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Entry version 95 (07 Oct 2020)
Sequence version 2 (15 Mar 2017)
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Protein

Sterol 3-beta-glucosyltransferase

Gene

ATG26

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Probable sterol 3-beta-glucosyltransferase that is not involved in cytoplasm to vacuole transport (Cvt), pexophagy or nonselective autophagy (By similarity).By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGlycosyltransferase, Transferase
Biological processLipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism

Enzyme and pathway databases

BRENDA Comprehensive Enzyme Information System

More...
BRENDAi
2.4.1.173, 1096

Protein family/group databases

Carbohydrate-Active enZymes

More...
CAZyi
GT1, Glycosyltransferase Family 1

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Sterol 3-beta-glucosyltransferaseCurated (EC:2.4.1.173Curated)
Alternative name(s):
Autophagy-related protein 26By similarity
UDP-glycosyltransferase 51
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ATG26By similarity
Synonyms:UGT51, UGT51C, UGT51C1
Ordered Locus Names:CAALFM_CR02160WA
ORF Names:CaO19.10147, CaO19.2616
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri237561 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000559 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome R

Organism-specific databases

Candida Genome Database

More...
CGDi
CAL0000189652, UGT51C1

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
FungiDB:CR_02160W_A

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002156071 – 1512Sterol 3-beta-glucosyltransferaseAdd BLAST1512

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
5476.C4YL47

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q5A950

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini296 – 331GRAM 1Sequence analysisAdd BLAST36
Domaini359 – 520PHPROSITE-ProRule annotationAdd BLAST162
Domaini816 – 880GRAM 2Sequence analysisAdd BLAST65

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi57 – 62Poly-Asp6
Compositional biasi190 – 234Thr-richAdd BLAST45
Compositional biasi1466 – 1485Asp-richAdd BLAST20
Compositional biasi1486 – 1491Poly-Glu6

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the glycosyltransferase 28 family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1192, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000537_6_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q5A950

KEGG Orthology (KO)

More...
KOi
K05841

Database of Orthologous Groups

More...
OrthoDBi
1024049at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.30.29.30, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR004276, GlycoTrans_28_N
IPR004182, GRAM
IPR011993, PH-like_dom_sf
IPR001849, PH_domain
IPR002213, UDP_glucos_trans

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03033, Glyco_transf_28, 1 hit
PF02893, GRAM, 1 hit
PF00201, UDPGT, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00568, GRAM, 2 hits
SM00233, PH, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50003, PH_DOMAIN, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q5A950-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSFYKKVTRG LATPLQGSIN LFSGSPNVSG DEGTDADNEN PEHRTTYHSL
60 70 80 90 100
SGRVNHDDDD EDVAKLEDIV GFFTGLLNTT TVCAGLGSLN NLKKHYLDEF
110 120 130 140 150
IKKSALNPLR PQNYGPETSS KLNNNSIEEL LNNGDTSLEK VRKMSLYDFD
160 170 180 190 200
EHTSDSEEED SADKEEESIA ENLKPGKSGK ARNHPRDSRT TATLITTQIT
210 220 230 240 250
RTKTATTATP TPTPTSSVDT DVTDVTEPIG KVTTKIPEEQ LQGLNPLQKS
260 270 280 290 300
VVKNLDPHHV REGVLIKVKN SETPLKNDRQ ELLEKIQLRL KIADKLQRVF
310 320 330 340 350
DLSDEDTFCG NYSAWLIKDV LLQGHVYLTK DALLYFAFLP KRFSLENSSE
360 370 380 390 400
VLDEDNSSSI VYSGNLGLKS AKYGEVVLNT VLQHRYWAVL RAETLSIYSS
410 420 430 440 450
STNLYFPVLV IDIKKCLYTE IIDKEKLNRE AISPVNRGTY SPNGGLSGTA
460 470 480 490 500
TPRASTLENT ASELNSMLSG DSYSPTEDNV ETTASTVWFK LVTKKKTYKF
510 520 530 540 550
SCDSSFSARQ WCNNITKLIF QHNNANSNGE VLIKIPISKI AEYNKRALFS
560 570 580 590 600
EEEEEDRTLD VTMNDIPLNV TIKYLGDNDN ERKRDKLKRK YKGEEPTIEE
610 620 630 640 650
VHFLFPKSGV EFFETFDKLV NPVVSDNDNQ SSKSSITSTN FSEKAISTLS
660 670 680 690 700
KSPNHLVQTV LDFNKPVDDD ISAFKKFGTT ITSPTRIFKA TITSPEMTSI
710 720 730 740 750
DETSLRDSFD SDRLHLPRDM SERALKNLEV SFVTSLKKLE DASKRYEKPH
760 770 780 790 800
MEHSQTNLAS ILSDPSEVKK ESKTAISKSI KALYSVGTHW SATPNHYFEL
810 820 830 840 850
GKYYVNKVQD RDSSQRNFQS HFSTNSKLLA SYYGHLLRTV PVYGKIYVSE
860 870 880 890 900
TDVCFRSLLP GVSTKMVLPM TDIEEVRASR GSRLTYHGLR LIVRGSEELD
910 920 930 940 950
LEFGSSKSRD DFQKVVLSVL ERLHSKEGFR PEPYQWGSNF EVELYKTRME
960 970 980 990 1000
YSDSENREIQ QYDNSIDIKF AEKKIEMARV RMFEDRLMAA SGLDVPIILE
1010 1020 1030 1040 1050
DSPFFKTELR PSTSYNITLL TIGSRGDVQP YIALGKGLVK EGHNVTIATH
1060 1070 1080 1090 1100
AEFGDWIKTF GLGFKEIAGD PAELMSFMVT HNSMSVGFLK NAQQKFRSWI
1110 1120 1130 1140 1150
SKLLTTSWEA CQGSDILIES PSAMSGIHIA EALGIPYFRA FTMPWTRTRA
1160 1170 1180 1190 1200
YPHAFFVPEQ KKGGSYNYLT HVLFENIFWK GISGQVNKWR VEELDLPKTN
1210 1220 1230 1240 1250
LYRLQQTRVP FLYNVSPAIL PPSVDFPDWI KVTGYWFLDE GSGDYKPPEE
1260 1270 1280 1290 1300
LVQFMKKASR DKKKIVYIGF GSIVVKDAKS LTKAVVSAVR RADVRCILNK
1310 1320 1330 1340 1350
GWSDRLDNKD KNEIEIELPP EIYNSGTIPH DWLFPRIDAA VHHGGSGTTG
1360 1370 1380 1390 1400
ATMRAGIPTI IKPFFGDQFF YATRIEDLGA GIALKKLTAK TLGDALVKAT
1410 1420 1430 1440 1450
HDLKIIDKAK RVSQQIKHEH GVLSAIESIY SELEYSRNLI LIKDIHNQNY
1460 1470 1480 1490 1500
KRHHPVPSGV QTPAYDTDSD DYDDDEDDDE SDKDDEEEEE ENSYDGYDGN
1510
GVNNSPSQNS SN
Length:1,512
Mass (Da):170,442
Last modified:March 15, 2017 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0648684CBDF93866
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti164K → E in AAD29571 (PubMed:10224056).Curated1
Sequence conflicti203K → RTA in AAD29571 (PubMed:10224056).Curated1
Sequence conflicti235K → E in AAD29571 (PubMed:10224056).Curated1
Sequence conflicti561V → A in AAD29571 (PubMed:10224056).Curated1
Sequence conflicti625S → L in AAD29571 (PubMed:10224056).Curated1
Sequence conflicti810D → E in AAD29571 (PubMed:10224056).Curated1
Sequence conflicti1130A → G in AAD29571 (PubMed:10224056).Curated1
Sequence conflicti1491E → EEE in AAD29571 (PubMed:10224056).Curated1
Sequence conflicti1506P → R in AAD29571 (PubMed:10224056).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF091398 Genomic DNA Translation: AAD29571.1
CP017630 Genomic DNA Translation: AOW30966.1

NCBI Reference Sequences

More...
RefSeqi
XP_718281.2, XM_713188.2

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
3640147

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cal:CAALFM_CR02160WA

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF091398 Genomic DNA Translation: AAD29571.1
CP017630 Genomic DNA Translation: AOW30966.1
RefSeqiXP_718281.2, XM_713188.2

3D structure databases

SMRiQ5A950
ModBaseiSearch...

Protein-protein interaction databases

STRINGi5476.C4YL47

Protein family/group databases

CAZyiGT1, Glycosyltransferase Family 1

Genome annotation databases

GeneIDi3640147
KEGGical:CAALFM_CR02160WA

Organism-specific databases

CGDiCAL0000189652, UGT51C1
EuPathDBiFungiDB:CR_02160W_A

Phylogenomic databases

eggNOGiKOG1192, Eukaryota
HOGENOMiCLU_000537_6_0_1
InParanoidiQ5A950
KOiK05841
OrthoDBi1024049at2759

Enzyme and pathway databases

BRENDAi2.4.1.173, 1096

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q5A950

Family and domain databases

Gene3Di2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR004276, GlycoTrans_28_N
IPR004182, GRAM
IPR011993, PH-like_dom_sf
IPR001849, PH_domain
IPR002213, UDP_glucos_trans
PfamiView protein in Pfam
PF03033, Glyco_transf_28, 1 hit
PF02893, GRAM, 1 hit
PF00201, UDPGT, 1 hit
SMARTiView protein in SMART
SM00568, GRAM, 2 hits
SM00233, PH, 1 hit
PROSITEiView protein in PROSITE
PS50003, PH_DOMAIN, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiATG26_CANAL
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5A950
Secondary accession number(s): A0A1D8PS52, Q5A9F2, Q9Y752
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 16, 2005
Last sequence update: March 15, 2017
Last modified: October 7, 2020
This is version 95 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Candida albicans
    Candida albicans: entries and gene names
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