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Protein
Submitted name:

X-ray repair cross complementing protein 1 variant

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

SignaLinkiQ59HH7

Names & Taxonomyi

Protein namesi
Submitted name:
X-ray repair cross complementing protein 1 variantImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA369

PTM / Processingi

Proteomic databases

PeptideAtlasiQ59HH7
PRIDEiQ59HH7

Expressioni

Gene expression databases

GenevisibleiQ59HH7 HS

Structurei

3D structure databases

ProteinModelPortaliQ59HH7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini329 – 417BRCTInterPro annotationAdd BLAST89
Domaini552 – 643BRCTInterPro annotationAdd BLAST92

Phylogenomic databases

eggNOGiKOG3226 Eukaryota
ENOG410ZE1H LUCA
HOGENOMiHOG000111006
HOVERGENiHBG052992
KOiK10803

Family and domain databases

CDDicd00027 BRCT, 2 hits
Gene3Di2.60.120.260, 1 hit
3.40.50.10190, 2 hits
InterProiView protein in InterPro
IPR001357 BRCT_dom
IPR036420 BRCT_dom_sf
IPR008979 Galactose-bd-like_sf
IPR002706 Xrcc1_N
PfamiView protein in Pfam
PF00533 BRCT, 1 hit
PF16589 BRCT_2, 1 hit
PF01834 XRCC1_N, 1 hit
SMARTiView protein in SMART
SM00292 BRCT, 2 hits
SUPFAMiSSF49785 SSF49785, 1 hit
SSF52113 SSF52113, 2 hits
PROSITEiView protein in PROSITE
PS50172 BRCT, 2 hits

Sequencei

Sequence statusi: Fragment.

Q59HH7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
STSSFWPGEA HDVDMPEIRL RHVVSCSSQD STHCAENLLK ADTYRKWRAA
60 70 80 90 100
KAGEKTISVV LQLEKEEQIH SVDIGNDGSA FVEVLVGSSA GGAGEQDYEV
110 120 130 140 150
LLVTSSFMSP SESRSGSNPN RVRMFGPDKL VRAAAEKRWD RVKIVCSQPY
160 170 180 190 200
SKDSPFGLSF VRFHSPPDKD EAEAPSQKVT VTKLGQFRVK EEDESANSLR
210 220 230 240 250
PGALFFSRIN KTSPVTASDP AGPSYAAATL QASSAASSAS PVSRAIGSTS
260 270 280 290 300
KPQESPKGKR KLDLNQEEKK TPSKPPAQLS PSVPKRPKLP APTRTPATAP
310 320 330 340 350
VPARAQGAVT GKPRGEGTEP RRPRAGPEEL GKILQGVVVV LSGFQNPFRS
360 370 380 390 400
ELRDKALELG AKYRPDWTRD STHLICAFAN TPKYSQVLGL GGRIVRKEWV
410 420 430 440 450
LDCHRMRRRL PSQRYLMAGP GSSSEEDEAS HSGGSGDEAP KLPQKQPQTK
460 470 480 490 500
TKPTQAAGPS SPQKPPTPEE TKAASPVLQE DIDIEGVQSE GQDNGAEDSG
510 520 530 540 550
DTEDELRRVA EQKEHRLPPG QEENGEDPYA GSTDENTDSE EHQEPPDLPV
560 570 580 590 600
PELPDFFQGK HFFLYGEFPG DERRKLIRYV TAFNGELEDY MSDRVQFVIT
610 620 630 640
AQEWDPSFEE ALMDNPSLAF VRPRWIYSCN EKQKLLPHQL YGVVPQA
Length:647
Mass (Da):71,014
Last modified:April 26, 2005 - v1
Checksum:i881FBDB515E9926E
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB208781 mRNA Translation: BAD92018.1
RefSeqiNP_006288.2, NM_006297.2
UniGeneiHs.98493

Genome annotation databases

GeneIDi7515
KEGGihsa:7515

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB208781 mRNA Translation: BAD92018.1
RefSeqiNP_006288.2, NM_006297.2
UniGeneiHs.98493

3D structure databases

ProteinModelPortaliQ59HH7
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiQ59HH7
PRIDEiQ59HH7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi7515
KEGGihsa:7515

Organism-specific databases

CTDi7515
PharmGKBiPA369

Phylogenomic databases

eggNOGiKOG3226 Eukaryota
ENOG410ZE1H LUCA
HOGENOMiHOG000111006
HOVERGENiHBG052992
KOiK10803

Enzyme and pathway databases

SignaLinkiQ59HH7

Miscellaneous databases

GenomeRNAii7515

Gene expression databases

GenevisibleiQ59HH7 HS

Family and domain databases

CDDicd00027 BRCT, 2 hits
Gene3Di2.60.120.260, 1 hit
3.40.50.10190, 2 hits
InterProiView protein in InterPro
IPR001357 BRCT_dom
IPR036420 BRCT_dom_sf
IPR008979 Galactose-bd-like_sf
IPR002706 Xrcc1_N
PfamiView protein in Pfam
PF00533 BRCT, 1 hit
PF16589 BRCT_2, 1 hit
PF01834 XRCC1_N, 1 hit
SMARTiView protein in SMART
SM00292 BRCT, 2 hits
SUPFAMiSSF49785 SSF49785, 1 hit
SSF52113 SSF52113, 2 hits
PROSITEiView protein in PROSITE
PS50172 BRCT, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiQ59HH7_HUMAN
AccessioniPrimary (citable) accession number: Q59HH7
Entry historyiIntegrated into UniProtKB/TrEMBL: April 26, 2005
Last sequence update: April 26, 2005
Last modified: January 31, 2018
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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