UniProtKB - Q59HD3 (Q59HD3_HUMAN)
Protein
Submitted name:
Ataxin 2-binding protein 1 isoform 4 variant
Gene
N/A
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- RNA binding Source: UniProtKB-UniRule
GO - Biological processi
- mRNA processing Source: UniProtKB-KW
- regulation of RNA splicing Source: InterPro
Keywordsi
Molecular function | RNA-bindingUniRule annotationARBA annotation |
Biological process | mRNA processingARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Ataxin 2-binding protein 1 isoform 4 variantImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Subcellular locationi
Nucleus
- Nucleus ARBA annotation
Nucleus
- nucleus Source: UniProtKB-SubCell
Keywords - Cellular componenti
NucleusARBA annotationInteractioni
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sitei | 159 | Interaction with RNAUniRule annotation | 1 | |
Sitei | 167 | Interaction with RNAUniRule annotation | 1 | |
Sitei | 168 | Interaction with RNAUniRule annotation | 1 | |
Sitei | 192 | Interaction with RNAUniRule annotation | 1 | |
Sitei | 197 | Interaction with RNAUniRule annotation | 1 | |
Sitei | 201 | Interaction with RNAUniRule annotation | 1 | |
Sitei | 225 | Interaction with RNAUniRule annotation | 1 | |
Sitei | 235 | Interaction with RNAUniRule annotation | 1 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 158 – 234 | RRMInterPro annotationAdd BLAST | 77 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 71 – 165 | DisorderedSequence analysisAdd BLAST | 95 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 97 – 160 | PolarSequence analysisAdd BLAST | 64 |
Phylogenomic databases
OrthoDBi | 871288at2759 |
Family and domain databases
CDDi | cd12407, RRM_FOX1_like, 1 hit |
Gene3Di | 3.30.70.330, 1 hit |
InterProi | View protein in InterPro IPR034237, FOX1_RRM IPR012677, Nucleotide-bd_a/b_plait_sf IPR035979, RBD_domain_sf IPR017325, RNA-bd_Fox-1 IPR000504, RRM_dom |
Pfami | View protein in Pfam PF00076, RRM_1, 1 hit |
PIRSFi | PIRSF037932, Ataxin_2_bd_A2BP, 1 hit |
SMARTi | View protein in SMART SM00360, RRM, 1 hit |
SUPFAMi | SSF54928, SSF54928, 1 hit |
PROSITEi | View protein in PROSITE PS50102, RRM, 1 hit |
i Sequence
Sequence statusi: Fragment.
Q59HD3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
ETGQRTHASG TYSFLDRTQH SDIKADCNTC VEIEDRKVSR QQMNCEREQL
60 70 80 90 100
RGNQEAAAAP DTMAQPYASA QFAPPQNGIP AEYTAPHPHP APEYTGQTTV
110 120 130 140 150
PEHTLNLYPP AQTHSEQSPA DTSAQTVSGT ATTDDAAPTD GQPQTQPSEN
160 170 180 190 200
TENKSQPKRL HVSNIPFRFR DPDLRQMFGQ FGKILDVEII FNERGSKGFG
210 220 230 240 250
FVTFENSADA DRAREKLHGT VVEGRKIEVN NATARVMTNK KTVNPYTNGW
260 270 280 290 300
KLNPVVGAVY SPEFYAGTVL LCQANQEGSS MYSAPSSLVY TSAMPGFPYP
AAT
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 | |
Non-terminal residuei | 303 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB208826 mRNA Translation: BAD92063.1 |
RefSeqi | NP_001135805.1, NM_001142333.1 NP_061193.2, NM_018723.3 |
Genome annotation databases
GeneIDi | 54715 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB208826 mRNA Translation: BAD92063.1 |
RefSeqi | NP_001135805.1, NM_001142333.1 NP_061193.2, NM_018723.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | Q59HD3 |
Protocols and materials databases
DNASUi | 54715 |
Genome annotation databases
GeneIDi | 54715 |
Organism-specific databases
CTDi | 54715 |
Phylogenomic databases
OrthoDBi | 871288at2759 |
Miscellaneous databases
BioGRID-ORCSi | 54715, 5 hits in 986 CRISPR screens |
GenomeRNAii | 54715 |
Gene expression databases
Genevisiblei | Q59HD3, HS |
Family and domain databases
CDDi | cd12407, RRM_FOX1_like, 1 hit |
Gene3Di | 3.30.70.330, 1 hit |
InterProi | View protein in InterPro IPR034237, FOX1_RRM IPR012677, Nucleotide-bd_a/b_plait_sf IPR035979, RBD_domain_sf IPR017325, RNA-bd_Fox-1 IPR000504, RRM_dom |
Pfami | View protein in Pfam PF00076, RRM_1, 1 hit |
PIRSFi | PIRSF037932, Ataxin_2_bd_A2BP, 1 hit |
SMARTi | View protein in SMART SM00360, RRM, 1 hit |
SUPFAMi | SSF54928, SSF54928, 1 hit |
PROSITEi | View protein in PROSITE PS50102, RRM, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q59HD3_HUMAN | |
Accessioni | Q59HD3Primary (citable) accession number: Q59HD3 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 26, 2005 |
Last sequence update: | April 26, 2005 | |
Last modified: | April 7, 2021 | |
This is version 74 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |