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UniProtKB - Q59LX9 (BTN1_CANAL)
Protein
Protein BTN1
Gene
BTN1
Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Functioni
Involved in vacuolar transport and vacuole pH homeostasis. Also required for cytokinesis (By similarity).
By similarityGO - Biological processi
- L-arginine transmembrane transport Source: EnsemblFungi
- lysine transport Source: EnsemblFungi
- regulation of intracellular pH Source: GO_Central
Keywordsi
Biological process | Amino-acid transport, Transport |
Protein family/group databases
TCDBi | 2.A.57.5.3, the equilibrative nucleoside transporter (ent) family |
Names & Taxonomyi
Protein namesi | Recommended name: Protein BTN1 |
Gene namesi | Name:BTN1 Ordered Locus Names:CAALFM_C105120WA ORF Names:CaO19.11541, CaO19.4059 |
Organismi | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) |
Taxonomic identifieri | 237561 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Debaryomycetaceae › Candida/Lodderomyces clade › Candida › |
Proteomesi |
|
Organism-specific databases
CGDi | CAL0000190783, orf19.4059 |
VEuPathDBi | FungiDB:C1_05120W_A |
Subcellular locationi
Vacuole
- Vacuole membrane By similarity; Multi-pass membrane protein By similarity
Vacuole
- fungal-type vacuole Source: EnsemblFungi
- vacuolar membrane Source: UniProtKB-SubCell
- vacuole Source: GO_Central
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 44 – 64 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 67 – 87 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 99 – 119 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 129 – 149 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 154 – 174 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 243 – 263 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 290 – 310 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 318 – 338 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 340 – 360 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 384 – 404 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
Membrane, VacuolePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 32 | Sequence analysisAdd BLAST | 32 | |
ChainiPRO_0000256257 | 33 – 426 | Protein BTN1Add BLAST | 394 |
Family & Domainsi
Sequence similaritiesi
Belongs to the battenin family.Curated
Keywords - Domaini
Signal, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG3880, Eukaryota |
HOGENOMi | CLU_029663_1_2_1 |
InParanoidi | Q59LX9 |
OrthoDBi | 1037817at2759 |
Family and domain databases
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR003492, Battenin_disease_Cln3 IPR018460, Battenin_disease_Cln3_subgr IPR036259, MFS_trans_sf |
PANTHERi | PTHR10981, PTHR10981, 1 hit |
Pfami | View protein in Pfam PF02487, CLN3, 1 hit |
PIRSFi | PIRSF015974, CLN3_BTN1, 1 hit |
PRINTSi | PR01315, BATTENIN |
SUPFAMi | SSF103473, SSF103473, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
Q59LX9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MFIISETQRT FASFFIFGLL NNILYVIILS AAIDLVGPST PKAIVLLADI
60 70 80 90 100
IPSFSFKVAA PFFIHAVPYI IRLWTLVALS ATGMVLISLS PTNVISWKIL
110 120 130 140 150
GITLASLSSG LGEVSFLQLT HYYEENSAIG GFSSGTGGAG LFGSFLFMVL
160 170 180 190 200
TNVMGFPVWV VLLICAVFPS GFIITYFNLL PLPMHEYQVI LQQQQEREEE
210 220 230 240 250
QEEEEYQQQL QDEARSQNIE SIREVKYSVN YISKHVQNTI HKITPLILPY
260 270 280 290 300
MLPLTTVYIS EYVINQGISP TLLFPLKEVP RWLISSYRDI YVVYGFLYQL
310 320 330 340 350
GVFISRSSVT MGIRIKRLYL LSVLQFINVM ITLYQSIYDL PFHSIWWLFL
360 370 380 390 400
LIFYEGLLGG ASYVNTFKSV SEQVSRTKRE FSMGCVSISD SLGIVTAGCI
410 420
NWWLELKLCH LQVARGRDWC LKGGSL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP017623 Genomic DNA Translation: AOW26183.1 |
RefSeqi | XP_710728.2, XM_705636.2 |
Genome annotation databases
GeneIDi | 3647667 |
KEGGi | cal:CAALFM_C105120WA |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP017623 Genomic DNA Translation: AOW26183.1 |
RefSeqi | XP_710728.2, XM_705636.2 |
3D structure databases
AlphaFoldDBi | Q59LX9 |
SMRi | Q59LX9 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 237561.Q59LX9 |
Protein family/group databases
TCDBi | 2.A.57.5.3, the equilibrative nucleoside transporter (ent) family |
Genome annotation databases
GeneIDi | 3647667 |
KEGGi | cal:CAALFM_C105120WA |
Organism-specific databases
CGDi | CAL0000190783, orf19.4059 |
VEuPathDBi | FungiDB:C1_05120W_A |
Phylogenomic databases
eggNOGi | KOG3880, Eukaryota |
HOGENOMi | CLU_029663_1_2_1 |
InParanoidi | Q59LX9 |
OrthoDBi | 1037817at2759 |
Miscellaneous databases
PROi | PR:Q59LX9 |
Family and domain databases
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR003492, Battenin_disease_Cln3 IPR018460, Battenin_disease_Cln3_subgr IPR036259, MFS_trans_sf |
PANTHERi | PTHR10981, PTHR10981, 1 hit |
Pfami | View protein in Pfam PF02487, CLN3, 1 hit |
PIRSFi | PIRSF015974, CLN3_BTN1, 1 hit |
PRINTSi | PR01315, BATTENIN |
SUPFAMi | SSF103473, SSF103473, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | BTN1_CANAL | |
Accessioni | Q59LX9Primary (citable) accession number: Q59LX9 Secondary accession number(s): A0A1D8PDG8, Q59LY9 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 31, 2006 |
Last sequence update: | March 15, 2017 | |
Last modified: | May 25, 2022 | |
This is version 83 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Candida albicans
Candida albicans: entries and gene names - SIMILARITY comments
Index of protein domains and families