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Protein
Submitted name:

C9 protein

Gene

C9

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
C9 proteinImported
Gene namesi
Name:C9Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 33Sequence analysisAdd BLAST33
ChainiPRO_500425359934 – 567Sequence analysisAdd BLAST534

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi118 ↔ 136PROSITE-ProRule annotation
Disulfide bondi130 ↔ 145PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Proteomic databases

PRIDEiQ5BKC4

Structurei

3D structure databases

ProteinModelPortaliQ5BKC4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini149 – 531MACPFInterPro annotationAdd BLAST383

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili506 – 526Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IH3C Eukaryota
ENOG410XT9A LUCA
HOGENOMiHOG000111869
HOVERGENiHBG106792
OrthoDBiEOG091G07LK
PhylomeDBiQ5BKC4
TreeFamiTF330498

Family and domain databases

CDDicd00112 LDLa, 1 hit
InterProiView protein in InterPro
IPR037567 Complement_C9
IPR009030 Growth_fac_rcpt_cys_sf
IPR036055 LDL_receptor-like_sf
IPR023415 LDLR_class-A_CS
IPR002172 LDrepeatLR_classA_rpt
IPR001862 MAC_perforin
IPR020864 MACPF
IPR020863 MACPF_CS
IPR000884 TSP1_rpt
IPR036383 TSP1_rpt_sf
PANTHERiPTHR19325:SF362 PTHR19325:SF362, 1 hit
PfamiView protein in Pfam
PF00057 Ldl_recept_a, 1 hit
PF01823 MACPF, 1 hit
PF00090 TSP_1, 1 hit
PRINTSiPR00764 COMPLEMENTC9
SMARTiView protein in SMART
SM00192 LDLa, 1 hit
SM00457 MACPF, 1 hit
SM00209 TSP1, 1 hit
SUPFAMiSSF57184 SSF57184, 2 hits
SSF57424 SSF57424, 1 hit
SSF82895 SSF82895, 1 hit
PROSITEiView protein in PROSITE
PS01209 LDLRA_1, 1 hit
PS50068 LDLRA_2, 1 hit
PS00279 MACPF_1, 1 hit
PS51412 MACPF_2, 1 hit
PS50092 TSP1, 1 hit

Sequencei

Sequence statusi: Complete.

Q5BKC4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLLRTPGLPR RSGMASGVTI TLAIAIFALE INAQAPEPTP REEPSADALL
60 70 80 90 100
PIDCRMSTWS QWSQCDPCLK QRFRSRSIEV FGQFQGKSCA DALGDRQHCE
110 120 130 140 150
PTQECEEVQE NCGNDFQCET GRCIKRKLLC NGDNDCGDFS DESDCESDPR
160 170 180 190 200
LPCRDRVVEE SELGRTAGYG INILGMDPLG TPFDNEFYNG LCDRVRDGNT
210 220 230 240 250
LTYYRKPWNV AFLAYETKAD KNFRTENYEE QFEMFKTIVR DRTTSFNANL
260 270 280 290 300
ALKFTITEAP IKKVGVDEVS PEKNSSKPKD SSVDFQFSYF KKENFQRLSS
310 320 330 340 350
YLSQTKKMFL HVRGMIQLGR FVMRNRGVML TTTFLDDVKA LPVSYEKGEY
360 370 380 390 400
FGFLETYGTH YSSSGSLGGL YELIYVLDKA SMKEKGVELS DVKRCLGFNL
410 420 430 440 450
DVSLYTPLQT TLEGPSLTAN VNHSDCLKTG DGKVVNISRD HIIDDVISFI
460 470 480 490 500
RGGTRKQAVL LKEKLLRGAK TIDVNDFINW ASSLDDAPAL ISQKLSPIYN
510 520 530 540 550
LIPLTMKDAY AKKQNMEKAI EDYVNEFSAR KCYPCQNGGT AILLDGQCMC
560
SCTIKFKGIA CEISKQR
Length:567
Mass (Da):63,775
Last modified:April 12, 2005 - v1
Checksum:i7FA995A728065518
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC091127 mRNA Translation: AAH91127.1
UniGeneiRn.10252

Similar proteinsi

Entry informationi

Entry nameiQ5BKC4_RAT
AccessioniPrimary (citable) accession number: Q5BKC4
Entry historyiIntegrated into UniProtKB/TrEMBL: April 12, 2005
Last sequence update: April 12, 2005
Last modified: July 18, 2018
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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