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UniProtKB - Q5BKY9 (F133B_HUMAN)

Entry version 117 (02 Jun 2021)
Sequence version 1 (12 Apr 2005)
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Protein

Protein FAM133B

Gene

FAM133B

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q5BKY9

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein FAM133B
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:FAM133B
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:28629, FAM133B

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q5BKY9

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000234545.7

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		257415

Open Targets

More...OpenTargetsi		ENSG00000234545

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA162386138

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q5BKY9, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		FAM133B

Domain mapping of disease mutations (DMDM)

More...DMDMi		74736047

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002876161 – 247Protein FAM133BAdd BLAST247

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei82PhosphoserineCombined sources1
Modified residuei191PhosphoserineCombined sources1
Modified residuei192PhosphoserineCombined sources1
Modified residuei194PhosphoserineCombined sources1
Modified residuei196PhosphoserineCombined sources1

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q5BKY9

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q5BKY9

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q5BKY9

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q5BKY9

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q5BKY9

PeptideAtlas

More...PeptideAtlasi		Q5BKY9

PRoteomics IDEntifications database

More...PRIDEi		Q5BKY9

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		62711 [Q5BKY9-1]
62712 [Q5BKY9-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q5BKY9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q5BKY9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000234545, Expressed in frontal cortex and 121 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q5BKY9, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q5BKY9, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000234545, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		129218, 13 interactors

Protein interaction database and analysis system

More...IntActi		Q5BKY9, 5 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000398401

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q5BKY9, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q5BKY9

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni19 – 38DisorderedSequence analysisAdd BLAST20
Regioni70 – 247DisorderedSequence analysisAdd BLAST178

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi70 – 90Basic and acidic residuesSequence analysisAdd BLAST21
Compositional biasi141 – 188Basic and acidic residuesSequence analysisAdd BLAST48
Compositional biasi198 – 220Basic and acidic residuesSequence analysisAdd BLAST23
Compositional biasi221 – 238Basic residuesSequence analysisAdd BLAST18

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the FAM133 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502QWN4, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00730000111097

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_108741_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q5BKY9

Identification of Orthologs from Complete Genome Data

More...OMAi		PTWDDLK

Database of Orthologous Groups

More...OrthoDBi		1561261at2759

TreeFam database of animal gene trees

More...TreeFami		TF350193

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR026766, Fam133

The PANTHER Classification System

More...PANTHERi		PTHR31911, PTHR31911, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q5BKY9-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MGKRDNRVAY MNPIAMARSR GPIQSSGPTI QDYLNRPRPT WEEVKEQLEK 
        60         70         80         90        100
KKKGSKALAE FEEKMNENWK KELEKHREKL LSGSESSSKK RQRKKKEKKK 
       110        120        130        140        150
SGRYSSSSSS SSDSSSSSSD SEDEDKKQGK RRKKKKNRSH KSSESSMSET 
       160        170        180        190        200
ESDSKDSLKK KKKSKDGTEK EKDIKGLSKK RKMYSEDKPL SSESLSESEY 
       210        220        230        240 
IEEVRAKKKK SSEEREKATE KTKKKKKHKK HSKKKKKKAA SSSPDSP
Length:247
Mass (Da):28,385
Last modified:April 12, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE6713614B2BE0D48
GO
Isoform 2 (identifier: Q5BKY9-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-10: Missing.

Show »
Length:237
Mass (Da):27,194
Checksum:iE2A9AA702B378154
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
G3XAI9G3XAI9_HUMAN
Protein FAM133B
FAM133B MGC40405, hCG_19545
105Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YH72H0YH72_HUMAN
Protein FAM133B
FAM133B
120Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JUX2C9JUX2_HUMAN
Protein FAM133B
FAM133B
30Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0255711 – 10Missing in isoform 2. 3 Publications10

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AK313692 mRNA Translation: BAG36441.1
AL833918 mRNA Translation: CAD38774.1
CH236949 Genomic DNA Translation: EAL24147.1
CH471091 Genomic DNA Translation: EAW76831.1
BC017874 mRNA Translation: AAH17874.1 Different termination.
BC032461 mRNA Translation: AAH32461.1
BC057771 mRNA Translation: AAH57771.1
BC062706 mRNA Translation: AAH62706.1 Different termination.
BC090868 mRNA Translation: AAH90868.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS47640.1 [Q5BKY9-1]
CCDS47641.1 [Q5BKY9-2]

NCBI Reference Sequences

More...RefSeqi		NP_001035146.1, NM_001040057.2 [Q5BKY9-2]
NP_001275513.1, NM_001288584.1 [Q5BKY9-2]
NP_690002.2, NM_152789.3 [Q5BKY9-1]
XP_011514306.1, XM_011516004.2 [Q5BKY9-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000427372; ENSP00000402843; ENSG00000234545 [Q5BKY9-2]
ENST00000438306; ENSP00000389783; ENSG00000234545 [Q5BKY9-2]
ENST00000445716; ENSP00000398401; ENSG00000234545 [Q5BKY9-1]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		257415

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:257415

UCSC genome browser

More...UCSCi		uc003umb.5, human [Q5BKY9-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK313692 mRNA Translation: BAG36441.1
AL833918 mRNA Translation: CAD38774.1
CH236949 Genomic DNA Translation: EAL24147.1
CH471091 Genomic DNA Translation: EAW76831.1
BC017874 mRNA Translation: AAH17874.1 Different termination.
BC032461 mRNA Translation: AAH32461.1
BC057771 mRNA Translation: AAH57771.1
BC062706 mRNA Translation: AAH62706.1 Different termination.
BC090868 mRNA Translation: AAH90868.1
CCDSiCCDS47640.1 [Q5BKY9-1]
CCDS47641.1 [Q5BKY9-2]
RefSeqiNP_001035146.1, NM_001040057.2 [Q5BKY9-2]
NP_001275513.1, NM_001288584.1 [Q5BKY9-2]
NP_690002.2, NM_152789.3 [Q5BKY9-1]
XP_011514306.1, XM_011516004.2 [Q5BKY9-2]

3D structure databases

SMRiQ5BKY9
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi129218, 13 interactors
IntActiQ5BKY9, 5 interactors
STRINGi9606.ENSP00000398401

PTM databases

iPTMnetiQ5BKY9
PhosphoSitePlusiQ5BKY9

Genetic variation databases

BioMutaiFAM133B
DMDMi74736047

Proteomic databases

EPDiQ5BKY9
jPOSTiQ5BKY9
MassIVEiQ5BKY9
MaxQBiQ5BKY9
PaxDbiQ5BKY9
PeptideAtlasiQ5BKY9
PRIDEiQ5BKY9
ProteomicsDBi62711 [Q5BKY9-1]
62712 [Q5BKY9-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		58077, 36 antibodies

The DNASU plasmid repository

More...DNASUi		257415

Genome annotation databases

EnsembliENST00000427372; ENSP00000402843; ENSG00000234545 [Q5BKY9-2]
ENST00000438306; ENSP00000389783; ENSG00000234545 [Q5BKY9-2]
ENST00000445716; ENSP00000398401; ENSG00000234545 [Q5BKY9-1]
GeneIDi257415
KEGGihsa:257415
UCSCiuc003umb.5, human [Q5BKY9-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		257415
DisGeNETi257415

GeneCards: human genes, protein and diseases

More...GeneCardsi		FAM133B
HGNCiHGNC:28629, FAM133B
HPAiENSG00000234545, Low tissue specificity
neXtProtiNX_Q5BKY9
OpenTargetsiENSG00000234545
PharmGKBiPA162386138
VEuPathDBiHostDB:ENSG00000234545.7

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG502QWN4, Eukaryota
GeneTreeiENSGT00730000111097
HOGENOMiCLU_108741_0_0_1
InParanoidiQ5BKY9
OMAiPTWDDLK
OrthoDBi1561261at2759
TreeFamiTF350193

Enzyme and pathway databases

PathwayCommonsiQ5BKY9

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		257415, 312 hits in 931 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		FAM133B, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		257415
PharosiQ5BKY9, Tdark

Protein Ontology

More...PROi		PR:Q5BKY9
RNActiQ5BKY9, protein

Gene expression databases

BgeeiENSG00000234545, Expressed in frontal cortex and 121 other tissues
ExpressionAtlasiQ5BKY9, baseline and differential
GenevisibleiQ5BKY9, HS

Family and domain databases

InterProiView protein in InterPro
IPR026766, Fam133
PANTHERiPTHR31911, PTHR31911, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF133B_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5BKY9
Secondary accession number(s): B2R994
, Q05D67, Q6P5S6, Q8N0W8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: April 12, 2005
Last modified: June 2, 2021
This is version 117 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
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