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UniProtKB - Q5BI72 (Q5BI72_DROME)
Protein
Submitted name:
LP18549p
Gene
Dme_CG4562
Organism
Drosophila melanogaster (Fruit fly)
Status
Functioni
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 478 – 485 | ATPPROSITE-ProRule annotation | 8 |
GO - Molecular functioni
- ABC-type transporter activity Source: InterPro
- ATP binding Source: UniProtKB-UniRule
- hydrolase activity Source: UniProtKB-KW
Keywordsi
Molecular function | HydrolaseImported |
Ligand | ATP-bindingPROSITE-ProRule annotationARBA annotation, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Submitted name: LP18549pImportedSubmitted name: Uncharacterized protein, isoform BImported (EC:3.6.1.3Imported)Submitted name: Uncharacterized protein, isoform DImported |
Gene namesi | Name:Dme_CG4562Imported Synonyms:CT14766Imported, Dmel\CG4562Imported ORF Names:CG4562Imported, Dmel_CG4562Imported |
Organismi | Drosophila melanogaster (Fruit fly)Imported |
Taxonomic identifieri | 7227 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora › |
Proteomesi |
|
Organism-specific databases
FlyBasei | FBgn0038740, CG4562 |
VEuPathDBi | VectorBase:FBgn0038740 |
Subcellular locationi
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 81 – 103 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 136 – 159 | HelicalSequence analysisAdd BLAST | 24 | |
Transmembranei | 216 – 232 | HelicalSequence analysisAdd BLAST | 17 | |
Transmembranei | 238 – 256 | HelicalSequence analysisAdd BLAST | 19 | |
Transmembranei | 325 – 347 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 367 – 385 | HelicalSequence analysisAdd BLAST | 19 | |
Transmembranei | 733 – 755 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 799 – 825 | HelicalSequence analysisAdd BLAST | 27 | |
Transmembranei | 869 – 891 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 897 – 916 | HelicalSequence analysisAdd BLAST | 20 |
Keywords - Cellular componenti
MembraneExpressioni
Gene expression databases
Bgeei | FBgn0038740, Expressed in digestive system element and 27 other tissues |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 96 – 368 | ABC transmembrane type-1InterPro annotationAdd BLAST | 273 | |
Domaini | 443 – 666 | ABC transporterInterPro annotationAdd BLAST | 224 | |
Domaini | 742 – 931 | ABC transmembrane type-1InterPro annotationAdd BLAST | 190 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 668 – 697 | DisorderedSequence analysisAdd BLAST | 30 |
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000165791 |
HOGENOMi | CLU_000604_27_14_1 |
Family and domain databases
Gene3Di | 1.20.1560.10, 2 hits 3.40.50.300, 1 hit |
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR011527, ABC1_TM_dom IPR036640, ABC1_TM_sf IPR003439, ABC_transporter-like_ATP-bd IPR017871, ABC_transporter-like_CS IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF00664, ABC_membrane, 2 hits PF00005, ABC_tran, 1 hit |
SMARTi | View protein in SMART SM00382, AAA, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit SSF90123, SSF90123, 2 hits |
PROSITEi | View protein in PROSITE PS50929, ABC_TM1F, 2 hits PS00211, ABC_TRANSPORTER_1, 1 hit PS50893, ABC_TRANSPORTER_2, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
Q5BI72-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MQSMKADELP ENPREKSNIF SSLMFCFAMP TFFKGRKKTL DENDLYRALQ
60 70 80 90 100
EHRSDHLGSK LSAAWEKEVE KKRKKKKTPS LLKASMNVFG WRLAGLGLVL
110 120 130 140 150
FILEIGFRVT QPLFLGGLVA YYADASNQEG DNQTKAYLYA LGVILTSACN
160 170 180 190 200
VLFMHPYMLG MFHIGMKARI AMTSMIYRKA LRLSRTALGD TTIGQVVNLI
210 220 230 240 250
SNDVGRLDVS VIHMNYLWLG PVEIGIITYL MYREIGISAF FGVAVMLLFI
260 270 280 290 300
PLQAYLGKKT SVLRLKTALR TDERVRMMNE IISGIQVIKM YAWEIPFSKM
310 320 330 340 350
INYVRTKEMN AIRNVNYIRG TLQSFIMFVT RISVFVSLVG FVLLGKLLTA
360 370 380 390 400
EKAFVITAYY NILRNTMTVY FPMGISQFAE LLVSIRRIQT FMLHEETKVR
410 420 430 440 450
DKSEDLDEQK LGKAGLIAEP TVAQTTGVLK PSSRRTSEAE HSIVISKLKA
460 470 480 490 500
KWDQKNTDNT LDNISLKFKP RQLVAVIGPV GSGKSSLIQA VLGELNPDSG
510 520 530 540 550
SVKVNGTLSY ASQEPWLFTG TVRQNILFGL PMDKHRYRTV VKRCALERDF
560 570 580 590 600
ELLPYADKTI VGERGASLSG GQKARISLAR AVYRKADIYL LDDPLSAVDT
610 620 630 640 650
HVGRHLFDQC MRGFLREEIV LLVTHQLQFL EQADVIVIMD KGKISAMGTY
660 670 680 690 700
ESMAKSGLDF AQMLTDPSKK DEGAGDAPDK KSLSRQNSKL RDRHGSISSM
710 720 730 740 750
ESAAESLAAE SPMQTQEGRV EGRIGMKLYK KYFGANGYGL FIVFAFFCIG
760 770 780 790 800
AQVLASGGDI FLSYWVNKNG EAERDTFMAR LRRAFPETRI NADTDPVDIY
810 820 830 840 850
YFTGINVSVI IFSLVRSMLF FYLAMRSSTT LHNTMFQGVT RAAMHFFNTN
860 870 880 890 900
PSGRILNRFS KDLGQVDEIL PSVMMDVMQI FLAIVGIVVV LCIINVWYIL
910 920 930 940
ATVFLVIVFY LLRVFYLSTS RDVKRLEAVS LLNQYILYQQ HAPPFTPT
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A0B4KGI0 | A0A0B4KGI0_DROME | Uncharacterized protein, isoform E | Dmel\CG4562 CT14766, Dme_CG4562, CG4562, Dmel_CG4562 | 1,408 | Annotation score: | ||
Q9VDT3 | Q9VDT3_DROME | Uncharacterized protein, isoform A | Dmel\CG4562 CT14766, Dme_CG4562, CG4562, Dmel_CG4562 | 1,362 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BT021352 mRNA Translation: AAX33500.1 AE014297 Genomic DNA Translation: ABW08706.1 AE014297 Genomic DNA Translation: AGB96126.1 |
RefSeqi | NP_001097841.1, NM_001104371.2 NP_001262746.1, NM_001275817.1 |
Genome annotation databases
EnsemblMetazoai | FBtr0113250; FBpp0112162; FBgn0038740 FBtr0330035; FBpp0303068; FBgn0038740 |
GeneIDi | 42362 |
KEGGi | dme:Dmel_CG4562 |
UCSCi | CG4562-RB, d. melanogaster |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BT021352 mRNA Translation: AAX33500.1 AE014297 Genomic DNA Translation: ABW08706.1 AE014297 Genomic DNA Translation: AGB96126.1 |
RefSeqi | NP_001097841.1, NM_001104371.2 NP_001262746.1, NM_001275817.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protocols and materials databases
DNASUi | 42362 |
Genome annotation databases
EnsemblMetazoai | FBtr0113250; FBpp0112162; FBgn0038740 FBtr0330035; FBpp0303068; FBgn0038740 |
GeneIDi | 42362 |
KEGGi | dme:Dmel_CG4562 |
UCSCi | CG4562-RB, d. melanogaster |
Organism-specific databases
FlyBasei | FBgn0038740, CG4562 |
VEuPathDBi | VectorBase:FBgn0038740 |
Phylogenomic databases
GeneTreei | ENSGT00940000165791 |
HOGENOMi | CLU_000604_27_14_1 |
Miscellaneous databases
BioGRID-ORCSi | 42362, 0 hits in 1 CRISPR screen |
GenomeRNAii | 42362 |
Gene expression databases
Bgeei | FBgn0038740, Expressed in digestive system element and 27 other tissues |
Family and domain databases
Gene3Di | 1.20.1560.10, 2 hits 3.40.50.300, 1 hit |
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR011527, ABC1_TM_dom IPR036640, ABC1_TM_sf IPR003439, ABC_transporter-like_ATP-bd IPR017871, ABC_transporter-like_CS IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF00664, ABC_membrane, 2 hits PF00005, ABC_tran, 1 hit |
SMARTi | View protein in SMART SM00382, AAA, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit SSF90123, SSF90123, 2 hits |
PROSITEi | View protein in PROSITE PS50929, ABC_TM1F, 2 hits PS00211, ABC_TRANSPORTER_1, 1 hit PS50893, ABC_TRANSPORTER_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Q5BI72_DROME | |
Accessioni | Q5BI72Primary (citable) accession number: Q5BI72 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 12, 2005 |
Last sequence update: | April 12, 2005 | |
Last modified: | May 25, 2022 | |
This is version 158 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |