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UniProtKB - Q5A741 (Q5A741_CANAL)

Entry version 75 (07 Oct 2020)
Sequence version 1 (26 Apr 2005)
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Protein
Submitted name:

Opt5p

Gene

OPT5

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processPeptide transportARBA annotation, Protein transport, Transport

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Opt5pImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:OPT5Imported
Ordered Locus Names:orf19.5121Imported
ORF Names:CAALFM_C208360CAImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri237561 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Debaryomycetaceae › Candida/Lodderomyces clade › Candida ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000559 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Candida Genome Database

More...CGDi		CAL0000182685, OPT5

Eukaryotic Pathogen and Host Database Resources

More...EuPathDBi		FungiDB:C2_08360C_A

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei217 – 235HelicalSequence analysisAdd BLAST19
Transmembranei242 – 264HelicalSequence analysisAdd BLAST23
Transmembranei324 – 344HelicalSequence analysisAdd BLAST21
Transmembranei386 – 404HelicalSequence analysisAdd BLAST19
Transmembranei424 – 442HelicalSequence analysisAdd BLAST19
Transmembranei463 – 481HelicalSequence analysisAdd BLAST19
Transmembranei529 – 551HelicalSequence analysisAdd BLAST23
Transmembranei599 – 619HelicalSequence analysisAdd BLAST21
Transmembranei625 – 645HelicalSequence analysisAdd BLAST21
Transmembranei657 – 677HelicalSequence analysisAdd BLAST21
Transmembranei707 – 726HelicalSequence analysisAdd BLAST20
Transmembranei776 – 793HelicalSequence analysisAdd BLAST18
Transmembranei853 – 876HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		5476.C4YKC3

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q5A741

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili88 – 108Sequence analysisAdd BLAST21

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the oligopeptide OPT transporter family.ARBA annotation

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysisARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG2262, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_004965_1_0_1

Identification of Orthologs from Complete Genome Data

More...OMAi		VFINCFI

Database of Orthologous Groups

More...OrthoDBi		246409at2759

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR004648, Oligpept_transpt
IPR004813, OPT

Pfam protein domain database

More...Pfami		View protein in Pfam
PF03169, OPT, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR00727, ISP4_OPT, 1 hit
TIGR00728, OPT_sfam, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q5A741-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSTEKPIPAL PVTSITSHVD VAAHEVNLQA ITSNPLSIGE VGTTLTNGQK 
        60         70         80         90        100
DFILKRLHYD SLVSFDKLPP QATFIFEKIE HISIEEALAI LEKAVVEHEN 
       110        120        130        140        150
DVNILDNDEE LWTKLINYKQ GKIPSDTDFS EKAHPSNFTA KDKLSAFIHE 
       160        170        180        190        200
KRVSEETSSL DNSASENLNE PYYKIVDWEL QVKLEAVLIA YWSPYPQVRG 
       210        220        230        240        250
VTDPYDDPTI PVETVRVYIV AIIWTAIGAV INQFFSERQP SIGLGMSVVQ 
       260        270        280        290        300
VFLYPTGLIC EWILPKWKFK VWKYTIDLNP GPYTFKEQML ATIFCGVSSG 
       310        320        330        340        350
TSYVSSNILM QKSELFYDNK WVDFGYQVLL TLSTNFLGFG LSGIMRQFAV 
       360        370        380        390        400
YPEKAIWPSI LPNVRLNKTL MSPEVKARIN GWSISGYNFF FITAGISFLY 
       410        420        430        440        450
FWIPDYLFQA LSQFNWMTWI KPDNYNLAVV TGSFGGLGLN PIPSFDMNVI 
       460        470        480        490        500
GTGGFIAPFY NTLESYIGMV LALFCILGVF YSNYKWTGFL PINSNRLFTN 
       510        520        530        540        550
EGKPYHVTAV VNSNSLFDEE KYKEVGPPFY SAGNLVLYGA FFAIYPFHFV 
       560        570        580        590        600
YEIAMNYKQM WEALQSLYKG IRNFKRSTYE GFDDPHSVMM RAYPEVPEWA 
       610        620        630        640        650
YLIILVISLV LAILCVKLYP AETPVWGIFF ALAINFVFLI PLTTVQSRTM 
       660        670        680        690        700
FGFGLNVLVE LIVGYAIPGN GLALAFIKAL GYNIDGQAQN FINDLKQGHY 
       710        720        730        740        750
AKLPPRAMYR CQLLSVFITS FIQLGILNYQ ITGIKDYCVP GNKQKFTCPG 
       760        770        780        790        800
TTTFYNASVL WGVIGPKKVF NGLYPILAWC FLIGFLLAFP CIAFKKWAPR 
       810        820        830        840        850
KYSKYFEPSI IIGGFLGYAP YNLSYNTGGL YVGYAFMHYV KRKYEAWWQK 
       860        870        880        890        900
YDYLLATGID AGIAFSSIII FFAVMYHEKD ISWWGNNVPF EGWDASMTNG 
       910        920 
YLNATLQAPD GYFGPRVGHF P
Length:921
Mass (Da):104,433
Last modified:April 26, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i613350B8E501BDFF
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
CP017624 Genomic DNA Translation: AOW27826.1

NCBI Reference Sequences

More...RefSeqi		XP_717657.1, XM_712564.2

Genome annotation databases

Ensembl fungal genome annotation project

More...EnsemblFungii		KHC81858; KHC81858; W5Q_02250
KHC88189; KHC88189; I503_02264

Database of genes from NCBI RefSeq genomes

More...GeneIDi		3640768

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		cal:CAALFM_C208360CA

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP017624 Genomic DNA Translation: AOW27826.1
RefSeqiXP_717657.1, XM_712564.2

3D structure databases

SMRiQ5A741
ModBaseiSearch...

Protein-protein interaction databases

STRINGi5476.C4YKC3

Genome annotation databases

EnsemblFungiiKHC81858; KHC81858; W5Q_02250
KHC88189; KHC88189; I503_02264
GeneIDi3640768
KEGGical:CAALFM_C208360CA

Organism-specific databases

CGDiCAL0000182685, OPT5
EuPathDBiFungiDB:C2_08360C_A

Phylogenomic databases

eggNOGiKOG2262, Eukaryota
HOGENOMiCLU_004965_1_0_1
OMAiVFINCFI
OrthoDBi246409at2759

Family and domain databases

InterProiView protein in InterPro
IPR004648, Oligpept_transpt
IPR004813, OPT
PfamiView protein in Pfam
PF03169, OPT, 1 hit
TIGRFAMsiTIGR00727, ISP4_OPT, 1 hit
TIGR00728, OPT_sfam, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ5A741_CANAL
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5A741
Secondary accession number(s): Q1KY73
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 26, 2005
Last sequence update: April 26, 2005
Last modified: October 7, 2020
This is version 75 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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