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Entry version 77 (08 May 2019)
Sequence version 1 (26 Apr 2005)
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Protein
Submitted name:

Nuclear pore complex protein An-Nup120 (Eurofung)

Gene

ANIA_01238

Organism
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Nuclear pore complex protein An-Nup120 (Eurofung)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:ANIA_01238Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEmericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri227321 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000560 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome VIII

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
162425.CADANIAP00001385

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

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HOGENOMi
HOG000207840

KEGG Orthology (KO)

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KOi
K14303

Identification of Orthologs from Complete Genome Data

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OMAi
WTLWKNN

Database of Orthologous Groups

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OrthoDBi
284127at2759

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR021717 Nucleoporin_Nup160
IPR011047 Quinoprotein_ADH-like_supfam
IPR019775 WD40_repeat_CS

The PANTHER Classification System

More...
PANTHERi
PTHR21286 PTHR21286, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50998 SSF50998, 1 hit

PROSITE; a protein domain and family database

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PROSITEi
View protein in PROSITE
PS00678 WD_REPEATS_1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q5BDZ2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAKIYKDTQV DLRPYSPSTI VNIPIPTQTG SQNRARFAIS SLTDLAEPIA
60 70 80 90 100
KDEDEFARRY IATQGSVYFR KRNVYPRAFL WRVVNESTVL EIQCVDLTKG
110 120 130 140 150
GIENHEYNIT LRLDFQDKIL PSGVALADLE DHDVLNLFVI TASKELHTLA
160 170 180 190 200
LRPEFFRKPA SIDQNISDWC KSYIPAPLAF SHPHRLHASS PLELFISLDS
210 220 230 240 250
GALLRLTRRA ADDGSNWSPL TLDERTWGSS LRGLVRWNAQ SSIKYGGRTL
260 270 280 290 300
DTNVANAVAT TSDQTYVFAV CLNHTLKIWN LATNKLVATK DLLGREMQQN
310 320 330 340 350
SLTYSLNPAE SSFIRVFNVE RALDGGYRYY AVTYSPFEDG CFKFWAIKGG
360 370 380 390 400
LTTPLEIEDL FPAATLRPLD PDSTGNMFWS IADFQVKPAE EGKRMELWVL
410 420 430 440 450
WRNSGLYQLY TLHFNFESLV SDWANNWTTA ASDTRRQELP PPLPISDVVD
460 470 480 490 500
PTEKWLKFLL QPNRFPTEVL ETSLTIYQEA LKPLSSSSTS KKSTPLVERL
510 520 530 540 550
CSTFAATVSL RKFEDDDMDF SRYRSDTDSK WRQFWQIADD LNKRRFEPLT
560 570 580 590 600
LSYDVYYETP WVLLSDSCAV VRECSSTELL LHNPGPVLQS EGPKIADRWR
610 620 630 640 650
HRNLESELGD LYEEASHLMT VASNFRKRFS ADLNAACQSA IEAEIFAEPS
660 670 680 690 700
SSVQDRMEVF RDRCDISEQI SNQIYNDLIS EMNEKLNIYM LSSDIFFKIL
710 720 730 740 750
GTIPLGFPGK DSDLLPTHFG VKVTVNGVQE TIQFTRQILI DLLVLVVFID
760 770 780 790 800
AEVEQDKGST FDAVELFVEL VTLLREYEMM LWLSSNMRKE TDKFSKAAED
810 820 830 840 850
FPNPSFSLKQ LPSSDKSARI TTILEDLFAT DIKPRQAIGL PQSYILTLGI
860 870 880 890 900
QDVLSWCDLI AKGNIDLAWD FLRFQPSTSW STYVKGRLYV AMSELDTAAL
910 920 930 940 950
YFRKAAYLLS CGKPLGNLHE MSSTLLDIVS VDCFHNGLPK YFQHVLSIFE
960 970 980 990 1000
QVRAFSHVSE FASLALQALA SEHGSEQDVE VARLKNDLLS RLFYASLQTC
1010 1020 1030 1040 1050
QFDQAYSALS RYKDSALQKS ALNSLITSIL AASGSGSAGL EQILAFPTTL
1060 1070 1080 1090 1100
IPNLASHVDE ILVSLAQKQP STSPFDTKSR WTEGTVDYQR ILQAYRIKRG
1110 1120 1130 1140 1150
DYRGAAEVAY HNVERLRQAR DTSTHHLLSK AKAGDPLHHI LEEDDPESNE
1160 1170 1180 1190 1200
IRHELLSLIN LLACVDKSEA YILVDKKEAR SLTAHSNASL VAAAGPENDD
1210 1220 1230 1240 1250
ENVFMDDADV PTARHGSISN LRFLSNKPSV SLPPPTSPAQ GPRRRVIVTL
1260 1270 1280 1290
DHLRREYQLE LDRVNRIERG DWEFGLDDGV GFDLERNVAD NVDTMPLA
Length:1,298
Mass (Da):146,572
Last modified:April 26, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i446597C7871DE00A
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BN001308 Genomic DNA Translation: CBF87876.1

NCBI Reference Sequences

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RefSeqi
XP_658842.1, XM_653750.1

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
CBF87876; CBF87876; ANIA_01238
EAA65831; EAA65831; AN1238.2

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
2877016

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ani:AN1238.2

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BN001308 Genomic DNA Translation: CBF87876.1
RefSeqiXP_658842.1, XM_653750.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi162425.CADANIAP00001385

Genome annotation databases

EnsemblFungiiCBF87876; CBF87876; ANIA_01238
EAA65831; EAA65831; AN1238.2
GeneIDi2877016
KEGGiani:AN1238.2

Phylogenomic databases

HOGENOMiHOG000207840
KOiK14303
OMAiWTLWKNN
OrthoDBi284127at2759

Family and domain databases

InterProiView protein in InterPro
IPR021717 Nucleoporin_Nup160
IPR011047 Quinoprotein_ADH-like_supfam
IPR019775 WD40_repeat_CS
PANTHERiPTHR21286 PTHR21286, 1 hit
SUPFAMiSSF50998 SSF50998, 1 hit
PROSITEiView protein in PROSITE
PS00678 WD_REPEATS_1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ5BDZ2_EMENI
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5BDZ2
Secondary accession number(s): C8VSQ2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 26, 2005
Last sequence update: April 26, 2005
Last modified: May 8, 2019
This is version 77 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
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