdd BLAST21
Regioni225 – 339DisorderedSequence analysisAdd BLAST115

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi307 – 310Required for efficient binding to PPP1CA and for targeting PPP1CA to the nucleolus4

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi37 – 53Basic and acidic residuesSequence analysisAdd BLAST17
Compositional biasi80 – 97Basic residuesSequence analysisAdd BLAST18
Compositional biasi118 – 144Basic and acidic residuesSequence analysisAdd BLAST27
Compositional biasi235 – 265Acidic residuesSequence analysisAdd BLAST31
Compositional biasi293 – 316Basic and acidic residuesSequence analysisAdd BLAST24

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the CWC22 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG2141, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000153458

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_006786_0_1_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q5C9Z4

Identification of Orthologs from Complete Genome Data

More...OMAi		LRICRMA

Database of Orthologous Groups

More...OrthoDBi		307186at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q5C9Z4

TreeFam database of animal gene trees

More...TreeFami		TF312808

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR016024, ARM-type_fold
IPR003891, Initiation_fac_eIF4g_MI
IPR003890, MIF4G-like_typ-3

Pfam protein domain database

More...Pfami		View protein in Pfam
PF02847, MA3, 1 hit
PF02854, MIF4G, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00544, MA3, 1 hit
SM00543, MIF4G, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF48371, SSF48371, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51366, MI, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q5C9Z4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAASRSAGEA GPGGSQGRVV RMKRRGGRGP RRGPAGGGEK ALKRLKLAVE 
        60         70         80         90        100
EFVHATSEGE APGGCEGRGA PVSFRPGGRK SRKELRKEKR HLRKARRLQR 
       110        120        130        140        150
TAGPEQGPGL GGRSGAEEAS GHRQDTEERA RPAPSRDPSP PRKPRPSRVK 
       160        170        180        190        200
AKATAATAKT RPSAAATAAA RKRALLAANE EEDREIRKLE RCLGLNKRKK 
       210        220        230        240        250
KDGSSSVPLS FARDGLDYIL GALESGKNSG LYDSSGEEEE DAGQTLPESD 
       260        270        280        290        300
LESDSQDESE EEEEGDVEKE KKAQEAEAQS EDDDEDTEEE QGEEKEKGAQ 
       310        320        330        340        350
EKRRGKRVRF AEDEEKSENS SEDGDITDKS LCGSGEKYIP PHVRQAEETV 
       360        370        380        390        400
DFKKKEELER LKKHVKGLLN RLSEPNMASI SGQLEELYMA HSRKDMNDTL 
       410        420        430        440        450
TSALMGACVT ASAMPSRLMM EHVLLVSILH HTVGIEVGAH FLEAVVRKFD 
       460        470        480        490        500
AIYKYGSEGK ECDNLFTVIA HLYNFHVVQS LLIFDILKKL IGTFTEKDIE 
       510        520        530        540        550
LILLMLKNVG FSLRKDDALS LKELITEAQT KASGAGSEFQ DQTRIRFMLE 
       560        570        580        590        600
TMLALKNNDM RKIPGYDPEP VEKLRKLQRA LVRNAGSGSE TQLRVSWDSV 
       610        620        630        640        650
LSAEQTGRWW IVGSAWSGAP MIDNSHHTHL QKQLVGTVSS KILELARKQR 
       660        670        680        690        700
MNTDIRRNIF CTIMTSEDFL DAFEKLLKLG LKDQQEREII HVLMDCCLQE 
       710        720        730        740        750
KTYNPFYAFL ASKFCEYERR FQMTFQFSIW DKFRDLENLP ATNFSNLVHL 
       760        770        780        790        800
VAHLLKTKSL SLSILKVVEF SELDKPRVRF LRKVLSILLM ETEVEDLSLI 
       810        820        830        840        850
FTRVSDNPKL GVLREGLKLF ISHFLLKNAQ AHRSADEANV LREKADLATK 
       860
CLQGKASLRM
Length:860
Mass (Da):96,257
Last modified:April 12, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD4FAB8FB9AC3B5C9
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_06199924R → G. Corresponds to variant dbSNP:rs6969990Ensembl.1
Natural variantiVAR_032187122H → P. Corresponds to variant dbSNP:rs6952214Ensembl.1
Natural variantiVAR_053051723M → V. Corresponds to variant dbSNP:rs12919Ensembl.1
Natural variantiVAR_032188779R → H. Corresponds to variant dbSNP:rs2302445Ensembl.1
Natural variantiVAR_032189804V → L. Corresponds to variant dbSNP:rs2302443Ensembl.1
Natural variantiVAR_032190812V → M. Corresponds to variant dbSNP:rs12919Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AY576779 mRNA Translation: AAT39521.1
AF107455 mRNA No translation available.
BC007902 mRNA Translation: AAH07902.2

The Consensus CDS (CCDS) project

More...CCDSi		CCDS34787.1

NCBI Reference Sequences

More...RefSeqi		NP_612409.1, NM_138400.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000275820; ENSP00000275820; ENSG00000146909

Database of genes from NCBI RefSeq genomes

More...GeneIDi		64434

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:64434

Matched Annotation from NCBI and EMBL-EBI (MANE) - Phase one

More...MANE-Selecti		ENST00000275820.4; ENSP00000275820.3; NM_138400.2; NP_612409.1

UCSC genome browser

More...UCSCi		uc003wmy.3, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY576779 mRNA Translation: AAT39521.1
AF107455 mRNA No translation available.
BC007902 mRNA Translation: AAH07902.2
CCDSiCCDS34787.1
RefSeqiNP_612409.1, NM_138400.1

3D structure databases

SMRiQ5C9Z4
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi122182, 103 interactors
ELMiQ5C9Z4
IntActiQ5C9Z4, 50 interactors
MINTiQ5C9Z4
STRINGi9606.ENSP00000275820

PTM databases

GlyGeniQ5C9Z4, 1 site, 1 O-linked glycan (1 site)
iPTMnetiQ5C9Z4
PhosphoSitePlusiQ5C9Z4

Genetic variation databases

BioMutaiNOM1
DMDMi74707675

Proteomic databases

EPDiQ5C9Z4
jPOSTiQ5C9Z4
MassIVEiQ5C9Z4
MaxQBiQ5C9Z4
PaxDbiQ5C9Z4
PeptideAtlasiQ5C9Z4
PRIDEiQ5C9Z4
ProteomicsDBi62725

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		56748, 65 antibodies from 18 providers

The DNASU plasmid repository

More...DNASUi		64434

Genome annotation databases

EnsembliENST00000275820; ENSP00000275820; ENSG00000146909
GeneIDi64434
KEGGihsa:64434
MANE-SelectiENST00000275820.4; ENSP00000275820.3; NM_138400.2; NP_612409.1
UCSCiuc003wmy.3, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		64434
DisGeNETi64434

GeneCards: human genes, protein and diseases

More...GeneCardsi		NOM1
HGNCiHGNC:13244, NOM1
HPAiENSG00000146909, Low tissue specificity
MIMi611269, gene
neXtProtiNX_Q5C9Z4
OpenTargetsiENSG00000146909
PharmGKBiPA25946
VEuPathDBiHostDB:ENSG00000146909

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG2141, Eukaryota
GeneTreeiENSGT00940000153458
HOGENOMiCLU_006786_0_1_1
InParanoidiQ5C9Z4
OMAiLRICRMA
OrthoDBi307186at2759
PhylomeDBiQ5C9Z4
TreeFamiTF312808

Enzyme and pathway databases

PathwayCommonsiQ5C9Z4
SignaLinkiQ5C9Z4

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		64434, 604 hits in 1057 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		NOM1, human

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		NOM1

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		64434
PharosiQ5C9Z4, Tbio

Protein Ontology

More...PROi		PR:Q5C9Z4
RNActiQ5C9Z4, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000146909, Expressed in epithelial cell of pancreas and 210 other tissues
GenevisibleiQ5C9Z4, HS

Family and domain databases

InterProiView protein in InterPro
IPR016024, ARM-type_fold
IPR003891, Initiation_fac_eIF4g_MI
IPR003890, MIF4G-like_typ-3
PfamiView protein in Pfam
PF02847, MA3, 1 hit
PF02854, MIF4G, 1 hit
SMARTiView protein in SMART
SM00544, MA3, 1 hit
SM00543, MIF4G, 1 hit
SUPFAMiSSF48371, SSF48371, 1 hit
PROSITEiView protein in PROSITE
PS51366, MI, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNOM1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5C9Z4
Secondary accession number(s): Q96I08
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: April 12, 2005
Last modified: February 23, 2022
This is version 132 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
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