UniProtKB - Q59H94 (Q59H94_HUMAN)
Protein
Submitted name:
Gamma filamin variant
Gene
N/A
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Gamma filamin variantImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 1 – 54 | FilaminPROSITE-ProRule annotationAdd BLAST | 54 | |
Repeati | 55 – 150 | FilaminPROSITE-ProRule annotationAdd BLAST | 96 | |
Repeati | 151 – 247 | FilaminPROSITE-ProRule annotationAdd BLAST | 97 | |
Repeati | 260 – 351 | FilaminPROSITE-ProRule annotationAdd BLAST | 92 | |
Repeati | 402 – 471 | FilaminPROSITE-ProRule annotationAdd BLAST | 70 | |
Repeati | 471 – 563 | FilaminPROSITE-ProRule annotationAdd BLAST | 93 | |
Repeati | 561 – 650 | FilaminPROSITE-ProRule annotationAdd BLAST | 90 | |
Repeati | 653 – 745 | FilaminPROSITE-ProRule annotationAdd BLAST | 93 | |
Repeati | 838 – 923 | FilaminPROSITE-ProRule annotationAdd BLAST | 86 | |
Repeati | 926 – 1018 | FilaminPROSITE-ProRule annotationAdd BLAST | 93 | |
Repeati | 1020 – 1113 | FilaminPROSITE-ProRule annotationAdd BLAST | 94 | |
Repeati | 1117 – 1209 | FilaminPROSITE-ProRule annotationAdd BLAST | 93 | |
Repeati | 1247 – 1341 | FilaminPROSITE-ProRule annotationAdd BLAST | 95 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 357 – 382 | DisorderedSequence analysisAdd BLAST | 26 | |
Regioni | 857 – 877 | DisorderedSequence analysisAdd BLAST | 21 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 857 – 875 | PolarSequence analysisAdd BLAST | 19 |
Phylogenomic databases
OrthoDBi | 35998at2759 |
Family and domain databases
Gene3Di | 2.60.40.10, 13 hits |
InterProi | View protein in InterPro IPR017868, Filamin/ABP280_repeat-like IPR001298, Filamin/ABP280_rpt IPR013783, Ig-like_fold IPR014756, Ig_E-set |
Pfami | View protein in Pfam PF00630, Filamin, 12 hits |
SMARTi | View protein in SMART SM00557, IG_FLMN, 13 hits |
SUPFAMi | SSF81296, SSF81296, 13 hits |
PROSITEi | View protein in PROSITE PS50194, FILAMIN_REPEAT, 13 hits |
i Sequence
Sequence statusi: Fragment.
Q59H94-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
GLAIEGPSEA KMSCKDNKDG SCTVEYIPFT PGDYDVNITF GGRPIPGSPF
60 70 80 90 100
RVPVKDVVDP GKVKCSGPGL GAGVRARVPQ TFTVDCSQAG RAPLQVAVLG
110 120 130 140 150
PTGVAEPVEV RDNGDGTHTV HYTPATDGPY TVAVKYADQE VPRSPFKIKV
160 170 180 190 200
LPAHDASKVR ASGPGLNASG IPASLPVEFT IDARDAGEGL LTVQILDPEG
210 220 230 240 250
KPKKANIRDN GDGTYTVSYL PDMSGRYTIT IKYGGDEIPY SPFRIHALPT
260 270 280 290 300
GDASKCLVTV SIGGHGLGAC LGPRIQIGQE TVITVDAKAA GEGKVTCTVS
310 320 330 340 350
TPDGAELDVD VVENHDGTFD IYYTAPEPGK YVITIRFGGE HIPNSPFHVL
360 370 380 390 400
ACDPLPHEEE PSEVPQLRQP YAPPRPGARP THWATEEPVV PVEPMESMLR
410 420 430 440 450
PFNLVIPFAV QKGELTGEVR MPSGKTARPN ITDNKDGTIT VRYAPTEKGL
460 470 480 490 500
HQMGIKYDGN HIPGSPLQFY VDAINSRHVS AYGPGLSHGM VNKPATFTIV
510 520 530 540 550
TKDAGEGGLS LAVEGPSKAE ITCKDNKDGT CTVSYLPTAP GDYSIIVRFD
560 570 580 590 600
DKHIPGSPFT AKITGDDSMR TSQLNVGTST DVSLKITESD LSQLTASIRA
610 620 630 640 650
PSGNEEPCLL KRLPNRHIGI SFTPKEVGEH VVSVRKSGKH VTNSPFKILV
660 670 680 690 700
GPSEIGDASK VRVWGKGLSE GHTFQVAEFI VDTRNAGYGG LGLSIEGPSK
710 720 730 740 750
VDINCEDMED GTCKVTYCPT EPGTYIINIK FADKHVPGSP FTVKVTGEGR
760 770 780 790 800
MKESITRRRQ APSIATIGST CDLNLKIPGN WFQMVSAQER LTRTFTRSSH
810 820 830 840 850
TYTRTERTEI SKTRGGETKR EVRVEESTQV GGDPFPAVFG DFLGRERLGS
860 870 880 890 900
FGSITRQQEG EASSQDMTAQ VTSPSGKVEA AEIVEGEDSA YSVRFVPQEM
910 920 930 940 950
GPHTVAVKYR GQHVPGSPFQ FTVGPLGEGG AHKVRAGGTG LERGVAGVPA
960 970 980 990 1000
EFSIWTREAG AGGLSIAVEG PSKAEIAFED RKDGSCGVSY VVQEPGDYEV
1010 1020 1030 1040 1050
SIKFNDEHIP DSPFVVPVAS LSDDARRLTV TSLQETGLKV NQPASFAVQL
1060 1070 1080 1090 1100
NGARGVIDAR VHTPSGAVEE CYVSELDSDK HTIRFIPHEN GVHSIDVKFN
1110 1120 1130 1140 1150
GAHIPGSPFK IRVGEQSQAG DPGLVSAYGP GLEGGTTGVS SEFIVNTLNA
1160 1170 1180 1190 1200
GSGALSVTID GPSKVQLDCR ECPEGHVVTY TPMAPGNYLI AIKYGGPQHI
1210 1220 1230 1240 1250
VGSPFKAKVT GPRLSGGHSL HETSTVLVET VTKSSSSRGS SYSSIPKFSS
1260 1270 1280 1290 1300
DASKVVTRGP GLSQAFVGQK NSFTVDCSKA GTNMMMVGVH GPKTPCEEVY
1310 1320 1330 1340
VKHMGNRVYN VTYTVKEKGD YILIVKWGDE SVPGSPFKVK VP
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB208865 mRNA Translation: BAD92102.1 |
RefSeqi | NP_001120959.1, NM_001127487.1 NP_001449.3, NM_001458.4 |
Genome annotation databases
GeneIDi | 2318 |
KEGGi | hsa:2318 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB208865 mRNA Translation: BAD92102.1 |
RefSeqi | NP_001120959.1, NM_001127487.1 NP_001449.3, NM_001458.4 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | Q59H94 |
PRIDEi | Q59H94 |
Genome annotation databases
GeneIDi | 2318 |
KEGGi | hsa:2318 |
Organism-specific databases
CTDi | 2318 |
PharmGKBi | PA28174 |
Phylogenomic databases
OrthoDBi | 35998at2759 |
Miscellaneous databases
BioGRID-ORCSi | 2318, 7 hits in 844 CRISPR screens |
EvolutionaryTracei | Q59H94 |
GenomeRNAii | 2318 |
Gene expression databases
Genevisiblei | Q59H94, HS |
Family and domain databases
Gene3Di | 2.60.40.10, 13 hits |
InterProi | View protein in InterPro IPR017868, Filamin/ABP280_repeat-like IPR001298, Filamin/ABP280_rpt IPR013783, Ig-like_fold IPR014756, Ig_E-set |
Pfami | View protein in Pfam PF00630, Filamin, 12 hits |
SMARTi | View protein in SMART SM00557, IG_FLMN, 13 hits |
SUPFAMi | SSF81296, SSF81296, 13 hits |
PROSITEi | View protein in PROSITE PS50194, FILAMIN_REPEAT, 13 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q59H94_HUMAN | |
Accessioni | Q59H94Primary (citable) accession number: Q59H94 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 26, 2005 |
Last sequence update: | April 26, 2005 | |
Last modified: | December 2, 2020 | |
This is version 79 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |