Cux1

Functionⁱ

Regions

Feature key	Position(s)	DescriptionActions	Graphical view	Length
DNA bindingⁱ	1150 – 1209	HomeoboxPROSITE-ProRule annotationAdd BLAST		60

GO - Molecular functionⁱ

sequence-specific DNA binding Source: InterPro

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

regulation of transcription, DNA-templated Source: UniProtKB-KW
transcription, DNA-templated Source: UniProtKB-KW

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	DNA-bindingPROSITE-ProRule annotationImported
Biological process	Transcription, Transcription regulationUniRule annotation

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Homeobox protein cut-likeUniRule annotation
Gene namesⁱ	Name:Cux1Imported Synonyms:Cutl1Imported
Organismⁱ	Mus musculus (Mouse)Imported
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus

Organism-specific databases

MGIⁱ	MGI:88568 Cux1

Keywords - Cellular componentⁱ

NucleusPROSITE-ProRule annotation

PTM / Processingⁱ

Proteomic databases

PeptideAtlas More...PeptideAtlasⁱ	Q5BL05

PeptideAtlasⁱ

Q5BL05

Expressionⁱ

Gene expression databases

Genevisibleⁱ	Q5BL05 MM

Genevisibleⁱ

Q5BL05 MM

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q5BL05
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Domainⁱ	451 – 538	CUTInterPro annotationAdd BLAST	88
Domainⁱ	840 – 927	CUTInterPro annotationAdd BLAST	88
Domainⁱ	1023 – 1110	CUTInterPro annotationAdd BLAST	88
Domainⁱ	1148 – 1208	HomeoboxInterPro annotationAdd BLAST	61

Coiled coil

Feature key	Position(s)	DescriptionActions	Length
Coiled coilⁱ	17 – 37	Sequence analysisAdd BLAST	21
Coiled coilⁱ	68 – 88	Sequence analysisAdd BLAST	21
Coiled coilⁱ	112 – 196	Sequence analysisAdd BLAST	85
Coiled coilⁱ	201 – 228	Sequence analysisAdd BLAST	28
Coiled coilⁱ	237 – 274	Sequence analysisAdd BLAST	38
Coiled coilⁱ	296 – 355	Sequence analysisAdd BLAST	60

Sequence similaritiesⁱ

Belongs to the CUT homeobox family.UniRule annotation

Keywords - Domainⁱ

Coiled coilSequence analysis, HomeoboxPROSITE-ProRule annotationImported

Phylogenomic databases

eggNOGⁱ	KOG0963 Eukaryota KOG2252 Eukaryota ENOG410XPRP LUCA
HOVERGENⁱ	HBG051268
KEGG Orthology (KO) More...KOⁱ	K09313

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00086 homeodomain, 1 hit
InterProⁱ	View protein in InterPro IPR003350 CUT_dom IPR009057 Homeobox-like_sf IPR017970 Homeobox_CS IPR001356 Homeobox_dom IPR010982 Lambda_DNA-bd_dom_sf
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF02376 CUT, 3 hits PF00046 Homeobox, 1 hit
SMARTⁱ	View protein in SMART SM01109 CUT, 3 hits SM00389 HOX, 1 hit
SUPFAMⁱ	SSF46689 SSF46689, 1 hit SSF47413 SSF47413, 3 hits
PROSITEⁱ	View protein in PROSITE PS51042 CUT, 3 hits PS00027 HOMEOBOX_1, 1 hit PS50071 HOMEOBOX_2, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

Q5BL05-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MAANVGSMFQ YWKRFDLQQL QRELDATATV LANRQDESEQ SRKRLIEQSR 
        60         70         80         90        100
EFKKNTPEDL RKQVAPLLKS FQGEIDALSK RSKEAEAAFL TVYKRLIDVP 
       110        120        130        140        150
DPVPALDVGQ QLEIKVQRLH DIETENQKLR ETLEEYNKEF AEVKNQEVTI 
       160        170        180        190        200
KALKEKIREY EQTLKSQAET IALEKEQKLQ NDFAEKERKL QETQMSTTSK 
       210        220        230        240        250
LEEAEHKLQT LQTALEKTRT ELFDLKTKYD EETTAKADEI EMIMTDLERA 
       260        270        280        290        300
NQRAEVAQRE AETLREQLSS ANHSLQLASQ IQKAPDVEQA IEVLTRSSLE 
       310        320        330        340        350
VELAAKEREI AQLVEDVQRL QASLTKLREN SASQISQLEQ QLNAKNSTLK 
       360        370        380        390        400
QLEEKLKGQA DYEEVKKELN TLKSMEFAPS EGAGTQDSTK PLEVLLLEKN 
       410        420        430        440        450
RSLQSENATL RISNSDLSGP YSTNSISSPS PLQQSPDVNG MAPSPSQSES 
       460        470        480        490        500
AGSISEGEEI DTAEIARQVK EQLIKHNIGQ RIFGHYVLGL SQGSVSEILA 
       510        520        530        540        550
RPKPWNKLTV RGKEPFHKMK QFLSDEQNIL ALRSIQGRQR ENPGQSLNRL 
       560        570        580        590        600
FQEVPKRRNG SEGNITTRIR ASETGSDEAI KSILEQAKRE LQVQKTAEPV 
       610        620        630        640        650
QTSSTSSSGN SDDAIRSILQ QARREMEAQQ AALDPALKPA PLSQPDLTIL 
       660        670        680        690        700
TPKHLSASPM STVSTYPPLA ISLKKTPAAP ETSTAALPSA PALKKEAQDV 
       710        720        730        740        750
PTLDPPGSAD AAQGVLRPMK SELVRGSTWK DPWWSPIQPE RRNLTSSEET 
       760        770        780        790        800
KADETTASGK ERAGSSQPRA ERSQLQGPSA SAEYWKEWPS AESPYSQSSE 
       810        820        830        840        850
LSLTGASRSE TPQNSPLPSS PIVPMAKPAK PSVPPLTPEQ YEVYMYQEVD 
       860        870        880        890        900
TIELTRQVKE KLAKNGICQR IFGEKVLGLS QGSVSDMLSR PKPWSKLTQK 
       910        920        930        940        950
GREPFIRMQL WLNGELGQGV LPVQGQQQGP VLHSVASLQD PLQQGCVSSE 
       960        970        980        990       1000
STPKTSASCS PAPESPMSSS ESVKSLTELV QQPCPAIETS KEGKPPEPSD 
      1010       1020       1030       1040       1050
PPASDSQPTT PLPLSGHSAL SIQELVAMSP ELDTYGITKR VKEVLTDNNL 
      1060       1070       1080       1090       1100
GQRLFGETIL GLTQGSVSDL LARPKPWHKL SLKGREPFVR MQLWLNDPNN 
      1110       1120       1130       1140       1150
VEKLMDMKRM EKKAYMKRRH SSVSDSQPCE PPSVGIDYSQ GASPHPQHQL 
      1160       1170       1180       1190       1200
KKPRVVLAPE EKEALKRAYQ QKPYPSPKTI EELATQLNLK TSTVINWFHN 
      1210       1220       1230       1240       1250
YRSRIRRELF IEEIQAGSQG QAGASDSPSA RSSRAAPSSE GDSCDGVEAT 
      1260       1270       1280       1290       1300
DAEEPGGNIV ATKSQGGLAE VAAAPADREE ATQPAEKAKA QPLCSGTPGQ 
      1310       1320       1330       1340       1350
DDGEDASRPR PLPEGLADAP APVPSLAAPA AGEDAATSAT APATATEAPG 
      1360       1370       1380       1390       1400
AARAGPAERS SALPSTSAPA NAPARRPSSL QSLFGLPEAA GARDNLVRKK 
      1410       1420 
KAANLNSIIH RLEKAASREE PIEWEF

Length:1,426

Mass (Da):156,408

Last modified:April 12, 2005 - v1

Checksum:ⁱ373175EE0CD6001F

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BC090847 mRNA Translation: AAH90847.1
NCBI Reference Sequences More...RefSeqⁱ	NP_001278162.1, NM_001291233.1 NP_001278163.1, NM_001291234.1 NP_001278167.1, NM_001291238.1 NP_034116.3, NM_009986.4 NP_941004.2, NM_198602.3
UniGeneⁱ	Mm.320317 Mm.436792

Genome annotation databases

GeneIDⁱ	13047
KEGGⁱ	mmu:13047

Similar proteinsⁱ

90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q5BL05	Isoform 2 of Homeobox protein cut-like 1		MOUSE		1413	UniRef90_P53564-2
UPI0000DA3836		RAT		1511
UPI000A305FAB		MUSPA		1421
UPI000A315F04		MUSCR		1416
UPI000B4F2B37		MERUN		1416
+5

Protein	Similar proteins		Species	Score	Length	Source
Q5BL05	Homeobox protein cut-like 1		MOUSE		1515	UniRef50_P53564
Homeobox protein cut-like 1		HUMAN		1505
Homeobox protein cut-like 1		RAT		1504
Homeobox protein cut-like		DELLE		1627
Homeobox protein cut-like		Enhydra lutris kenyoni		1552
+451

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BC090847 mRNA Translation: AAH90847.1
RefSeqⁱ	NP_001278162.1, NM_001291233.1 NP_001278163.1, NM_001291234.1 NP_001278167.1, NM_001291238.1 NP_034116.3, NM_009986.4 NP_941004.2, NM_198602.3
UniGeneⁱ	Mm.320317 Mm.436792

3D structure databases

ProteinModelPortalⁱ	Q5BL05
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Proteomic databases

PeptideAtlasⁱ	Q5BL05

PeptideAtlasⁱ

Q5BL05

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

GeneIDⁱ	13047
KEGGⁱ	mmu:13047

Organism-specific databases

CTDⁱ	1523
MGIⁱ	MGI:88568 Cux1

Phylogenomic databases

eggNOGⁱ	KOG0963 Eukaryota KOG2252 Eukaryota ENOG410XPRP LUCA
HOVERGENⁱ	HBG051268
KOⁱ	K09313

Miscellaneous databases

ChiTaRSⁱ	Cux1 mouse
SOURCEⁱ	Search...

Gene expression databases

Genevisibleⁱ	Q5BL05 MM

Genevisibleⁱ

Q5BL05 MM

Family and domain databases

CDDⁱ	cd00086 homeodomain, 1 hit
InterProⁱ	View protein in InterPro IPR003350 CUT_dom IPR009057 Homeobox-like_sf IPR017970 Homeobox_CS IPR001356 Homeobox_dom IPR010982 Lambda_DNA-bd_dom_sf
Pfamⁱ	View protein in Pfam PF02376 CUT, 3 hits PF00046 Homeobox, 1 hit
SMARTⁱ	View protein in SMART SM01109 CUT, 3 hits SM00389 HOX, 1 hit
SUPFAMⁱ	SSF46689 SSF46689, 1 hit SSF47413 SSF47413, 3 hits
PROSITEⁱ	View protein in PROSITE PS51042 CUT, 3 hits PS00027 HOMEOBOX_1, 1 hit PS50071 HOMEOBOX_2, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q5BL05_MOUSE
Accessionⁱ	Q5BL05Primary (citable) accession number: Q5BL05
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	April 12, 2005
	Last sequence update:	April 12, 2005
	Last modified:	April 25, 2018
	This is version 121 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

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Supporting data

UniProtKB - Q5BL05 (Q5BL05_MOUSE)

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Homeobox protein cut-like

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Nucleus

Keywords - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Coiled coil

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

PTM / Processingⁱ

Expressionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ