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Entry version 102 (07 Apr 2021)
Sequence version 2 (10 Jul 2007)
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Protein

Patatin-like phospholipase domain-containing protein 7

Gene

Pnpla7

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Lysophospholipase which preferentially deacylates unsaturated lysophosphatidylcholine (C18:1), generating glycerophosphocholine. Also can deacylate, to a lesser extent, lysophosphatidylethanolamine (C18:1), lysophosphatidyl-L-serine (C18:1) and lysophosphatidic acid (C16:0).By similarity

Caution

It is uncertain whether Met-1 or Met-27 is the initiator.Curated

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei980NucleophilePROSITE-ProRule annotation1
Active sitei1100Proton acceptorPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi170 – 297cNMP 1PROSITE-ProRule annotationAdd BLAST128
Nucleotide bindingi496 – 599cNMP 2PROSITE-ProRule annotationAdd BLAST104
Nucleotide bindingi610 – 715cNMP 3PROSITE-ProRule annotationAdd BLAST106

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • carboxylic ester hydrolase activity Source: RGD
  • lysophospholipase activity Source: UniProtKB
  • phosphatidyl phospholipase B activity Source: UniProtKB-EC

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase
Biological processLipid degradation, Lipid metabolism

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Patatin-like phospholipase domain-containing protein 7 (EC:3.1.1.-1 Publication, EC:3.1.1.5By similarity)
Alternative name(s):
Liver NTE-related protein 1
NTE-related esterase
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Pnpla7
Synonyms:Nre, Ntel1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRattus norvegicus (Rat)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10116 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002494 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

Organism-specific databases

Rat genome database

More...
RGDi
708466, Pnpla7

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 36LumenalCuratedAdd BLAST36
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei37 – 57HelicalSequence analysisAdd BLAST21
Topological domaini58 – 1349CytoplasmicCuratedAdd BLAST1292

Keywords - Cellular componenti

Endoplasmic reticulum, Lipid droplet, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi980S → A, C, D or H: Abolishes hydrolytic activity. 1 Publication1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002934911 – 1349Patatin-like phospholipase domain-containing protein 7Add BLAST1349

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei341PhosphoserineCombined sources1
Modified residuei377PhosphoserineBy similarity1
Modified residuei1277PhosphoserineCombined sources1
Modified residuei1281PhosphothreonineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q5BK26

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q5BK26

PRoteomics IDEntifications database

More...
PRIDEi
Q5BK26

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...
GlyGeni
Q5BK26, 5 sites

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q5BK26

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q5BK26

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in the brain, liver, kidney, lung and testis.1 Publication

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10116.ENSRNOP00000011633

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q5BK26

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini947 – 1113PNPLAPROSITE-ProRule annotationAdd BLAST167

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni678 – 964Involved in the binding to lipid dropletsBy similarityAdd BLAST287

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi951 – 956GXGXXGPROSITE-ProRule annotation6
Motifi978 – 982GXSXGPROSITE-ProRule annotation5
Motifi1100 – 1102DGA/GPROSITE-ProRule annotation3

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The 3 cNMP binding domains are required for localization to the endoplasmic reticulum. The cNMP binding domain 3 is involved in the binding to lipid droplets.By similarity

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the NTE family.Curated

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2968, Eukaryota

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q5BK26

Database of Orthologous Groups

More...
OrthoDBi
253518at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q5BK26

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00038, CAP_ED, 3 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.120.10, 3 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016035, Acyl_Trfase/lysoPLipase
IPR018490, cNMP-bd-like
IPR000595, cNMP-bd_dom
IPR002641, PNPLA_dom
IPR014710, RmlC-like_jellyroll

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00027, cNMP_binding, 3 hits
PF01734, Patatin, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00100, cNMP, 3 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF51206, SSF51206, 3 hits
SSF52151, SSF52151, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50042, CNMP_BINDING_3, 3 hits
PS51635, PNPLA, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q5BK26-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQKEEDVCPE AGYCLGTALS SWGLHFMEEH SQSTMLMGIG IGVLLTLAFV
60 70 80 90 100
GLAAFFVYRK VSRFRRAEPI PQYRFRKRDK VMFYGRKIMR KVTTLPHTLV
110 120 130 140 150
GNTAAPRQRV RKRTKVLSLA KRILRFKKEY PTLQPKEPPP SLLEADLTEF
160 170 180 190 200
DVKNSHLPSE VLYMLKNVRV LGHFEKPLFL ELCKHMVFVQ LQEGEHVFQP
210 220 230 240 250
GEPDISIYVV QDGRLEVCIQ DADGTEVVVK EVLPGDSVHS LLSILDVITG
260 270 280 290 300
HTAPYKTVSA RAAVASTVLW LPAAAFQGVF EKYPETLVRV VQIIMVRLQR
310 320 330 340 350
VTFLALHNYL GLTTELFNPE SQAIPLLSVA SVAGRAKRQM SYGPEEQLER
360 370 380 390 400
SPRLSEFNSS DQRSVAVSGP LLKRSCSVPL PPIHGEIDEL RQAQGSGSNT
410 420 430 440 450
SAFQESQEGA TSDLGMAYNR ARILPHSEEQ LGSSLASKSK KSVVAETSAV
460 470 480 490 500
FHYSEKPRDE PGPSGRTDAI FRAATKDLLT LMKLDDPSLL DGRVAFLHVP
510 520 530 540 550
AGTIVSKQGD QDVNILFVVS GMLHVYQQKI DSLEDTCLFL THPGEMVGQL
560 570 580 590 600
AVLTGEPLMF TIRANRDCSF LSISKAHFYE IMRKRPDVVL GVAHTVVRRM
610 620 630 640 650
SSFVRQIDFA LDWMEVEAGR AIYRQGDKSD CTYIVLSGRL RSVIRKDDGK
660 670 680 690 700
KRLAGEYGRG DLVGVVEMLT HQARATTVHA VRDSELAKLP AGALTSIKRR
710 720 730 740 750
YPQVVTRLIH LLGEKILGSL QQGSGTGHQL GFNTASSKWD LGNPPGNLST
760 770 780 790 800
VAAMPVSEDV PLTAFALELQ HALSAIGPVL LLTSDNIKQR LGSAALDSIH
810 820 830 840 850
EYRLSSWLGQ QEDIHRIVLY QADSTLTPWT QRCIRQADCI LIVGLGDQEP
860 870 880 890 900
ALGELEQMLE STAVRAQKQL ILLHKEEGPA PSRTVEWLNM RSWCSGHLHL
910 920 930 940 950
CCPRRVFSKR SLPKLVEMYT RIFQRPPDRH SDFSRLARIL TGNAIALVLG
960 970 980 990 1000
GGGARGCAQV GILRALAECG IPVDIIGGTS IGAFMGALFA EERSYSQIRI
1010 1020 1030 1040 1050
RAKQWAEDMT SMVKTILDLT YPITSMFSGT GFNSSISNIF KDRQIEDLWL
1060 1070 1080 1090 1100
PYFAITTDIT ASAMRVHTDG ALWRYVRASM SLSGYMPPLC DPKDGHLLMD
1110 1120 1130 1140 1150
GGYINNLPAD VARSMGAKVV IAIDVGSRDE TDLTNYGDAL SGWWLLWKRW
1160 1170 1180 1190 1200
NPLATKVKVL NMAEIQTRLA YVCCVRQLEM VKNSDYCEYL RPPIDSYRTL
1210 1220 1230 1240 1250
DFGKFDEICE VGYQHGPAGF DIWVRSGVLE KMLQDQQGTS KRMDCGVFTC
1260 1270 1280 1290 1300
PNSSFTDLAE IVSRIEPAKV AAVDDESDYQ TEYEEELPAI PKETYADFQS
1310 1320 1330 1340
TGIELDSDSE CEPSMSQGPH SLTSPKQSQD SFPWLPNQDD QGPRLYRPS
Length:1,349
Mass (Da):150,024
Last modified:July 10, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4312292A0CFE2FDD
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
G3V745G3V745_RAT
Neuropathy target esterase like 1
Pnpla7 Ntel1, rCG_45438
1,349Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH91230 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti956 – 957GC → CT in AAH91230 (PubMed:15489334).Curated2
Sequence conflicti1071A → S in AAH83547 (PubMed:15489334).Curated1
Sequence conflicti1217 – 1219PAG → RTV in AAH83547 (PubMed:15489334).Curated3

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BC083547 mRNA Translation: AAH83547.2
BC091230 mRNA Translation: AAH91230.1 Different initiation.
AY100477 mRNA Translation: AAM44077.1

NCBI Reference Sequences

More...
RefSeqi
NP_653339.2, NM_144738.2

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
246246

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
rno:246246

UCSC genome browser

More...
UCSCi
RGD:708466, rat

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC083547 mRNA Translation: AAH83547.2
BC091230 mRNA Translation: AAH91230.1 Different initiation.
AY100477 mRNA Translation: AAM44077.1
RefSeqiNP_653339.2, NM_144738.2

3D structure databases

SMRiQ5BK26
ModBaseiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000011633

PTM databases

GlyGeniQ5BK26, 5 sites
iPTMnetiQ5BK26
PhosphoSitePlusiQ5BK26

Proteomic databases

jPOSTiQ5BK26
PaxDbiQ5BK26
PRIDEiQ5BK26

Genome annotation databases

GeneIDi246246
KEGGirno:246246
UCSCiRGD:708466, rat

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
375775
RGDi708466, Pnpla7

Phylogenomic databases

eggNOGiKOG2968, Eukaryota
InParanoidiQ5BK26
OrthoDBi253518at2759
PhylomeDBiQ5BK26

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q5BK26

Family and domain databases

CDDicd00038, CAP_ED, 3 hits
Gene3Di2.60.120.10, 3 hits
InterProiView protein in InterPro
IPR016035, Acyl_Trfase/lysoPLipase
IPR018490, cNMP-bd-like
IPR000595, cNMP-bd_dom
IPR002641, PNPLA_dom
IPR014710, RmlC-like_jellyroll
PfamiView protein in Pfam
PF00027, cNMP_binding, 3 hits
PF01734, Patatin, 1 hit
SMARTiView protein in SMART
SM00100, cNMP, 3 hits
SUPFAMiSSF51206, SSF51206, 3 hits
SSF52151, SSF52151, 1 hit
PROSITEiView protein in PROSITE
PS50042, CNMP_BINDING_3, 3 hits
PS51635, PNPLA, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPLPL7_RAT
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5BK26
Secondary accession number(s): Q5XIX2, Q8K3H9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: July 10, 2007
Last modified: April 7, 2021
This is version 102 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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