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UniProtKB - Q5BJG6 (Q5BJG6_HUMAN)

Entry version 107 (07 Apr 2021)
Sequence version 1 (12 Apr 2005)
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Protein
Submitted name:

ZMYND11 protein

Gene

ZMYND11

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
ZMYND11 proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZMYND11Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA128394578

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q5BJG6

PeptideAtlas

More...PeptideAtlasi		Q5BJG6

PRoteomics IDEntifications database

More...PRIDEi		Q5BJG6

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		62689

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q5BJG6, HS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...IntActi		Q5BJG6, 2 interactors

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q5BJG6

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini92 – 144BromoInterPro annotationAdd BLAST53
Domaini186 – 237PWWPInterPro annotationAdd BLAST52
Domaini469 – 504MYND-typeInterPro annotationAdd BLAST36

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni272 – 365DisorderedSequence analysisAdd BLAST94

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili393 – 424Sequence analysisAdd BLAST32
Coiled coili442 – 462Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi296 – 321PolyampholyteSequence analysisAdd BLAST26
Compositional biasi323 – 365PolarSequence analysisAdd BLAST43

Keywords - Domaini

BromodomainPROSITE-ProRule annotation, Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotation

Family and domain databases

Conserved Domains Database

More...CDDi		cd05841, BS69_related, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.20.920.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR001487, Bromodomain
IPR036427, Bromodomain-like_sf
IPR000313, PWWP_dom
IPR035505, ZMYND8/11_PWWP
IPR002893, Znf_MYND

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00439, Bromodomain, 1 hit
PF00855, PWWP, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00297, BROMO, 1 hit
SM00293, PWWP, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF47370, SSF47370, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50014, BROMODOMAIN_2, 1 hit
PS50812, PWWP, 1 hit
PS01360, ZF_MYND_1, 1 hit
PS50865, ZF_MYND_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q5BJG6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSRVHGMHPK ETTRQLSLAV KDGLIVETLT VGCKGSKAGI EQEGYWLPGD 
        60         70         80         90        100
EISIKKKNTN KQEMGTYLRF IVSRMKERAI DLNKKGKDNK HPMYRRLVHS 
       110        120        130        140        150
AVDVPTIQEK VNEGKYRSYE EFKADAQLLL HNTVIFYGAD SEQADIARML 
       160        170        180        190        200
YKDTCHELDE LQLCKNCFYL SNARPDNWFC YPCIPNHELV WAKMKGFGFW 
       210        220        230        240        250
PAKVMQKEDN QVDVRFFGHH HQRAWIPSEN IQDITVNIHR LHVKRSMGWK 
       260        270        280        290        300
KACDELELHQ RFLREGRFWK SKNEDRGEEE AESSISSTSN EQLKVTQEPR 
       310        320        330        340        350
AKKGRRNQSV EPKKEEPEPE TEAVSSSQEI PTMPQPIEKV SVSTQTKKLS 
       360        370        380        390        400
ASSPRMLHRS TQTTNDGVCQ SMCHDKYTKI FNDFKDRMKS DHKRETERVV 
       410        420        430        440        450
REALEKLRSE MEEEKRQAVN KAVANMQGEM DRKCKQVKEK CKEEFVEEIK 
       460        470        480        490        500
KLATQHKQLI SQTKKKQWCY NCEEEAMYHC CWNTSYCSIK CQQEHWHAEH 

KRTCRRKR
Length:508
Mass (Da):59,666
Last modified:April 12, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0038F7B3D96C7181
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
BC091489 mRNA Translation: AAH91489.1

NCBI Reference Sequences

More...RefSeqi		NP_001189393.1, NM_001202464.1
NP_001189394.1, NM_001202465.1
NP_001189395.1, NM_001202466.1
NP_006615.2, NM_006624.5

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...GeneIDi		10771

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:10771

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC091489 mRNA Translation: AAH91489.1
RefSeqiNP_001189393.1, NM_001202464.1
NP_001189394.1, NM_001202465.1
NP_001189395.1, NM_001202466.1
NP_006615.2, NM_006624.5

3D structure databases

SMRiQ5BJG6
ModBaseiSearch...

Protein-protein interaction databases

IntActiQ5BJG6, 2 interactors

Proteomic databases

MaxQBiQ5BJG6
PeptideAtlasiQ5BJG6
PRIDEiQ5BJG6
ProteomicsDBi62689

Protocols and materials databases

The DNASU plasmid repository

More...DNASUi		10771

Genome annotation databases

GeneIDi10771
KEGGihsa:10771

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		10771
PharmGKBiPA128394578

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		10771, 9 hits in 1000 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		ZMYND11, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		10771

Gene expression databases

GenevisibleiQ5BJG6, HS

Family and domain databases

CDDicd05841, BS69_related, 1 hit
Gene3Di1.20.920.10, 1 hit
InterProiView protein in InterPro
IPR001487, Bromodomain
IPR036427, Bromodomain-like_sf
IPR000313, PWWP_dom
IPR035505, ZMYND8/11_PWWP
IPR002893, Znf_MYND
PfamiView protein in Pfam
PF00439, Bromodomain, 1 hit
PF00855, PWWP, 1 hit
SMARTiView protein in SMART
SM00297, BROMO, 1 hit
SM00293, PWWP, 1 hit
SUPFAMiSSF47370, SSF47370, 1 hit
PROSITEiView protein in PROSITE
PS50014, BROMODOMAIN_2, 1 hit
PS50812, PWWP, 1 hit
PS01360, ZF_MYND_1, 1 hit
PS50865, ZF_MYND_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ5BJG6_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5BJG6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 12, 2005
Last sequence update: April 12, 2005
Last modified: April 7, 2021
This is version 107 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
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