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Entry version 93 (08 May 2019)
Sequence version 3 (14 Oct 2008)
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Protein

Coiled-coil domain-containing protein 178

Gene

CCDC178

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Coiled-coil domain-containing protein 178
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CCDC178
Synonyms:C18orf34
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 18

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:29588 CCDC178

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q5BJE1

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
374864

Open Targets

More...
OpenTargetsi
ENSG00000166960

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134979792

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
CCDC178

Domain mapping of disease mutations (DMDM)

More...
DMDMi
209572750

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002233161 – 867Coiled-coil domain-containing protein 178Add BLAST867

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q5BJE1

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q5BJE1

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q5BJE1

PeptideAtlas

More...
PeptideAtlasi
Q5BJE1

PRoteomics IDEntifications database

More...
PRIDEi
Q5BJE1

ProteomicsDB human proteome resource

More...
ProteomicsDBi
62676
62677 [Q5BJE1-2]
62678 [Q5BJE1-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q5BJE1

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q5BJE1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000166960 Expressed in 95 organ(s), highest expression level in sperm

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q5BJE1 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q5BJE1 HS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q5BJE1, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000372576

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q5BJE1

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili153 – 204Sequence analysisAdd BLAST52
Coiled coili233 – 414Sequence analysisAdd BLAST182
Coiled coili445 – 470Sequence analysisAdd BLAST26
Coiled coili662 – 696Sequence analysisAdd BLAST35

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IIKF Eukaryota
ENOG411202Z LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000012215

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q5BJE1

Database of Orthologous Groups

More...
OrthoDBi
710456at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q5BJE1

TreeFam database of animal gene trees

More...
TreeFami
TF337479

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR038826 CCDC178

The PANTHER Classification System

More...
PANTHERi
PTHR35088 PTHR35088, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 6 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q5BJE1-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MTENKTVSSS STRDDQTNIG LTCQEVKALR EKAWSRTNEG NAMSQSLVLY
60 70 80 90 100
GASKENSEGF HESKMTNTEG VNKGIYFSYP CRRHSCAVVN IPAPCVNKMI
110 120 130 140 150
SHIQDVESKI QEHLKRFETS FEEWSRTSST KDLKEDWSVT TPVKEVKPGE
160 170 180 190 200
KRDEKCPELK QEMETLLSEA IRLIKSLETD RADAEEALKQ QRSRKNMINM
210 220 230 240 250
KIDSWSVWKL QELPLAVQKE HEAYLSDVIE LQWHLEDKAN QLQHFEKQKT
260 270 280 290 300
ELEEANAKIQ ADIDYMNEHG PLLDSKQNQE LQDLKNHYKK KMEVMDLHRK
310 320 330 340 350
VNEELEEALE ACENARLKAQ QIKEEIDKDI YQDEKTIEAY KREIYQLNSL
360 370 380 390 400
FDHYSSSVIN VNTNIEEKEE EVTEAIRETK SSKNELHSLS KMLEDLRRVY
410 420 430 440 450
DQLTWKQKSH ENQYLEAVND FYAAKKTWDI ELSDVAKDFS AISLACTKLT
460 470 480 490 500
EDNKKLEIDI NKITVKTNES IRKKSKYESE IKYLTIMKLK NDKHLKNIYK
510 520 530 540 550
EAYRIGTLFH LTKHKTDEME DKIAEVRRKF KGREEFLKKL TQGEVAAGMV
560 570 580 590 600
LQKKLYSIYE VQALERKELI KNRAICAMSL AELQEPLLQL EDEAERIRSL
610 620 630 640 650
DKEHSVMLNN IIDQKDLIRR KVGKVKKKLR KKGKKTLDAL IETESKRSAI
660 670 680 690 700
FKDLEATKSK TMIFYAKINE LNEELKAKEE EKKSFDQTLE ILKNKFITMR
710 720 730 740 750
FKREHAQTVF DHYMQEKKDC EERIFEEDQR FRVLLAVRQK TLQDTQKIIA
760 770 780 790 800
DSLEENLRLA QEYQQLQITF LKEKDNYFNI YDKQLSLDTS IRDKKQLCQL
810 820 830 840 850
QRRMHTLWQE HFKLVVLFSQ MRLANFQTDS QESIQKILAV QEESSNLMQH
860
ILGFFQTLTD GTCENDG
Length:867
Mass (Da):102,011
Last modified:October 14, 2008 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i665719B544E55E9B
GO
Isoform 2 (identifier: Q5BJE1-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     607-644: Missing.

Note: No experimental confirmation available.
Show »
Length:829
Mass (Da):97,566
Checksum:i74AAC4DA845C6B2C
GO
Isoform 3 (identifier: Q5BJE1-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     747-796: Missing.

Note: No experimental confirmation available.
Show »
Length:817
Mass (Da):95,979
Checksum:i6E17C0996B9FAD6C
GO
Isoform 4 (identifier: Q5BJE1-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     842-867: EESSNLMQHILGFFQTLTDGTCENDG → NQYDLEKE

Note: No experimental confirmation available.
Show »
Length:849
Mass (Da):100,162
Checksum:i7C78EDC4C77A8845
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0A0MS97A0A0A0MS97_HUMAN
Coiled-coil domain-containing prote...
CCDC178
291Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8W7A7F8W7A7_HUMAN
Coiled-coil domain-containing prote...
CCDC178
891Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3KSU3J3KSU3_HUMAN
Coiled-coil domain-containing prote...
CCDC178
364Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3KRT5J3KRT5_HUMAN
Coiled-coil domain-containing prote...
CCDC178
187Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3QRM8J3QRM8_HUMAN
Coiled-coil domain-containing prote...
CCDC178
72Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3QKU2J3QKU2_HUMAN
Coiled-coil domain-containing prote...
CCDC178
103Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAC85257 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti49L → I in BAC86407 (PubMed:14702039).Curated1
Sequence conflicti368K → E in BAC86407 (PubMed:14702039).Curated1
Sequence conflicti768I → F in BAC86407 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_04701042A → T. Corresponds to variant dbSNP:rs12606658Ensembl.1
Natural variantiVAR_061624420D → N. Corresponds to variant dbSNP:rs58448816Ensembl.1
Natural variantiVAR_047011465V → E1 PublicationCorresponds to variant dbSNP:rs9965081Ensembl.1
Natural variantiVAR_047012600L → R. Corresponds to variant dbSNP:rs457896Ensembl.1
Natural variantiVAR_047013601D → N1 PublicationCorresponds to variant dbSNP:rs466113Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_017257607 – 644Missing in isoform 2. 1 PublicationAdd BLAST38
Alternative sequenceiVSP_017258747 – 796Missing in isoform 3. 1 PublicationAdd BLAST50
Alternative sequenceiVSP_053415842 – 867EESSN…CENDG → NQYDLEKE in isoform 4. 1 PublicationAdd BLAST26

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK126038 mRNA Translation: BAC86407.1
AK129955 mRNA Translation: BAC85257.1 Different initiation.
AC025888 Genomic DNA No translation available.
AC090371 Genomic DNA No translation available.
AC100845 Genomic DNA No translation available.
AC104956 Genomic DNA No translation available.
AC116607 Genomic DNA No translation available.
BC091517 mRNA Translation: AAH91517.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS11906.1 [Q5BJE1-2]
CCDS42424.1 [Q5BJE1-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001098998.1, NM_001105528.1 [Q5BJE1-1]
NP_001295055.1, NM_001308126.1
NP_945346.2, NM_198995.2 [Q5BJE1-2]
XP_011524250.1, XM_011525948.1 [Q5BJE1-1]
XP_011524253.1, XM_011525951.1 [Q5BJE1-3]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000300227; ENSP00000300227; ENSG00000166960 [Q5BJE1-2]
ENST00000383096; ENSP00000372576; ENSG00000166960 [Q5BJE1-1]
ENST00000403303; ENSP00000385591; ENSG00000166960 [Q5BJE1-1]
ENST00000579947; ENSP00000462370; ENSG00000166960 [Q5BJE1-4]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
374864

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:374864

UCSC genome browser

More...
UCSCi
uc002kxn.3 human [Q5BJE1-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK126038 mRNA Translation: BAC86407.1
AK129955 mRNA Translation: BAC85257.1 Different initiation.
AC025888 Genomic DNA No translation available.
AC090371 Genomic DNA No translation available.
AC100845 Genomic DNA No translation available.
AC104956 Genomic DNA No translation available.
AC116607 Genomic DNA No translation available.
BC091517 mRNA Translation: AAH91517.1
CCDSiCCDS11906.1 [Q5BJE1-2]
CCDS42424.1 [Q5BJE1-1]
RefSeqiNP_001098998.1, NM_001105528.1 [Q5BJE1-1]
NP_001295055.1, NM_001308126.1
NP_945346.2, NM_198995.2 [Q5BJE1-2]
XP_011524250.1, XM_011525948.1 [Q5BJE1-1]
XP_011524253.1, XM_011525951.1 [Q5BJE1-3]

3D structure databases

SMRiQ5BJE1
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ5BJE1, 1 interactor
STRINGi9606.ENSP00000372576

PTM databases

iPTMnetiQ5BJE1
PhosphoSitePlusiQ5BJE1

Polymorphism and mutation databases

BioMutaiCCDC178
DMDMi209572750

Proteomic databases

jPOSTiQ5BJE1
MaxQBiQ5BJE1
PaxDbiQ5BJE1
PeptideAtlasiQ5BJE1
PRIDEiQ5BJE1
ProteomicsDBi62676
62677 [Q5BJE1-2]
62678 [Q5BJE1-3]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
374864
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000300227; ENSP00000300227; ENSG00000166960 [Q5BJE1-2]
ENST00000383096; ENSP00000372576; ENSG00000166960 [Q5BJE1-1]
ENST00000403303; ENSP00000385591; ENSG00000166960 [Q5BJE1-1]
ENST00000579947; ENSP00000462370; ENSG00000166960 [Q5BJE1-4]
GeneIDi374864
KEGGihsa:374864
UCSCiuc002kxn.3 human [Q5BJE1-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
374864
DisGeNETi374864

GeneCards: human genes, protein and diseases

More...
GeneCardsi
CCDC178

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0014389
HGNCiHGNC:29588 CCDC178
neXtProtiNX_Q5BJE1
OpenTargetsiENSG00000166960
PharmGKBiPA134979792

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IIKF Eukaryota
ENOG411202Z LUCA
GeneTreeiENSGT00390000012215
InParanoidiQ5BJE1
OrthoDBi710456at2759
PhylomeDBiQ5BJE1
TreeFamiTF337479

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
CCDC178 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
374864

Protein Ontology

More...
PROi
PR:Q5BJE1

Gene expression databases

BgeeiENSG00000166960 Expressed in 95 organ(s), highest expression level in sperm
ExpressionAtlasiQ5BJE1 baseline and differential
GenevisibleiQ5BJE1 HS

Family and domain databases

InterProiView protein in InterPro
IPR038826 CCDC178
PANTHERiPTHR35088 PTHR35088, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCC178_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5BJE1
Secondary accession number(s): A6NDC6
, J3KS92, Q6ZP67, Q6ZU20
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 21, 2006
Last sequence update: October 14, 2008
Last modified: May 8, 2019
This is version 93 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 18
    Human chromosome 18: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
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