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Protein

Mitochondrial import inner membrane translocase subunit TIM44

Gene

AN1281.2

Organism
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.UniRule annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processProtein transport, TranslocationUniRule annotation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Mitochondrial import inner membrane translocase subunit TIM44UniRule annotation
Gene namesi
ORF Names:AN1281.2Imported
OrganismiEmericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)Imported
Taxonomic identifieri227321 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000005890 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membraneUniRule annotation

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliQ5BDU9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini359 – 513Tim44InterPro annotationAdd BLAST155

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili79 – 110Sequence analysisAdd BLAST32

Sequence similaritiesi

Belongs to the Tim44 family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

HOGENOMiHOG000208172
KOiK17804

Family and domain databases

InterProiView protein in InterPro
IPR032710 NTF2-like_dom_sf
IPR017303 Tim44
IPR039544 Tim44-like
IPR007379 Tim44-like_dom
PANTHERiPTHR10721 PTHR10721, 1 hit
PfamiView protein in Pfam
PF04280 Tim44, 1 hit
PIRSFiPIRSF037871 TIM44, 1 hit
SMARTiView protein in SMART
SM00978 Tim44, 1 hit
SUPFAMiSSF54427 SSF54427, 1 hit

Sequencei

Sequence statusi: Complete.

Q5BDU9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MIAATRLPAT ARVAALRSQV LALRATGGNS AALQRSLIQS PLYATSRSID
60 70 80 90 100
CAKSPVSRLL SPYASLHLTR SFHVGTPRLQ QKQEQTEKKS EETKQEKNEE
110 120 130 140 150
SKDEDKSEQK KEDKEDAPPP PPHGDKSPWQ VFRDTLQQEF KASKEWNEST
160 170 180 190 200
KALASSAHQF AENENVKRAR AAYEAAQGAA SSRTASALKG TGRVIGKSAS
210 220 230 240 250
WTWNTPVVKG LRKGVNATTS GIEKATRPVR ETEVYKTAVG GVKQAIDDGS
260 270 280 290 300
SSRYGGWTEK EERRRMRQLR EQEELKSGRR KAEPMVEDPN NYVISAGTNI
310 320 330 340 350
TLHKDSAWKE SWREFKDSNP MMQKLFSLKE TYNESENPLI STARSISDRI
360 370 380 390 400
AGFFAENETA QVVKKFREMD PNFQMEAFLR EMREYILPEV LDAYVKGDIE
410 420 430 440 450
TLKLWLSDAQ FHVYEALTKQ ITTAGLKSDG RILDIRGVDV MSARMLDPGD
460 470 480 490 500
IPVFVVMCRT QEVHVYRNVK TNELAAGMED KVQLVNYVMG LTRIPEDVNN
510
PETKGWRLIE LQKAARDYI
Length:519
Mass (Da):58,463
Last modified:April 26, 2005 - v1
Checksum:i9EF78794AF5BFD7D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACD01000017 Genomic DNA Translation: EAA65874.1
RefSeqiXP_658885.1, XM_653793.1

Genome annotation databases

EnsemblFungiiEAA65874; EAA65874; AN1281.2
GeneIDi2877060
KEGGiani:AN1281.2

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACD01000017 Genomic DNA Translation: EAA65874.1
RefSeqiXP_658885.1, XM_653793.1

3D structure databases

ProteinModelPortaliQ5BDU9
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiEAA65874; EAA65874; AN1281.2
GeneIDi2877060
KEGGiani:AN1281.2

Phylogenomic databases

HOGENOMiHOG000208172
KOiK17804

Family and domain databases

InterProiView protein in InterPro
IPR032710 NTF2-like_dom_sf
IPR017303 Tim44
IPR039544 Tim44-like
IPR007379 Tim44-like_dom
PANTHERiPTHR10721 PTHR10721, 1 hit
PfamiView protein in Pfam
PF04280 Tim44, 1 hit
PIRSFiPIRSF037871 TIM44, 1 hit
SMARTiView protein in SMART
SM00978 Tim44, 1 hit
SUPFAMiSSF54427 SSF54427, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ5BDU9_EMENI
AccessioniPrimary (citable) accession number: Q5BDU9
Entry historyiIntegrated into UniProtKB/TrEMBL: April 26, 2005
Last sequence update: April 26, 2005
Last modified: November 7, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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