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UniProtKB - Q5BL05 (Q5BL05_MOUSE)
Protein
Homeobox protein cut-like
Gene
Cux1
Organism
Mus musculus (Mouse)
Status
Functioni
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
DNA bindingi | 1150 – 1209 | HomeoboxPROSITE-ProRule annotationAdd BLAST | 60 |
GO - Molecular functioni
- DNA binding Source: UniProtKB-UniRule
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: InterPro
Keywordsi
Molecular function | DNA-bindingPROSITE-ProRule annotationARBA annotation |
Biological process | Transcription, Transcription regulationUniRule annotationARBA annotation |
Names & Taxonomyi
Protein namesi | Recommended name: Homeobox protein cut-likeUniRule annotation |
Gene namesi | |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Organism-specific databases
MGIi | MGI:88568, Cux1 |
Subcellular locationi
Nucleus
- Nucleus PROSITE-ProRule annotation
Nucleus
- nucleus Source: UniProtKB-SubCell
Keywords - Cellular componenti
NucleusPROSITE-ProRule annotationARBA annotationStructurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 451 – 538 | CUTInterPro annotationAdd BLAST | 88 | |
Domaini | 840 – 927 | CUTInterPro annotationAdd BLAST | 88 | |
Domaini | 1023 – 1110 | CUTInterPro annotationAdd BLAST | 88 | |
Domaini | 1148 – 1208 | HomeoboxInterPro annotationAdd BLAST | 61 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 410 – 457 | DisorderedSequence analysisAdd BLAST | 48 | |
Regioni | 555 – 577 | DisorderedSequence analysisAdd BLAST | 23 | |
Regioni | 591 – 613 | DisorderedSequence analysisAdd BLAST | 23 | |
Regioni | 680 – 782 | DisorderedSequence analysisAdd BLAST | 103 | |
Regioni | 795 – 834 | DisorderedSequence analysisAdd BLAST | 40 | |
Regioni | 943 – 1016 | DisorderedSequence analysisAdd BLAST | 74 | |
Regioni | 1118 – 1153 | DisorderedSequence analysisAdd BLAST | 36 | |
Regioni | 1218 – 1381 | DisorderedSequence analysisAdd BLAST | 164 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 17 – 37 | Sequence analysisAdd BLAST | 21 | |
Coiled coili | 68 – 88 | Sequence analysisAdd BLAST | 21 | |
Coiled coili | 112 – 196 | Sequence analysisAdd BLAST | 85 | |
Coiled coili | 201 – 228 | Sequence analysisAdd BLAST | 28 | |
Coiled coili | 237 – 274 | Sequence analysisAdd BLAST | 38 | |
Coiled coili | 296 – 355 | Sequence analysisAdd BLAST | 60 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 410 – 455 | Polar residuesSequence analysisAdd BLAST | 46 | |
Compositional biasi | 559 – 573 | Polar residuesSequence analysisAdd BLAST | 15 | |
Compositional biasi | 595 – 613 | Polar residuesSequence analysisAdd BLAST | 19 | |
Compositional biasi | 744 – 758 | Basic and acidic residuesSequence analysisAdd BLAST | 15 | |
Compositional biasi | 759 – 780 | Polar residuesSequence analysisAdd BLAST | 22 | |
Compositional biasi | 795 – 816 | Polar residuesSequence analysisAdd BLAST | 22 | |
Compositional biasi | 817 – 834 | Pro residuesSequence analysisAdd BLAST | 18 | |
Compositional biasi | 943 – 984 | Polar residuesSequence analysisAdd BLAST | 42 | |
Compositional biasi | 1218 – 1239 | Polar residuesSequence analysisAdd BLAST | 22 | |
Compositional biasi | 1360 – 1378 | Polar residuesSequence analysisAdd BLAST | 19 |
Sequence similaritiesi
Keywords - Domaini
Coiled coilSequence analysis, HomeoboxPROSITE-ProRule annotationARBA annotationPhylogenomic databases
OrthoDBi | 181575at2759 |
Family and domain databases
CDDi | cd00086, homeodomain, 1 hit |
Gene3Di | 1.10.260.40, 3 hits |
InterProi | View protein in InterPro IPR003350, CUT_dom IPR009057, Homeobox-like_sf IPR017970, Homeobox_CS IPR001356, Homeobox_dom IPR010982, Lambda_DNA-bd_dom_sf |
Pfami | View protein in Pfam PF02376, CUT, 3 hits PF00046, Homeodomain, 1 hit |
SMARTi | View protein in SMART SM01109, CUT, 3 hits SM00389, HOX, 1 hit |
SUPFAMi | SSF46689, SSF46689, 1 hit SSF47413, SSF47413, 3 hits |
PROSITEi | View protein in PROSITE PS51042, CUT, 3 hits PS00027, HOMEOBOX_1, 1 hit PS50071, HOMEOBOX_2, 1 hit |
i Sequence
Sequence statusi: Complete.
Q5BL05-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAANVGSMFQ YWKRFDLQQL QRELDATATV LANRQDESEQ SRKRLIEQSR
60 70 80 90 100
EFKKNTPEDL RKQVAPLLKS FQGEIDALSK RSKEAEAAFL TVYKRLIDVP
110 120 130 140 150
DPVPALDVGQ QLEIKVQRLH DIETENQKLR ETLEEYNKEF AEVKNQEVTI
160 170 180 190 200
KALKEKIREY EQTLKSQAET IALEKEQKLQ NDFAEKERKL QETQMSTTSK
210 220 230 240 250
LEEAEHKLQT LQTALEKTRT ELFDLKTKYD EETTAKADEI EMIMTDLERA
260 270 280 290 300
NQRAEVAQRE AETLREQLSS ANHSLQLASQ IQKAPDVEQA IEVLTRSSLE
310 320 330 340 350
VELAAKEREI AQLVEDVQRL QASLTKLREN SASQISQLEQ QLNAKNSTLK
360 370 380 390 400
QLEEKLKGQA DYEEVKKELN TLKSMEFAPS EGAGTQDSTK PLEVLLLEKN
410 420 430 440 450
RSLQSENATL RISNSDLSGP YSTNSISSPS PLQQSPDVNG MAPSPSQSES
460 470 480 490 500
AGSISEGEEI DTAEIARQVK EQLIKHNIGQ RIFGHYVLGL SQGSVSEILA
510 520 530 540 550
RPKPWNKLTV RGKEPFHKMK QFLSDEQNIL ALRSIQGRQR ENPGQSLNRL
560 570 580 590 600
FQEVPKRRNG SEGNITTRIR ASETGSDEAI KSILEQAKRE LQVQKTAEPV
610 620 630 640 650
QTSSTSSSGN SDDAIRSILQ QARREMEAQQ AALDPALKPA PLSQPDLTIL
660 670 680 690 700
TPKHLSASPM STVSTYPPLA ISLKKTPAAP ETSTAALPSA PALKKEAQDV
710 720 730 740 750
PTLDPPGSAD AAQGVLRPMK SELVRGSTWK DPWWSPIQPE RRNLTSSEET
760 770 780 790 800
KADETTASGK ERAGSSQPRA ERSQLQGPSA SAEYWKEWPS AESPYSQSSE
810 820 830 840 850
LSLTGASRSE TPQNSPLPSS PIVPMAKPAK PSVPPLTPEQ YEVYMYQEVD
860 870 880 890 900
TIELTRQVKE KLAKNGICQR IFGEKVLGLS QGSVSDMLSR PKPWSKLTQK
910 920 930 940 950
GREPFIRMQL WLNGELGQGV LPVQGQQQGP VLHSVASLQD PLQQGCVSSE
960 970 980 990 1000
STPKTSASCS PAPESPMSSS ESVKSLTELV QQPCPAIETS KEGKPPEPSD
1010 1020 1030 1040 1050
PPASDSQPTT PLPLSGHSAL SIQELVAMSP ELDTYGITKR VKEVLTDNNL
1060 1070 1080 1090 1100
GQRLFGETIL GLTQGSVSDL LARPKPWHKL SLKGREPFVR MQLWLNDPNN
1110 1120 1130 1140 1150
VEKLMDMKRM EKKAYMKRRH SSVSDSQPCE PPSVGIDYSQ GASPHPQHQL
1160 1170 1180 1190 1200
KKPRVVLAPE EKEALKRAYQ QKPYPSPKTI EELATQLNLK TSTVINWFHN
1210 1220 1230 1240 1250
YRSRIRRELF IEEIQAGSQG QAGASDSPSA RSSRAAPSSE GDSCDGVEAT
1260 1270 1280 1290 1300
DAEEPGGNIV ATKSQGGLAE VAAAPADREE ATQPAEKAKA QPLCSGTPGQ
1310 1320 1330 1340 1350
DDGEDASRPR PLPEGLADAP APVPSLAAPA AGEDAATSAT APATATEAPG
1360 1370 1380 1390 1400
AARAGPAERS SALPSTSAPA NAPARRPSSL QSLFGLPEAA GARDNLVRKK
1410 1420
KAANLNSIIH RLEKAASREE PIEWEF
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC090847 mRNA Translation: AAH90847.1 |
RefSeqi | NP_001278162.1, NM_001291233.1 NP_001278163.1, NM_001291234.1 NP_001278167.1, NM_001291238.1 NP_034116.3, NM_009986.4 NP_941004.2, NM_198602.3 |
Genome annotation databases
GeneIDi | 13047 |
KEGGi | mmu:13047 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC090847 mRNA Translation: AAH90847.1 |
RefSeqi | NP_001278162.1, NM_001291233.1 NP_001278163.1, NM_001291234.1 NP_001278167.1, NM_001291238.1 NP_034116.3, NM_009986.4 NP_941004.2, NM_198602.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
EPDi | Q5BL05 |
PeptideAtlasi | Q5BL05 |
Protocols and materials databases
DNASUi | 13047 |
Genome annotation databases
GeneIDi | 13047 |
KEGGi | mmu:13047 |
Organism-specific databases
CTDi | 1523 |
MGIi | MGI:88568, Cux1 |
Phylogenomic databases
OrthoDBi | 181575at2759 |
Miscellaneous databases
BioGRID-ORCSi | 13047, 6 hits in 73 CRISPR screens |
ChiTaRSi | Cux1, mouse |
SOURCEi | Search... |
Gene expression databases
Genevisiblei | Q5BL05, MM |
Family and domain databases
CDDi | cd00086, homeodomain, 1 hit |
Gene3Di | 1.10.260.40, 3 hits |
InterProi | View protein in InterPro IPR003350, CUT_dom IPR009057, Homeobox-like_sf IPR017970, Homeobox_CS IPR001356, Homeobox_dom IPR010982, Lambda_DNA-bd_dom_sf |
Pfami | View protein in Pfam PF02376, CUT, 3 hits PF00046, Homeodomain, 1 hit |
SMARTi | View protein in SMART SM01109, CUT, 3 hits SM00389, HOX, 1 hit |
SUPFAMi | SSF46689, SSF46689, 1 hit SSF47413, SSF47413, 3 hits |
PROSITEi | View protein in PROSITE PS51042, CUT, 3 hits PS00027, HOMEOBOX_1, 1 hit PS50071, HOMEOBOX_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Q5BL05_MOUSE | |
Accessioni | Q5BL05Primary (citable) accession number: Q5BL05 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 12, 2005 |
Last sequence update: | April 12, 2005 | |
Last modified: | May 25, 2022 | |
This is version 139 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |